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LMX1A antibody

Anti-LMX1A antibody used in Western Blot (WB). GTX31507
Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507
Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507
Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507
Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507

Cat. No. GTX31507

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all LMX1A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Rat Brain Tissue Lysate(GTX27942)

Product Note

At least two isoforms are known to exist. This antibody is predicted to not cross-react with LMX1B.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Rabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A.The immunogen is located within amino acids 300 - 350 of LMX1A.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

LIM homeobox transcription factor 1 alpha , LMX1 , LMX1.1

Cellular Localization

Nucleus

Background

This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Database

Research Area

DATA IMAGES

Anti-LMX1A antibody used in Western Blot (WB). GTX31507

GTX31507 WB Image

WB analysis of rat brain tissue lysate using GTX31507 LMX1A antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507

GTX31507 IHC-P Image

IHC-P analysis of human brain tissue using GTX31507 LMX1A antibody.
Working concentration : 2.5 μg/ml

Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507

GTX31507 IHC-P Image

IHC-P analysis of human brain tissue using GTX31507 LMX1A antibody.
Working concentration : 20 μg/ml

Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507

GTX31507 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31507 LMX1A antibody.
Working concentration : 20 μg/ml

Anti-LMX1A antibody used in IHC (Paraffin sections) (IHC-P). GTX31507

GTX31507 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31507 LMX1A antibody.
Working concentration : 5 μg/ml

REFERENCE

Application Reference

Ji X et al. Int J Mol Sci 2023; 24 (13) Cerebral-Organoid-Derived Exosomes Alleviate Oxidative Stress and Promote LMX1A-Dependent Dopaminergic Differentiation.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399