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TICAM2 antibody

Anti-TICAM2 antibody used in Western Blot (WB). GTX112785
Anti-TICAM2 antibody used in IHC (Paraffin sections) (IHC-P). GTX112785

Cat. No. GTX112785

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all TICAM2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF Assay dependent
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

Positive Control

HCT116

Predict Reactivity

Bovine, Pig, Chimpanzee, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.72 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human TICAM2 Recombinant protein.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11178647

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll like receptor adaptor molecule 2 , MyD88-4 , TICAM-2 , TIRAP3 , TIRP , TRAM

Cellular Localization

Cytoplasm , Golgi apparatus , Cell membrane

Background

TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030).[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-TICAM2 antibody used in Western Blot (WB). GTX112785

GTX112785 WB Image

Sample (30 ug of whole cell lysate)
A: HCT116
12% SDS PAGE
GTX112785 diluted at 1:1000

Anti-TICAM2 antibody used in IHC (Paraffin sections) (IHC-P). GTX112785

GTX112785 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using TICAM2(GTX112785) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

REFERENCE

Application Reference

KE Nilsen et al. Life Sci Alliance 2023; Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo
Application : ICC/IF
Yurchenko M et al. J Cell Biol 2018; (Epub) SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169