Tris-glycine buffer pH7.2-7.4, stabilizing proteins , cryogenic stabilizers, glycerol and 0.02% sodium azide as preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.75 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide - amino acids 31-52 of Human Bestrophin. The peptide was amidated for conjugation.
Affinity purified with antigen
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
BEST, VMD2, Bestrophin, 7439, O76090, 153700, TU15B, BMD
Bestrophin is a 68 kDa basolateral plasma membrane protein encoded by the VMD2 gene. The role of Bestrophin is as yet unclear but it is thought to be involved in Best Macular Dystrophy (BMD) or Vitelliform Macular Dystrophy (VMD2); inherited early onset autosomal forms of macular degeneration. There is evidence to suggest that Bestrophin is a chloride channel that plays a role in generating the altered electrooculogram in Best disease patients.