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ATRIP antibody

Anti-ATRIP antibody used in Immunoprecipitation (IP). GTX14074

Cat No. GTX14074

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IP

Reactivity

Human
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:5000 - 1:15000
IP 3 - 8 μg/mg lysate
Not tested in other applications.

Calculated MW

86 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate pH 7.0 - 8.0, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide derived from a sequence between amino acids 500-550 of human ATRIP [UniProt# Q8WXE1]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_384326

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ATR interacting protein

Cellular Localization

Nucleus

Background

The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-ATRIP antibody used in Immunoprecipitation (IP). GTX14074

GTX14074 IP Image

(A)WB analysis of HeLa and 293T cell lysate using GTX14074 ATRIP antibody.
Dilution : 0.2(left) and 0.1(right) μg/ml
(B)IP analysis of ATRIP recombinant protein using GTX14074 ATRIP antibody.

REFERENCE

REVIEW

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SDS
Sodium Azide.pdf