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G6PC antibody, N-term

Anti-G6PC antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46748
Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748
Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748

Cat. No. GTX46748

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μg ($419)
See all G6PC products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

human fetal lung , MCF-7

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human G6PC

Purification

Affinity Purified

Conjugation

Unconjugated

RRID

AB_11172680

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

glucose-6-phosphatase catalytic subunit , G6PC1 , G6PT , G6Pase , GSD1 , GSD1a

Background

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-G6PC antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46748

GTX46748 IHC-P Image

IHC-P analysis of human kidney tissue using GTX46748 G6PC antibody at 5μg/ml.

Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748

GTX46748 WB Image

WB analysis of human fetal lung tissue using GTX46748 G6PC antibody at 1μg/ml.

Anti-G6PC antibody, N-term used in Western Blot (WB). GTX46748

GTX46748 WB Image

WB analysis of MCF-7 cells using GTX46748 G6PC antibody at 1μg/ml.

REFERENCE

Application Reference

Huang JY et al. RNA 2015; 21 (3) : 385-400 MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1α and PPARγ.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419