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ABCG2 antibody

Anti-ABCG2 antibody used in Western Blot (WB). GTX12131

Cat. No. GTX12131

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse, Rat
Package
100 μg ($439)
See all ABCG2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA

Preservative

0.025% Thimerosal, 0.025% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of mouse BCRP/ABCG2(152-167aa KNHEKNERINTIIKEL), different from the related rat sequence by one amino acid.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2885560

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , AI428558 , BCRP , Bcrp1 , MXR , MXR1

Cellular Localization

Cell membrane

Background

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-ABCG2 antibody used in Western Blot (WB). GTX12131

GTX12131 WB Image

WB analysis of various samples using GTX12131 ABCG2 antibody.
Lane 1 : rat liver tissue lysate at 50ug
Lane 2 : rat spleen tissue lysate at 50ug
Lane 3 : rat kidney tissue lysate at 50ug
Lane 4 : mouse spleen tissue lysate at 50ug
Dilution : 0.5 μg/mL

REFERENCE

Application Reference

Liao WL et al. Int J Mol Sci 2022; 24 (1) Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2.
Garcia-Arroyo FE et al. PLoS One 2018; 13 (8) : e0202901 Probiotic supplements prevented oxonic acid-induced hyperuricemia and renal damage.
Application : WB
Reactivity : Rat
Rosen MB et al. Birth Defects Res 2017; (Epub) ATP Binding Cassette Sub-family Member 2 (ABCG2) and Xenobiotic Exposure During Early Mouse Embryonic Stem Cell Differentiation.
Reactivity : Mouse
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SDS
Sodium Azide.pdf
Thimerosal.pdf
Package List Price ($)
$ 439