GeneTex

  • Country / Location Selection

United States (US)

E2F4 antibody [4E2F04]

Anti-E2F4 antibody [4E2F04] used in Immunohistochemistry (IHC). GTX24071

Cat. No. GTX24071

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4E2F04

Isotype

 IgG1

Application

 IHC-P, IHC-Fr, IHC

Reactivity

 Human, Rat
Package
500 μl ($399)
See all E2F4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P Assay dependent
IHC-Fr Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_370178

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

E2F transcription factor 4 , E2F-4

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-E2F4 antibody [4E2F04] used in Immunohistochemistry (IHC). GTX24071

GTX24071 IHC Image

IHC Image using GTX24071 - Detection of E2F4 by IHC in Human Tonsil

REFERENCE

Application Reference

Molina-Privado I et al. Leukemia 2012; 26 (10) : 2277-85 E2F4 plays a key role in Burkitt lymphoma tumorigenesis.
Application : IHC-P
Submit a Reference

REVIEW

There are currently no reviews for E2F4 antibody [4E2F04] (GTX24071). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399