|Full Name||met proto-oncogene (hepatocyte growth factor receptor)|
|Product Description||Mouse Monoclonal antibody [GT1586] to c-Met (met proto-oncogene (hepatocyte growth factor receptor))|
|Background||The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||c-Met Antibody , RCCP2 Antibody , AUTS9 Antibody , met proto-oncogene (hepatocyte growth factor receptor) Antibody , HGFR Antibody|
|Cellular Localization||Membrane; Single-pass type I membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human c-Met. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%)|