Cancer Stem Cells

Cancer stem cells (CSCs) are increasingly being recognized as the key determinative cells of malignancies. CSCs are described as relatively quiescent cells capable of self-renewal and the generation of more differentiated daughter cells that constitute the bulk of the tumor mass. While there is still debate as to the existence of a single subset of CSCs versus a collection of CSC variants in some tumors, a growing body of literature links CSCs to all steps of tumorigenesis, from initiation to metastasis. Even more ominously, however, evidence suggests that these cells are responsible for therapeutic resistance and relapse, with their persistence often meaning a poor clinical prognosis. For these reasons, CSC biology has become a vigorously studied area of cancer research.

Cancer Stem Cells Markers

Breast	Colon	Glioma	Liver	Lung	Melanoma	Ovarian	Pancreatic	Prostate
ALDH1	ABCB5	A2B5	ALDH1	ABCG2	ABCB5	ALDH1	ABCG2	A2B1
CD24	ALDH1	CD15	CD13	ALDH1	ALDH1	CD24	ALDH1	ALDH1
CD44	CD24	CD90	CD24	CD90	CD20	CD44	CD24	CD24
CD90	CD26	CD133	CD44	CD117	CD34	CD117	CD44	CD44
CD133	CD29	α₆-integrin	CD90	CD133	CD117	CD133	CD133	CD133
α₆-integrin	CD44	Nestin	CD133		CD133		c-Met	CD166
EpCAM	CD133		EpCAM		CD166		CXCR4	α₂β₁-integrin
p63	CD166		ICAM1		CD271		Nestin	α₆-integrin
	EpCAM		Sall4		Nestin		EpCAM
	LGR5

Selected Cancer Stem Cells Markers

ALDH1A1 antibody (GTX123973)

c-Met antibody [C3], C-term (GTX100637)

Integrin beta 1 / CD29 antibody (GTX128839)

CD44 antibody [GT462] (GTX628895)

CD54 / ICAM1 antibody [N1C2](GTX100450)

CD90/Thy1 antibody (GTX130072)

EpCAM antibody [N3C3] (GTX113091)

Nestin antibody [GT623] (GTX630201)

