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Heparin Cofactor II antibody

Anti-Heparin Cofactor II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87285
Anti-Heparin Cofactor II antibody used in IHC (Paraffin sections) (IHC-P). GTX87285

Cat. No. GTX87285

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all Heparin Cofactor II products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100~1:500
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II (41-90).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

D22S673 , HC2 , HCF2 , HCII , HLS2 , LS2 , SERPIND1 , THPH10 , serpin family D member 1 , Heparin Cofactor II , serpin peptidase inhibitor, clade D (heparin cofactor), member 1

Background

This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015]

Database

Research Area

DATA IMAGES

Anti-Heparin Cofactor II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87285

GTX87285 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX87285 Heparin Cofactor II antibody. The picture on the right is blocked with the synthesized peptide.

Anti-Heparin Cofactor II antibody used in IHC (Paraffin sections) (IHC-P). GTX87285

GTX87285 IHC-P Image

IHC-P analysis of human liver carcinoma tissue using GTX87285 Heparin Cofactor II antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399