Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.025% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.4 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide DKDTTRRIHVSTDQD(C) corresponding to amino acid residues 320-335 (Extracellular domain) of human Sortilin (Accession : Q99523).
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
RRID
AB_2887894
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
sortilin 1 , Gp95 , LDLCQ6 , NT3 , NTR3
Cellular Localization
Membrane; Single-pass type I membrane protein,Endoplasmic reticulum membrane,Endosome membrane,Lysosome membrane
Background
This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Database
Research Area