GeneTex

  • Country / Location Selection

United States (US)

NR1H4 blocking peptide

Cat. No. GTX89181-PEP

Species

 Human
Package
100 μg ($239)

APPLICATION

Product Note

The peptide was used in the production of GTX89181.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

KSCREKTELTPDQQ

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Nuclear Receptor Subfamily 1 Group H Member 4 , Bar , Fxr , Hrr-1 , Hrr1 , Pfic5 , Rip14 , Nr1H4

Background

This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Research Area

REFERENCE

There are currently no references for NR1H4 blocking peptide (GTX89181-PEP). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for NR1H4 blocking peptide (GTX89181-PEP). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 239