GeneTex

  • Country / Location Selection

United States (US)

CD19 antibody [HIB19] (PE-Cy7)

Anti-CD19 antibody [HIB19] (PE-Cy7) used in Flow cytometry (FACS). GTX01455-10

Cat. No. GTX01455-10

Reference 1684

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 HIB19

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
100 test ($259)
See all CD19 products
PRODUCT

Summary

The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS 0.25 μg (5 μl) for 10⁵-10⁸ cells in 100 μl sample per test
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.05 mg/ml (Please refer to the vial label for the specific concentration.)

Purification

Purified by affinity chromatography
From tissue culture supernatant

Conjugation

Phycoerythrin-Cyanine7 (PE-Cy7)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD19 molecule , B4 , CD19 , CVID3

Cellular Localization

Membrane

Background

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-CD19 antibody [HIB19] (PE-Cy7) used in Flow cytometry (FACS). GTX01455-10

GTX01455-10 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX01455-10 CD19 antibody [HIB19] (PE-Cy7).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

REFERENCE

Clone Reference

Benjelloun F et al. Front Immunol 2020; 11:1655 Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings.
Bourdely P et al. Immunity 2020; 53 (2):335-352.e8 Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells.
Salzer B et al. Nat Commun 2020; 11 (1):4166 Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Imura Y et al. JCI Insight 2020; 5 (14) CD19-targeted CAR regulatory T cells suppress B cell pathology without GvHD.
Zhao NQ et al. PLoS One 2020; 15 (9):e0238347 Natural killer cell phenotype is altered in HIV-exposed seronegative women.
Show More +
Submit a Reference

