GeneTex
Events
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Meeting - The 19th GPCR meeting
2025/6/27 - 2025/6/28
Shimadzu Tokyo Innovation Plaza (神奈川県 川崎市)
Kawasaki, Japan -
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Webinar - Immunomodulation by Food to Maintain Gastrointestinal Health
Thursday, February 13, 2025 at 10:00 a.m. (EST)
Speaker: Huub F.J. Savelkoul, Ph.D.,
Professor of Cell Biology and Immunology Wageningen University and Research, Wageningen, The Netherlands
Dr. H.F.J. Savelkoul earned his Ph.D. in the Department of Immunology from the distinguished Erasmus University in Rotterdam in the Benner lab. He then completed a postdoctoral fellowship in the Coffman lab at the DNAX Research Institute of Molecular and Cellular Biology in Palo Alto, California. This was followed by appointments as an Assistant, then Associate, Professor in the Immunology Department at Erasmus University. He subsequently accepted a position as a Full Professor in Cell Biology and Immunology at Wageningen University and Research in Wageningen, The Netherlands. Dr. Savelkoul has attained success in all aspects of his scientific career, including supporting a highly productive lab that generated almost 400 peer-reviewed publications that focus on diverse aspects of the interaction between food and the immune system, immunochemistry, and immunodiagnostics. In addition, he co-edited several books, trained well over 50 Ph.D. candidates, is named on eight patents, and received multiple awards that include recognition as an outstanding teacher. He is also a member of many prestigious societies and organizations focused on immunology, including the Netherlands Society for Immunology, the European Academy for Allergy and Clinical Immunology, and the Dutch Foundation for Asthma Prevention. -
Webinar - Viral and Host Determinants of Arbovirus Viremia and Dissemination
Thursday, Nov 29, 2023 at 11:00 a.m. (EST)
Speaker: Thomas E. "TEM" Morrison, PhD
Arboviruses are major public health threats. Major determinants of arbovirus transmission, geographic spread and pathogenesis are the magnitude and duration of viremia in the vertebrate host. However, the factors that dictate viremia following arbovirus infection are poorly defined. Dr. Morrison’s team used mouse models to find that a panel of arboviruses display distinct clearance kinetics from the circulation. Moreover, for several different alphaviruses, bunyaviruses, and flaviviruses, they discovered that clearance requires blood-exposed liver Kupffer cells. However, while the clearance of dengue virus (DENV) and eastern equine encephalitis virus (EEEV) also requires Kupffer cells, distinct pathways including mannose binding lectin (MBL) and glycosaminoglycans (GAGs), respectively, promote clearance. In his talk, Dr. Morrison will describe the mechanisms underlying these differences, host species specificity, and a previously unrecognized arbovirus-scavenging role for lymphatic endothelial cells. Collectively, his team’s work provides new insight into virus-host interactions that influence arbovirus viremia, dissemination, and pathogenesis.
