APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
| Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human FANCC (NP_000127.2).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
FA complementation group C , FA3 , FAC , FACC
Cellular Localization
Nucleus,Cytoplasm
Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX53977 WB Image
WB analysis of various lysates using GTX53977 FANCC antibody.
Loading : 25 μg
Dilution : 1:1000
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GTX53977 ICC/IF Image
ICC/IF analysis of NIH-3T3 cells using GTX53977 FANCC antibody.
Red : Primary antibody
Blue : DAPI
Dilution : 1:100
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GTX53977 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX53977 FANCC antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:100
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GTX53977 IHC-P Image
IHC-P analysis of human liver cancer tissue using GTX53977 FANCC antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:100
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GTX53977 IHC-P Image
IHC-P analysis of rat testis tissue using GTX53977 FANCC antibody.
Antigen retrieval : 10 mM citrate buffer (pH 6.0)
Dilution : 1:100
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REFERENCE
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REVIEW
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