GeneTex
United States (US)

C4 binding protein B antibody

GTX33051_20180530_IHC-P_1_18121410_838.jpg
GTX33051_20180530_ICCIF_18121410_725.jpg
GTX33051_20180530_IHC-P_18121410_495.jpg
GTX33051_20180530_WB_18121410_948.jpg

Cat No. GTX33051

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

28 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human C4BPB (NP_001017364.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Complement Component 4 Binding Protein Beta,C4Bp,C4Bpb

Background

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX33051_20180530_IHC-P_1_18121410_838.jpg

GTX33051 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX33051 C4 binding protein B antibody.
Dilution : 1:100

GTX33051_20180530_ICCIF_18121410_725.jpg

GTX33051 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX33051 C4 binding protein B antibody.
Blue : DAPI

GTX33051_20180530_IHC-P_18121410_495.jpg

GTX33051 IHC-P Image

IHC-P analysis of human stomach tissue using GTX33051 C4 binding protein B antibody.
Dilution : 1:100

GTX33051_20180530_WB_18121410_948.jpg

GTX33051 WB Image

WB analysis of various samples using GTX33051 C4 binding protein B antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329