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NIS antibody

Anti-NIS antibody used in IHC (Frozen sections) (IHC-Fr). GTX37599
Anti-NIS antibody used in IHC (Paraffin sections) (IHC-P). GTX37599
Anti-NIS antibody used in IHC (Paraffin sections) (IHC-P). GTX37599
Anti-NIS antibody used in IHC (Paraffin sections) (IHC-P). GTX37599
Anti-NIS antibody used in Western Blot (WB). GTX37599

Cat. No. GTX37599

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr, IHC

Reactivity

 Human, Rat
Package
100 μg ($399)
See all NIS products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-2000
IHC-P 1:400-800
IHC-Fr Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 535-608 amino acids of human NIS

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11174234

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 5 member 5 , NIS , TDH1

Cellular Localization

Membrane; Multi-pass membrane protein

Background

This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-NIS antibody used in IHC (Frozen sections) (IHC-Fr). GTX37599

GTX37599 IHC-Fr Image

IHC-Fr analysis of human thyroid tissue using GTX37599 NIS antibody.
Dilution : 1:200

Anti-NIS antibody used in IHC (Paraffin sections) (IHC-P). GTX37599

GTX37599 IHC-P Image

IHC-P analysis of rat thyroid gland tissue using GTX37599 NIS antibody.

Anti-NIS antibody used in IHC (Paraffin sections) (IHC-P). GTX37599

GTX37599 IHC-P Image

IHC-P analysis of rat thyroid gland tissue using GTX37599 NIS antibody.

Anti-NIS antibody used in IHC (Paraffin sections) (IHC-P). GTX37599

GTX37599 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37599 NIS antibody.
Dilution : 1:200

Anti-NIS antibody used in Western Blot (WB). GTX37599

GTX37599 WB Image

WB analysis of rat brain (Lane 1) and rat kidney (Lane 2) tissue lysates using GTX37599 NIS antibody.
Dilution : 1:200

REFERENCE

Application Reference

Kaushik N et al. Cell Commun Signal 2019; 17 (1) : 12 Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation.
De Rose F et al. J Nucl Med 2018; (Epub) Galectin-3 targeting in thyroid orthotopic tumors opens new ways to characterize thyroid cancer.
Yildirim-Poyraz N et al. Ann Nucl Med 2013; 27 (8) : 786-90 False-positive iodine-131 whole body scan due to a benign dermal lesion; intradermal nevus ((131)I uptake in a benign nevus).
Application : IHC
Reactivity : Human
Submit a Reference

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399