*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
A431 , mouse kidney
Rat, Bovine, Chicken, Pig(>80% identity)
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human BIN1. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
AMPH2 antibody, AMPHL antibody, DKFZp547F068 antibody, MGC10367 antibody, SH3P9 antibody, BIN1 antibody, box-dependent myc-interacting protein 1 antibody, amphiphysin-like protein antibody, amphiphysin II antibody, box dependant MYC interacting protein 1 antibody, myc box-dependent-interacting protein 1 antibody, bridging integrator 1 antibody
Isoform BIN1: Nucleus , Isoform IIA: Cytoplasm
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq]