TDO2 antibody [OTI2A4]

Cat. No. GTX04090

Host	Mouse
Clonality	Monoclonal
Clone Name	OTI2A4
Isotype	IgG1
Application	WB, IHC-P
Reactivity	Human, Mouse, Rat
Package	100 μl ($529)

See all TDO2 products

Datasheet

View product citations for antibody GTX04090 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:2000
IHC-P	1:50

Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human TDO2(NP_005642) produced in HEK293T cell.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tryptophan 2,3-dioxygenase , HYPTRP , TDO , TO , TPH2 , TRPO

Background

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]

Database

Gene ID: 6999 TDO2
UniProt: P48775 TDO2

Research Area

DATA IMAGES

GTX04090 IHC-P Image

IHC-P analysis of human liver tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human breast tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human tonsil tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 WB Image

WB analysis of 293T cells transfected with human TDO2 using GTX04090 TDO2 antibody [OTI2A4].
Lane 1 : 293T cells transfected with control vector
Lane 2 : 293T cells transfected with human TDO2
Loading : 5 μg per lane

GTX04090 IHC-P Image

IHC-P analysis of human pancreas tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human colon tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human prostate tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human endometrium adenocarcinoma tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human ovary adenocarcinoma tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

GTX04090 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using TDO2 antibody [OTI2A4].
Antigen retrieval : 10mM citric buffer, pH 6.0, 100ºC for 10min

REFERENCE

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REVIEW

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Package

List Price ($)

100 μl

$ 529

Qty

TDO2 antibody [OTI2A4]

Cat. No. GTX04090

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Calculated MW

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

Note

TARGET

Synonyms

Background

Database

Research Area

DATA IMAGES

GTX04090 IHC-P Image

GTX04090 IHC-P Image

GTX04090 IHC-P Image

GTX04090 WB Image

GTX04090 IHC-P Image

GTX04090 IHC-P Image

GTX04090 IHC-P Image

GTX04090 IHC-P Image

GTX04090 IHC-P Image

GTX04090 IHC-P Image

REFERENCE

REVIEW

Product

Research

Support

Company

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All products are for research use only—Not for use in diagnostic or therapeutic applications.