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ITGB1BP2 antibody, N-term

Anti-ITGB1BP2 antibody, N-term used in Western Blot (WB). GTX47041
Anti-ITGB1BP2 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47041

Cat. No. GTX47041

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all ITGB1BP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Positive Control

human heart

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human ITGB1BP2

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11167672

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 1 binding protein 2 , CHORDC3 , ITGB1BP , MELUSIN , MSTP015

Background

This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. [provided by RefSeq, May 2017]

Database

Research Area

DATA IMAGES

Anti-ITGB1BP2 antibody, N-term used in Western Blot (WB). GTX47041

GTX47041 WB Image

WB analysis of human heart tissue using GTX47041 ITGB1BP2 antibody at 2.5μg/ml.

Anti-ITGB1BP2 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47041

GTX47041 IHC-P Image

IHC-P analysis of human muscle tissue using GTX47041 ITGB1BP2 antibody at 4.0-8.0μg/ml.

REFERENCE

Application Reference

Jung KI et al. Free Radic Biol Med 2019; 135 : 293-305 Endoplasmic reticulum-associated degradation potentiates the infectivity of influenza A virus by regulating the host redox state.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399