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ERVWE1 antibody, N-term

Anti-ERVWE1 antibody, N-term used in Western Blot (WB). GTX46373

Cat. No. GTX46373

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Hamster
Package
50 μg ($409)
See all ERVWE1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic peptide

Purification

Peptide Affinity Purified

Conjugation

Unconjugated

RRID

AB_11172377

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

endogenous retrovirus group W member 1, envelope , ENV , ENVW , ERVWE1 , HERV-7q , HERV-W-ENV , HERV7Q , HERVW , HERVWENV

Background

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-ERVWE1 antibody, N-term used in Western Blot (WB). GTX46373

GTX46373 WB Image

Detection of ERVWE1 in MCF7 using anti-ERVWE1 antibody (GTX46373) at 1 μg/mL.

REFERENCE

Application Reference

Huang Q et al. Cell Mol Life Sci 2014; Reduced syncytin-1 expression in choriocarcinoma BeWo cells activates the calpain1-AIF-mediated apoptosis, implication for preeclampsia.
Application : WB
Reactivity : Human
Huang Q et al. Cell Signal 2013; 25 (4) : 1027-35 Syncytin-1 modulates placental trophoblast cell proliferation by promoting G1/S transition.
Application : WB
Reactivity : Human, Hamster
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 409