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C4 binding protein B antibody

Anti-C4 binding protein B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33051
Anti-C4 binding protein B antibody used in Western Blot (WB). GTX33051
Anti-C4 binding protein B antibody used in IHC (Paraffin sections) (IHC-P). GTX33051
Anti-C4 binding protein B antibody used in IHC (Paraffin sections) (IHC-P). GTX33051

Cat No. GTX33051

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
ICC/IF 1:50-1:100
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human C4BPB (NP_001017364.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

complement component 4 binding protein beta , C4BP

Cellular Localization

Secreted

Background

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-C4 binding protein B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33051

GTX33051 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX33051 C4 binding protein B antibody.
Blue : DAPI

Anti-C4 binding protein B antibody used in Western Blot (WB). GTX33051

GTX33051 WB Image

WB analysis of various sample lysates using GTX33051 C4 binding protein B antibody.
Loading : 25ug per lane
Dilution : 1:1000

Anti-C4 binding protein B antibody used in IHC (Paraffin sections) (IHC-P). GTX33051

GTX33051 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX33051 C4 binding protein B antibody.
Dilution : 1:100

Anti-C4 binding protein B antibody used in IHC (Paraffin sections) (IHC-P). GTX33051

GTX33051 IHC-P Image

IHC-P analysis of human stomach tissue using GTX33051 C4 binding protein B antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329