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SCP3 antibody

Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092
Anti-SCP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX15092
Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092
Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092
Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092

Cat. No. GTX15092

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, IHC

Reactivity

 Human, Mouse
Package
100 μl ($419)
See all SCP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF 1:100 - 1:750
IHC-P 1:750
IHC-Fr Assay dependent
IHC 1:750
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A synthetic peptide made to the C-terminal region of the mouse SCP3 protein. [UniProt# P70281]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_369763

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

synaptonemal complex protein 3 , Cor1 , Scp3

Cellular Localization

Nucleus

Background

Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for axial elements (AE) in meiotic cells and for assembly of the synaptonemal complex. May be important for testis development and male fertility.

Database

Research Area

DATA IMAGES

Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092

GTX15092 ICC/IF Image

ICC/IF analysis of mouse pachytene preparation using GTX15092 SCP3 antibody.
Red : primary antibody
Green : CDK2

Anti-SCP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX15092

GTX15092 IHC-P Image

IHC-P analysis of mouse ovary tissue using GTX15092 SCP3 antibody.

Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092

GTX15092 ICC/IF Image

The data was published in the journal J Cell Mol Med in 2018.PMID: 30055035

Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092

GTX15092 ICC/IF Image

The data was published in the journal J Cell Mol Med in 2018.PMID: 30055035

Anti-SCP3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15092

GTX15092 ICC/IF Image

The data was published in the journal J Cell Mol Med in 2018.PMID: 30055035

REFERENCE

Application Reference

Guo K et al. J Cell Mol Med 2018; 22 (10) : 4863-4874 Ablation of Ggnbp2 impairs meiotic DNA double-strand break repair during spermatogenesis in mice.
Yabuta Y et al. J Cell Biol 2011; 192 (5) : 781-95 TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice.
Application : IHC
Reactivity : Mouse
Liang Y et al. PLoS Genet 2010; 6 (1) : e1000826 BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.
Application : ICC/IF
Reactivity : Mouse
Otsuka S et al. Biol Reprod 2008; 79 (1) : 43359 Oocytes in newborn MRL mouse testes.
Application : IHC
Reactivity : Mouse
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 419