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Cav1.1 antibody [N2N3]

Anti-Cav1.1 antibody [N2N3] used in IHC (Paraffin sections) (IHC-P). GTX102941
Anti-Cav1.1 antibody [N2N3] used in Western Blot (WB). GTX102941

Cat. No. GTX102941

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all Cav1.1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

212 kDa. ( Note )

Positive Control

293T

Predict Reactivity

Mouse, Rat, Rabbit, Cat, Chicken(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.67 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Cav1.1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2036399

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

calcium voltage-gated channel subunit alpha1 S , CACNL1A3 , CCHL1A3 , Cav1.1 , HOKPP , HOKPP1 , MHS5 , TTPP1 , hypoPP

Cellular Localization

Membrane

Background

This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq]

Database

  • Gene ID: 779 CACNA1S
  • UniProt: Q13698 CACNA1S

Research Area

DATA IMAGES

Anti-Cav1.1 antibody [N2N3] used in IHC (Paraffin sections) (IHC-P). GTX102941

GTX102941 IHC-P Image

Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using CACNA1S(GTX102941) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Anti-Cav1.1 antibody [N2N3] used in Western Blot (WB). GTX102941

GTX102941 WB Image

Sample (30 ug of whole cell lysate)
A: 293T
5% SDS PAGE
GTX102941 diluted at 1:1000

REFERENCE

Application Reference

Thi Do D et al. Cytotechnology 2016; Novel regulations of MEF2-A, MEF2-D, and CACNA1S in the functional incompetence of adipose-derived mesenchymal stem cells by induced indoxyl sulfate in chronic kidney disease.
Application : WB
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169