REVIEW

There are currently no reviews for CD19 antibody [HIB19] (PE-Cy7) (GTX01455-10). Be the first to share your experience with this product.
Submit a Review
Clone Reference
Lartey S et al. J Infect Dis 2020; 221 (1):21-32 Live-Attenuated Influenza Vaccine Induces Tonsillar Follicular T Helper Cell Responses That Correlate With Antibody Induction.
Telesford KM et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (1) Black African and Latino/a identity correlates with increased plasmablasts in MS.
Wiedeman AE et al. J Clin Invest 2020; 130 (1):480-490 Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression.
Suzuki D et al. Stem Cell Reports 2020; 14 (1):49-59 iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.
Afreen S et al. Cell Death Dis 2020; 11 (1):8 BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells.
Queckb?rner S et al. Stem Cell Res Ther 2020; 11 (1):15 Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile.
Suzuki T et al. J Clin Invest 2020; 130 (2):799-812 Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections.
Hedlund M et al. RMD Open 2020; 6 (1) Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero.
Gasser P et al. Nat Commun 2020; 11 (1):165 The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab.
Byrne AJ et al. J Exp Med 2020; 217 (3) Dynamics of human monocytes and airway macrophages during healthy aging and after transplant.
Rohner L et al. Sci Rep 2020; 10 (1):222 Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study.
Huhn O et al. Nat Commun 2020; 11 (1):381 Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy.
Yamamoto EA et al. Nutrients 2020; 12 (2) Low Levels of Vitamin D Promote Memory B Cells in Lupus.
Kudryavtsev I et al. Sci Rep 2020; 10 (1):1059 Imbalance in B cell and T Follicular Helper Cell Subsets in Pulmonary Sarcoidosis.
Yang L et al. Genes Dis 2020; 7 (1):128-137 Novel biallelic TRNT1 mutations lead to atypical SIFD and multiple immune defects.
Pilon C et al. Front Immunol 2020; 11:34 Phenotypic and Transcriptomic Lymphocytes Changes in Allograft Recipients After Intravenous Immunoglobulin Therapy in Kidney Transplant Recipients.
Panda SK et al. Proc Natl Acad Sci U S A 2020; 117 (6):3103-3113 IL-4 controls activated neutrophil FcγR2b expression and migration into inflamed joints.
Wilson TJ et al. Immunology 2020; 159 (4):393-403 Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection.
Rendeiro AF et al. Nat Commun 2020; 11 (1):577 Chromatin mapping and single-cell immune profiling define the temporal dynamics of ibrutinib response in CLL.
Marasco M et al. Sci Adv 2020; 6 (5):eaay4458 Molecular mechanism of SHP2 activation by PD-1 stimulation.
Kim KH et al. Oncoimmunology 2020; 9 (1):1722023 Immune-related adverse events are clustered into distinct subtypes by T-cell profiling before and early after anti-PD-1 treatment.
Kim JH et al. Sci Rep 2020; 10 (1):1835 Circulating serum HBsAg level is a biomarker for HBV-specific T and B cell responses in chronic hepatitis B patients.
Kerntke C et al. Front Immunol 2020; 11:118 There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes.
Mirlekar B et al. Cancer Immunol Res 2020; 8 (3):292-308 B cell-Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer.
M?rquez EJ et al. Nat Commun 2020; 11 (1):751 Sexual-dimorphism in human immune system aging.
Schommers P et al. Cell 2020; 180 (3):471-489.e22 Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody.
Lobner E et al. Front Bioeng Biotechnol 2020; 8:49 Getting CD19 Into Shape: Expression of Natively Folded "Difficult-to- Express" CD19 for Staining and Stimulation of CAR-T Cells.
Kunishita Y et al. Front Immunol 2020; 11:98 TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis.
Walker LA et al. J Transl Med 2020; 18 (1):63 CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq.
Sekido Y et al. Sci Rep 2020; 10 (1):2988 Some Gammaproteobacteria are enriched within CD14+ macrophages from intestinal lamina propria of Crohn's disease patients versus mucus.
Moral JA et al. Nature 2020; 579 (7797):130-135 ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunity.
Okurut S et al. Infect Immun 2020; 88 (3) B Cell Compartmentalization in Blood and Cerebrospinal Fluid of HIV-Infected Ugandans with Cryptococcal Meningitis.
Peluso MJ et al. J Virus Erad 2020; 6 (1):19-26 Cerebrospinal fluid soluble CD30 elevation despite suppressive antiretroviral therapy in individuals living with HIV-1.
Nguyen T et al. PLoS Pathog 2020; 16 (2):e1008336 The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication.
?yszkiewicz M et al. Nat Commun 2020; 11 (1):1031 Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells.
Booth JS et al. J Transl Med 2020; 18 (1):102 Oral typhoid vaccine Ty21a elicits antigen-specific resident memory CD4+ T cells in the human terminal ileum lamina propria and epithelial compartments.
Golinski ML et al. Front Immunol 2020; 11:32 CD11c+ B Cells Are Mainly Memory Cells, Precursors of Antibody Secreting Cells in Healthy Donors.
