|Full Name||transforming growth factor, beta 1|
|Product Description||Rabbit Polyclonal antibody to TGF beta 1 (transforming growth factor, beta 1)|
|Background||TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM]|
|Synonyms||CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGFB1 antibody, TGF-beta 1 protein antibody, TGF-beta-1 antibody, transforming growth factor beta-1 antibody, latency-associated peptide antibody, transforming growth factor, beta 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human TGF beta 1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Pig, Sheep, Bovine, Guinea pig|
|Predict Reactivity Note||Dog (92%), Pig (91%), Sheep (91%), Bovine (92%), Guinea pig (85%)|