APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:1000-1:3000 |
| 1:100-1:500 |
| 1:50-1:200 |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rabbit, Bovine, Dog, Chicken, Pig, Xenopus laevis, Horse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthesized peptide derived from human DRP1 around the phosphorylation site of Ser637.
Purification
Purified by sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
From serum
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
dynamin 1 like , DLP1 , DRP1 , DVLP , DYMPLE , EMPF , EMPF1 , HDYNIV , OPA5
Cellular Localization
Cytoplasm, cytosol , Golgi apparatus , Mitochondrion outer membrane
Background
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Database
Research Area
DATA IMAGES
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GTX01567 IHC-P Image
IHC-P analysis of human liver carcinoma tissue section using GTX01567 DRP1 (phospho Ser637) antibody.
Antigen retireval : Heat mediated antigen retrieval step in citrate buffer
Dilution : 1:100
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GTX01567 WB Image
WB analysis of 293 whole cell lysate using GTX01567 DRP1 (phospho Ser637) antibody.
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GTX01567 IHC-P Image
IHC-P analysis of human pancreatic cancer tissue using GTX01567 DRP1 (phospho Ser637) antibody.
Antigen retireval : Heat mediated antigen retrieval step in citrate buffer
Dilution : 1:100
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GTX01567 ICC/IF Image
ICC/IF analysis of PFA-fixed NCI-H1299 cells using GTX01567 DRP1 (phospho Ser637) antibody.
Permeabilized : 0.1% saponin
Dilution : 1:200
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GTX01567 ELISA Image
ELISA analysis of phospho- and non phosho- immunogen peptide using GTX01567 DRP1 (phospho Ser637) antibody.
P-peptide : phospho-peptide
N-peptide : non-phospho-peptide
Peptides concentration : 1μg/ml
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GTX01567 WB Image
WB analysis of 293 whole cell lysate using GTX01567 DRP1 (phospho Ser637) antibody.
Lane 1 : Primary antibody pre-incubated with phospho-blocking peptide
Lane 2 : Primary antibody pre-incubated with non-phospho-blocking peptide
Lane 3 : untreated sample
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GTX01567 IHC-P Image
IHC-P analysis of human normal tissue adjacent to pancreatic cancer using GTX01567 DRP1 (phospho Ser637) antibody.
Antigen retireval : Heat mediated antigen retrieval step in citrate buffer
Dilution : 1:100
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REFERENCE
There are currently no references for DRP1 (phospho Ser637) antibody (GTX01567). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for DRP1 (phospho Ser637) antibody (GTX01567). Be the first to share your experience with this product.
