GeneTex

  • Country / Location Selection

United States (US)

Mouse FKBP12 protein, His tag

Mouse FKBP12 protein, His tag. GTX68263-pro

Cat. No. GTX68263-pro

Species

 Mouse
Package
100 μg ($289)
See all FKBP12 protein products

APPLICATION

Observed MW

12 kDa.

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol, 1mM DTT

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MGSHMGVQVE TISPGDGRTF PKRGQTCVVH YTGMLEDGKK FDSSRDRNKP FKFTLGKQEV IRGWEEGVAQ MSVGQRAKLI ISSDYAYGAT GHPGIIPPHA TLVFDVELLK LE

Expression System

E. coli

Purity

> 95% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

FK506 binding protein 1a , FKBP12 , Fkbp , Fkbp1

Cellular Localization

Cytoplasm, cytosol

Background

This gene is a member of the immunophilin family. The encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, and is associated with immunoregulation, protein folding, receptor signaling, protein trafficking and T-cell activation. It may modulate the calcium release activity of the ryanodine receptor Ryr1. It also interacts with the type I TGF-beta receptor. Disruption of this gene in mouse causes severe ventricular defects. Pseudogenes of this gene have been defined on chromosomes 4, 10, 14, and 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Mouse FKBP12 protein, His tag. GTX68263-pro

GTX68263-pro Image

3μg Mouse FKBP12 protein (GTX68263-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

There are currently no references for Mouse FKBP12 protein, His tag (GTX68263-pro). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Mouse FKBP12 protein, His tag (GTX68263-pro). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 289