APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500 - 1:2000 |
| 1:50 - 1:200 |
| 1:50 - 1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS pH7.3, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant funsion protein containing a sequence corresponding to amino acids 282-581 of human TRIP4 (NP_057297.2).
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
thyroid hormone receptor interactor 4 , ASC-1 , ASC1 , HsT17391 , MDCDC , SMABF1 , ZC2HC5
Cellular Localization
Nucleus,Cytoplasm, cytosol
Background
This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). [provided by RefSeq, Apr 2016]
Database
Research Area
DATA IMAGES
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GTX66364 IP Image
IP analysis of A549 cell lysate using GTX66364 ASC1 antibody.
Antibody amount : 3μg / 200μg lysate
Dilution : 1:1000
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GTX66364 WB Image
WB analysis of various sample lysates using GTX66364 ASC1 antibody.
Dilution : 1:1000
Loading : 25μg per lane
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GTX66364 IHC-P Image
IHC-P analysis of human colon carcinoma tissue using GTX66364 ASC1 antibody.
Dilution : 1:100
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GTX66364 IHC-P Image
IHC-P analysis of human esophageal tissue using GTX66364 ASC1 antibody.
Dilution : 1:100
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GTX66364 IHC-P Image
IHC-P analysis of rat heart tissue using GTX66364 ASC1 antibody.
Dilution : 1:100
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REFERENCE
There are currently no references for ASC1 antibody (GTX66364). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for ASC1 antibody (GTX66364). Be the first to share your experience with this product.
