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THBS4 antibody

Anti-THBS4 antibody used in IHC (Paraffin sections) (IHC-P). GTX87694

Cat. No. GTX87694

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($409)
See all THBS4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human THBS4 (561-610).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

RRID

AB_10724631

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

THBS4 , TSP4 , thrombospondin 4 , Thrombospondin 4

Cellular Localization

Endoplasmic reticulum,Sarcoplasmic reticulum,Secreted,Secreted,Extracellular space,Secreted,Extracellular space,Extracellular matrix

Background

The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Database

Research Area

DATA IMAGES

Anti-THBS4 antibody used in IHC (Paraffin sections) (IHC-P). GTX87694

GTX87694 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX87694 THBS4 antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

Application Reference

Pous L et al. Nat Commun 2020; 11 (1) : 630 Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling.
Application : IHC-P
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409