Caspase 12 antibody

Name: Caspase 12 antibody
Brand: GeneTex
SKU: GTX132298
Price: 399.00 USD
Rating: 4 (1 reviews)

Anti-Caspase 12 antibody used in Western Blot (WB). GTX132298

Cat. No. GTX132298

Reference 5

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Human, Mouse
Package	100 μl ($399), 25 μl ($169)

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View product citations for antibody GTX132298 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000

Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Positive Control

293T , A431 , HeLa , HepG2

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.13 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caspase 12. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2886601

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caspase 12 (gene/pseudogene) , CASP-12 , CASP12P1

Database

Gene ID: 100506742 CASP12
UniProt: Q6UXS9 CASP12

Research Area

DATA IMAGES

GTX132298 WB Image

Untreated (–) and treated (+) HepG2 whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Caspase 12 antibody (GTX132298) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The observed M.W. is based on the publication: PMID: 17122150

GTX132298 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Caspase 12 antibody (GTX132298) diluted at 1:1000.

GTX132298 WB Image

The data was published in the journal Biomed Res Int in 2020. PMID: 32071920

REFERENCE

Application Reference

Bhattarai KR et al. Redox Biol 2021; 47 : 102128 TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans.

Application : WB

Reactivity : Human

Zhang R et al. J Cell Mol Med 2020; 24 (11) : 6028-6042 Dehydrocostus lactone inhibits cell proliferation and induces apoptosis by PI3K/Akt/Bad and ERS signalling pathway in human laryngeal carcinoma.

Zhang R et al. Biomed Res Int 2020; 2020 : 7643248 Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells.

Huang CY et al. Nutrients 2020; 12 (6) Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/Akt/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy.

Application : WB

Reactivity : Mouse

Chen Y et al. Biosci Rep 2018; 38 (5) gandouling combined with * improves cerebrovascular injury via perk/eif2α/chop endoplasmic reticulum stress pathway in the mouse model of wilson's disease.

Application : WB

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