DRP1 (phospho Ser637) antibody

Cat. No. GTX03497

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB
Reactivity	Mouse
Package	100 μl ($409)

See all DRP1 products

Datasheet

View product citations for antibody GTX03497 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:2000

Not tested in other applications.

Calculated MW

82 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic phosphorylated peptide around S637 of human DRP1 (NP_036192.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynamin 1 like , DLP1 , DRP1 , DVLP , DYMPLE , EMPF , EMPF1 , HDYNIV , OPA5

Cellular Localization

Cytoplasm, cytosol , Golgi apparatus , Mitochondrion outer membrane

Background

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Database

Gene ID: 10059 DNM1L
UniProt: O00429 DNM1L

Research Area

DATA IMAGES

GTX03497 WB Image

WB analysis of NIH/3T3 cell treated with Forskolin (30 uM) at 37ºC for 30 minutes after serum-starvation overnight lysate using GTX03497 DRP1 (phospho Ser637) antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit.
Dilution : 1:500
Loading : 25 μg per lane

REFERENCE

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REVIEW

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Package

List Price ($)

100 μl

$ 409

Qty