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United States (US)

CYP17A1 blocking peptide

Cat. No. GTX89365-PEP

Species

Human
Package
100 μg ($239)

APPLICATION

Product Note

The peptide was used in the production of GTX89365.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

C-LFKDGDQKLEK

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Cytochrome P450 Family 17 Subfamily A Member 1 , Cpt7 , Cyp17 , P450C17 , S17Ah , Cyp17A1

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]

Research Area

REFERENCE

There are currently no references for CYP17A1 blocking peptide (GTX89365-PEP). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CYP17A1 blocking peptide (GTX89365-PEP). Be the first to share your experience with this product.
Package List Price ($)
$ 239