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DNase II antibody

Anti-DNase II antibody used in Western Blot (WB). GTX28119
Anti-DNase II antibody used in IHC (Paraffin sections) (IHC-P). GTX28119
Anti-DNase II antibody used in IHC (Paraffin sections) (IHC-P). GTX28119
Anti-DNase II antibody used in IHC (Paraffin sections) (IHC-P). GTX28119

Cat. No. GTX28119

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($479)
See all DNASE2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1μg/ml
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide corresponding to aa 347- 360 of human DNase II precursor (accession no. AF047016).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DNASE2 , DNASE2A , DNL , DNL2 , deoxyribonuclease 2, lysosomal , DNase II

Cellular Localization

Lysosome

Background

This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DNase II antibody used in Western Blot (WB). GTX28119

GTX28119 WB Image

Western blot analysis of DNase II in human spleen tissue lysate in the absence (lane 1) or presence (lane 2) of blocking peptide with DNase II antibody (GTX28119) at 1μg/ml.

Anti-DNase II antibody used in IHC (Paraffin sections) (IHC-P). GTX28119

GTX28119 IHC-P Image

IHC-P analysis of human spleen tissue using GTX28119 DNase II antibody.
Dilution : 5 μg/ml

Anti-DNase II antibody used in IHC (Paraffin sections) (IHC-P). GTX28119

GTX28119 IHC-P Image

Immunohistochemical staining ofDNaseII in human spleen with DNase II antibody (GTX28119) at 5μg/ml.

Anti-DNase II antibody used in IHC (Paraffin sections) (IHC-P). GTX28119

GTX28119 IHC-P Image

IHC-P analysis of human spleen tissue using GTX28119 DNase II antibody.
Green : Primary antibody
Red : Actin
Blue : DAPI
Dilution : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 479