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5-HT7 receptor antibody

Anti-5-HT7 receptor antibody used in Western Blot (WB). GTX13898

Cat. No. GTX13898

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse, Rat, Dog
Package
100 μg ($419)
See all 5-HT7 receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/ml
ICC/IF 1:10 - 1:2000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Product Note

This sequence is identical for 5-HT7R splice variants in the rat (5-HT7Ra/b/c), human (5-HT7Ra/b/d) and human 5-HT7, the mouse 5-HT7R. It is 93% conserved with dog 5-HT7Ra/b, and 81% conserved with pig 5-HT7R. The 5HT7 antibody recognizes all described 5HT7 receptor splice variants.

Predict Reactivity

Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

This antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 13-28 of the rat 5-HT7R (AAA42134.1).

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled , 5Ht7

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

receptor for 5-hydroxytryptamine; involved in modulatory action on cerebellar function [RGD]

Database

Research Area

DATA IMAGES

Anti-5-HT7 receptor antibody used in Western Blot (WB). GTX13898

GTX13898 WB Image

WB analysis of (A) human brain, (B) mouse brain, (C) rat brain, and (D) human SK-N-SH lysate using GTX13898 5-HT7 receptor antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419