Annexin A1 antibody
|Applications||ICC/IF, IHC-P, IP, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||39 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , Molt-4 , NIH-3T3 , JC|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||annexin A1|
|Product Description||Rabbit Polyclonal antibody to Annexin A1 (annexin A1)|
|Background|| Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity. [provided by RefSeq]|
|Synonyms||ANX1 antibody, LPC1 antibody, ANXA1 antibody, calpactin-2 antibody, chromobindin-9 antibody, annexin-1 antibody, phospholipase A2 inhibitory protein antibody, calpactin II antibody, lipocortin I antibody, annexin I (lipocortin I) antibody, annexin A1 antibody, p35 antibody|
|Cellular Localization||Nucleus , Cytoplasm , Cell projection , cilium , Basolateral cell membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Annexin A1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Rabbit, Chimpanzee, Bovine|
|Predict Reactivity Note||Dog (91%), Pig (88%), Rabbit (91%), Chimpanzee (100%), Bovine (90%)|