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PGCD antibody

Anti-PGCD antibody used in IHC (Paraffin sections) (IHC-P). GTX14786
Anti-PGCD antibody used in IHC (Paraffin sections) (IHC-P). GTX14786
Anti-PGCD antibody used in Western Blot (WB). GTX14786

Cat. No. GTX14786

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ELISA

Reactivity

 Human, Mouse, Rat, Baboon
Package
50 μg ($399)
See all PGCD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF 1:200
IHC-P Assay dependent
IP 1:200
ELISA 1:10000
Not tested in other applications.

Calculated MW

120 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.75-1.20 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase D protein.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

guanylate cyclase 2D, retinal , CACD1 , CORD5 , CORD6 , CYGD , GUC1A4 , GUC2D , LCA , LCA1 , RCD2 , RETGC-1 , ROS-GC1 , ROSGC , retGC

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]

Database

DATA IMAGES

Anti-PGCD antibody used in IHC (Paraffin sections) (IHC-P). GTX14786

GTX14786 IHC-P Image

IHC-P analysis of baboon small intestine tissue using GTX14786 PGCD antibody.
Dilution : 1:100

Anti-PGCD antibody used in IHC (Paraffin sections) (IHC-P). GTX14786

GTX14786 IHC-P Image

IHC-P analysis of baboon small intestine tissue using GTX14786 PGCD antibody.
Dilution : 1:100

Anti-PGCD antibody used in Western Blot (WB). GTX14786

GTX14786 WB Image

WB analysis of PGCD recombinant protein using GTX14786 PGCD antibody.
Dilution : 1:500

REFERENCE

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REVIEW

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Package List Price ($)
$ 399