APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
1:100-1:500 |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Rat B50 brain tumour cell lysate
Product Note
This antibody recognizes the beta isoform (Riz 2) of PRDM 2 (185 kDa) as well as Riz1.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Rat
Immunogen
Purified recombinant GST fusion protein encoding aa 245-573 of rat Riz1 of PRDM2. This antibody also recognizes the isoform beta (Riz2) of PRDM2 (185 kDa).
Purification
Protein A purified, followed by peptide affinity purification.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
PR/SET domain 2 , HUMHOXY1 , KMT8 , KMT8A , MTB-ZF , RIZ , RIZ1 , RIZ2
Cellular Localization
Nucleus
Background
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Database
Research Area
REFERENCE
There are currently no references for PRDM2 antibody (GTX23790). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PRDM2 antibody (GTX23790). Be the first to share your experience with this product.