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PDE4B3 antibody

Overexpression
Anti-PDE4B3 antibody used in Western Blot (WB). GTX14615
Anti-PDE4B3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX14615

Cat. No. GTX14615

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IP, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($409)
See all PDE4B3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF Assay dependent
IP 1:200
ELISA 1:10000
Not tested in other applications.

Calculated MW

83 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic peptide selective only for PDE4B3 subtype.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

phosphodiesterase 4B , DPDE4 , PDEIVB

Background

This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

Database

Research Area

DATA IMAGES

Anti-PDE4B3 antibody used in Western Blot (WB). GTX14615

GTX14615 WB Image

Overexpression

WB analysis of PDE4B3 transfected COS1 cell lysate using GTX14615 PDE4B3 antibody.

Anti-PDE4B3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX14615

GTX14615 ICC/IF Image

ICC/IF analysis of PDE4B3 transfected COS1 cells using GTX14615 PDE4B3 antibody.

REFERENCE

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REVIEW

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Package List Price ($)
$ 409