Cat. No.	Product Name	Host & Clonality	Reactivity	Applications
GTX14538	A2B5 antibody [105]	Ms mAb	Hu, Ms, Rat	ICC/IF
GTX60661	ABCB5 antibody [5H3C6]	Ms mAb	Hu	ELISA, FACS, ICC/IF, IHC-P, WB
GTX100437	ABCG2 antibody	Rb pAb	Hu, Ms	IHC-P, WB
GTX23380	ABCG2 antibody [BXP-21]	Ms mAb	Hu	FACS, ICC/IF, IHC-Fr, IHC-P, WB
GTX123973	ALDH1A1 antibody	Rb pAb	Hu, Ms, Rat	ICC/IF, IHC-P, WB
GTX123426	ALDH1A1 antibody	Rb pAb	Hu, Ms, Rat	ICC/IF, IHC-P, WB
GTX123974	ALDH1A1 antibody	Rb pAb	Hu	ICC/IF, IHC-P, WB
GTX100043	ALDH1A1 antibody [C3], C-term	Rb pAb	Hu, Ms	ICC/IF, IHC-P, WB
GTX115148	ALDH1A2 antibody [C1C3]	Rb pAb	Hu, Ms, Rat	IHC-P, WB
GTX115147	ALDH1A2 antibody [N1N3]	Rb pAb	Hu, Ms, Rat	WB
GTX633822	ALDH1A3 antibody [GT926]	Ms mAb	Hu	ICC/IF, WB
GTX110784	ALDH1A3 antibody [N2C2], Internal	Rb pAb	Hu	ICC/IF, IHC-P, WB
GTX32525	c-Kit antibody	Rb pAb	Hu	WB
GTX102788	CD13 antibody	Rb pAb	Hu	IHC-P, WB
GTX42441	CD13 antibody [WM15] (Low endotoxin, azide free)	Ms mAb	Hu, RMK	ELISA, FACS, IHC-Fr, IP, Functional Assay
GTX60471	CD133 antibody [3F10]	Ms mAb	Hu	ELISA, FACS, IHC-P
GTX100567	CD133 antibody [C1C2], Internal	Rb pAb	Hu	FACS, IHC-P, WB
GTX102109	CD133 antibody [N1C1]	Rb pAb	Hu	WB
GTX130098	CD166 antibody	Rb pAb	Hu, Ms, Rat	WB
GTX60782	CD166 antibody [8E12C7]	Ms mAb	Hu	ELISA, FACS, ICC/IF, IHC-P, WB
GTX100209	CD20 antibody [C2C3], C-term	Rb pAb	Hu	ICC/IF, WB
GTX74945	CD24 antibody [SN3]	Ms mAb	Hu, Chmp	FACS, IHC-Fr
GTX84602	CD26 antibody [11D7]	Ms mAb	Hu, Ms	ELISA, FACS, ICC/IF, IHC-P, WB
GTX102262	p75 NGF Receptor / CD271 antibody	Rb pAb	Hu, Ms, Rat	ICC/IF, IHC-Fr, IHC-P, WB
GTX128839	Integrin beta 1 / CD29 antibody	Rb pAb	Hu, Ms, Dog, Rat	ICC/IF, IHC-P, IP, WB
GTX112971	Integrin beta 1 / CD29 antibody	Rb pAb	Hu	ICC/IF, IHC-P, WB
GTX28158	CD34 antibody [MEC14.7]	Rat mAb	Hu, Ms, Rb	ELISA, FACS, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
GTX75411	CD34 antibody [MEC14.7] (FITC)	Rat mAb	Hu, Ms	FACS, ICC/IF, IHC
GTX42057	CD34 antibody [MEC14.7] (Low endotoxin, azide free)	Rat mAb	Hu, Ms	FACS, ICC/IF, IHC, IHC-P, IP
GTX75414	CD34 antibody [MEC14.7] (PE)	Rat mAb	Hu, Ms, Rb	FACS, ICC/IF, IHC
GTX102111	CD44 antibody	Rb pAb	Hu, Ms, Rb	ICC/IF, IHC, IHC-Fr, IHC-P, WB
GTX628895	CD44 antibody [GT462]	Ms mAb	Hu	FACS, IHC-P, WB
GTX628472	CD44 antibody [GT981]	Ms mAb	Hu, Ms	ICC/IF, IHC-P, WB
GTX112893	CD44 antibody [N1N2], N-term	Rb pAb	Hu, Rat	IHC-P, WB
GTX75045	Integrin alpha 6 antibody [450-30A] (FITC)	Ms mAb	Hu, Rb	FACS
GTX100565	Integrin alpha 6 antibody [N3C2], Internal	Rb pAb	Hu, Ms, Rat	ICC/IF, WB
GTX78387	ICAM1 / CD54 antibody [1H4]	Ms mAb	Hu	FACS, ICC/IF, IHC-Fr, IHC-P, WB
GTX100451	ICAM1 / CD54 antibody [C1C3]	Rb pAb	Hu	WB
GTX100450	ICAM1 / CD54 antibody [N1C2]	Rb pAb	Hu	IHC-P, WB
GTX130072	CD90 antibody	Rb pAb	Hu, Ms	IHC-Fr, WB
GTX11153	CD90 antibody [F15-42-1]	Ms mAb	Hu, ClMK	FACS, ICC/IF, IHC-Fr, IP
GTX11155	CD90 antibody [F15-42-1] (FITC)	Ms mAb	Hu, ClMK	FACS, IHC
GTX100637	c-Met antibody [C3], C-term	Rb pAb	Hu	ICC/IF, IP, WB
GTX631993	c-Met antibody [GT1586]	Ms mAb	Hu	IP, WB
GTX631992	c-Met antibody [GT556]	Ms mAb	Hu	IHC-P, IP, WB
GTX22074	CXCR4 antibody	Rb pAb	Hu, Ms	ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB
GTX34705	EpCAM antibody [EGP40/837]	Ms mAb	Hu	FACS, IHC-P
GTX113091	EpCAM antibody [N3C3]	Rb pAb	Hu, Ms	IHC-P, WB
GTX127928	hnRNP A2B1 antibody	Rb pAb	Hu, Ms, Rat	ICC/IF, IHC-P, IP, WB
GTX117578	hnRNP A2B1 antibody	Rb pAb	Hu	ICC/IF, IHC-P, WB
GTX114475	hnRNP A2B1 antibody	Rb pAb	Hu	ICC/IF, IHC-P, WB
GTX631935	LGR5 antibody [GT11312]	Ms mAb	Hu, Ms	WB
GTX133111	Nestin antibody	Rb pAb	Hu, Ms, Rat	ICC/IF, WB
GTX630201	Nestin antibody [GT623]	Ms mAb	Hu, Ms	ICC/IF, IHC-P, WB
GTX102425	p63 antibody [N2C1], Internal	Rb pAb	Hu, Ms, Rat	ICC/IF, IHC-Fr, IHC-P, IP, WB, PLA
GTX633818	p63 antibody [GT1179]	Ms mAb	Hu	ICC/IF, IHC-P, WB
GTX109983	SALL4 antibody [C1C2], Internal	Rb pAb	Hu, Ms, Pig	ICC/IF, IHC-P, WB