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S-arrestin antibody [PDS-1]

Cat. No. GTX40621

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 PDS-1

Isotype

 IgG1

Application

 WB, IHC-Fr

Reactivity

 Human, Rat, Bovine, Pig
Package
50 μl ($399)
See all S-arrestin products

APPLICATION

Application Note

Recommended Starting Dilutions:
For IHC: Use at 1:100
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

45 kDa. ( Note )

Product Note

S-arrestin in retina from porcine, human, bovine & weakly with rat, and shows heteroclitic behaviour

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Pig

Immunogen

Porcine S-antigen

Purification

Protein G

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

S-antigen visual arrestin , RP47 , S-AG

Cellular Localization

Membrane

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399