0.01M PBS, 50% glycerol, 0.05% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
~1 mg/ml (Please refer to the vial label for the specific concentration.)
synthetic peptide corresponding to the propeptide domain of human ADAM-19.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ADAM metallopeptidase domain 19 , FKSG34 , MADDAM , MLTNB
Membrane; Single-pass type I membrane protein
ADAM19, is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. It has been cloned from mouse and human. ADAM19 was first described in muscle cells as a protein with homology to the fertilins (ADAMs 1 and 2). Initial observations indicated a role for ADAM19 in myoblast fusion, similar to sperm-egg fusion aided by ADAMs 1 and 2. ADAM19 may be important in osteoblast differentiation, as a marker for dendritic cell differentiation, and in the intracellular processing of neuregulin. The ADAMs proteins are structurally similar, possessing a signal sequence, metalloprotease domain (inactive in some ADAMs), disintegrin domain, cysteinrich domain, EGF-like repeat, type-I transmembrane domain, and cytoplasmic domain.