|Full Name||glucose-6-phosphate isomerase|
|Product Description||Rabbit Polyclonal antibody to GPI (glucose-6-phosphate isomerase)|
|Background||This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq]|
|Synonyms||AMF antibody, DKFZp686C13233 antibody, GNPI antibody, NLK antibody, PGI antibody, PHI antibody, SA-36 antibody, SA36 antibody, GPI antibody, phosphosaccharomutase antibody, neuroleukin antibody, autocrine motility factor antibody, sperm antigen 36 antibody, hexosephosphate isomerase antibody, phosphohexomutase antibody, phosphohexose isomerase antibody, oxoisomerase antibody, glucose-6-phosphate isomerase antibody, hexose monophosphate isomerase antibody, sperm antigen-36 antibody, phosphoglucose isomerase antibody, glucose phosphate isomerase antibody|
|Cellular Localization||Cytoplasm , Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human GPI. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Xenopus laevis, Pig, Rabbit, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (89%), Xenopus laevis (81%), Pig (92%), Rabbit (92%), Chicken (86%), Chimpanzee (99%), Bovine (90%)|