|Full Name||protein tyrosine kinase 2|
|Product Description||Rabbit Polyclonal antibody to FAK (phospho Tyr576) (protein tyrosine kinase 2)|
|Background||This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq]|
|Synonyms||PPP1R71 Antibody , FADK Antibody , protein tyrosine kinase 2 Antibody , pp125FAK Antibody , PTK2 Antibody , FAK Antibody , FRNK Antibody , FAK1 Antibody , p125FAK Antibody|
|Cellular Localization||Cell junction , focal adhesion , Cell membrane; Peripheral membrane protein; Cytoplasmic side |
|Target||FAK (phospho Tyr576)|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Human FAK (phospho Tyr576). The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Chicken (100%)|