Form
Liquid
Buffer
2.5% BSA, 0.45% NaCl, 0.1% Na₂HPO₄
Preservative
0.025% Thimerosal, 0.025% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
500 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PROM1(836-850aa MKNMENGNNGYHKDH), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
RRID
AB_2885578
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Cellular Localization
Apical cell membrane,Cell projection,Microvillus membrane,Cell projection,Cilium,Photoreceptor outer segment,Endoplasmic reticulum,Endoplasmic reticulum-Golgi intermediate compartment,Apical cell membrane,Cell projection,Cell projection (by similarity),Cilium (by similarity),Microvillus membrane,Photoreceptor outer segment (by similarity),Apical cell membrane,Cell projection,Cell projection (by similarity),Cilium (by similarity),Microvillus membrane,Photoreceptor outer segment (by similarity),Apical cell membrane,Cell projection,Cell projection (by similarity),Cilium (by similarity),Microvillus membrane,Photoreceptor outer segment (by similarity),Apical cell membrane,Cell projection,Cell projection (by similarity),Cilium (by similarity),Microvillus membrane,Photoreceptor outer segment (by similarity),Apical cell membrane,Cell projection,Cell projection (by similarity),Cilium (by similarity),Microvillus membrane,Photoreceptor outer segment (by similarity)
Background
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Database
Research Area