Salomonsson M et al. Front Immunol 2020; 11:321 Localization-Specific Expression of CCR1 and CCR5 by Mast Cell Progenitors.
Rinc?n-Ar?valo H et al. Heliyon 2020; 6 (3):e03441 Low frequency of IL-10+ B cells in patients with atherosclerosis is related with inflammatory condition.
Zhang W et al. Nat Commun 2020; 11 (1):1187 Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy.
Kotaki R et al. Sci Rep 2020; 10 (1):4355 Dasatinib exacerbates splenomegaly of mice inoculated with Epstein-Barr virus-infected lymphoblastoid cell lines.
Smith MA et al. Sci Rep 2020; 10 (1):4462 Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus.
Novice T et al. J Clin Immunol 2020; 40 (2):267-276 A Germline Mutation in the C2 Domain of PLCγ2 Associated with Gain-of-Function Expands the Phenotype for PLCG2-Related Diseases.
Miller SM et al. Front Immunol 2020; 11:406 Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice.
Zeng Q et al. Mediators Inflamm 2020; 2020:4176082 Leptin Regulated ILC2 Cell through the PI3K/AKT Pathway in Allergic Rhinitis.
G?mez-Ch?vez F et al. Front Immunol 2020; 11:390 A Proinflammatory Immune Response Might Determine Toxoplasma gondii Vertical Transmission and Severity of Clinical Features in Congenitally Infected Newborns.
Li Y et al. Front Immunol 2020; 11:448 Distinct Dysfunctional States of Circulating Innate-Like T Cells in Metabolic Disease.
Einhaus J et al. Arthritis Res Ther 2020; 22 (1):66 Inhibition of effector B cells by ibrutinib in systemic sclerosis.
Busse M et al. Front Immunol 2020; 11:386 Regulatory B Cells Are Decreased and Impaired in Their Function in Peripheral Maternal Blood in Pre-term Birth.
Alarcon-Barrera JC et al. Anal Bioanal Chem 2020; 412 (10):2353-2363 Lipid metabolism of leukocytes in the unstimulated and activated states.
Martin E et al. JCI Insight 2020; 5 (5) Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.
Umeda M et al. Sci Rep 2020; 10 (1):6010 Thymus and Activation-regulated Chemokine as a Biomarker for IgG4-related Disease.
Wijesinghe A et al. J Biomed Sci 2020; 27 (1):50 Phenotype and functionality of follicular helper T cells in patients with acute dengue infection.
Wong SW et al. Sci Adv 2020; 6 (15):eaaw0158 Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking.
Shopova IA et al. mBio 2020; 11 (2) Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus.
Anderson EJ et al. Vaccines (Basel) 2020; 8 (1) Plasmablast, Memory B Cell, CD4+ T Cell, and Circulating Follicular Helper T Cell Responses to a Non-Replicating Modified Vaccinia Ankara Vaccine.
Jackson-Jones LH et al. Immunity 2020; 52 (4):700-715.e6 Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants.
M?noret S et al. Transplantation 2020; 104 (4):715-723 In Vivo Analysis of Human Immune Responses in Immunodeficient Rats.
Caduff N et al. PLoS Pathog 2020; 16 (4):e1008477 Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice.
El-Neanaey WA et al. Int J Hematol Oncol Stem Cell Res 2020; 14 (1):27-37 Evaluation of CD160 and CD200 Expression as Differentiating Markers between Chronic Lymphocytic Leukemia and Other Mature B-Cell Neoplasms.
Samassa F et al. Cell Microbiol 2020; 22 (5):e13166 Shigella impairs human T lymphocyte responsiveness by hijacking actin cytoskeleton dynamics and T cell receptor vesicular trafficking.
De Martino M et al. Sci Rep 2020; 10 (1):7057 HMGA1-pseudogene7 transgenic mice develop B cell lymphomas.
Aguiar FS et al. Stem Cell Res Ther 2020; 11 (1):167 Autologous bone marrow-derived mononuclear cell therapy in three patients with severe asthma.
James KR et al. Nat Immunol 2020; 21 (3):343-353 Distinct microbial and immune niches of the human colon.
J Clin Immunol 2020; 40 (Suppl 1):1-163 2020 CIS Annual Meeting: Immune Deficiency & Dysregulation North American Conference.
Ainai A et al. Microbiol Immunol 2020; 64 (4):313-325 Human immune responses elicited by an intranasal inactivated H5 influenza vaccine.
Di Genua C et al. Cancer Cell 2020; 37 (5):690-704.e8 C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.
Tanno H et al. Sci Adv 2020; 6 (17):eaay9093 A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires.
Grifoni A et al. Cell 2020; 181 (7):1489-1501.e15 Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.
Takata K et al. Diabetes Metab Syndr Obes 2020; 13:1491-1497 Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee.
Loff S et al. Mol Ther Oncolytics 2020; 17:408-420 Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia.
Barberi C et al. Blood Adv 2020; 4 (10):2297-2307 Myeloma cells induce the accumulation of activated CD94low NK cells by cell-to-cell contacts involving CD56 molecules.
Zhao NQ et al. Front Immunol 2020; 11:829 Treated HIV Infection Alters Phenotype but Not HIV-Specific Function of Peripheral Blood Natural Killer Cells.
Li Z et al. J Clin Lab Anal 2020; 34 (5):e23155 High-dimensional single-cell proteomics analysis reveals the landscape of immune cells and stem-like cells in renal tumors.
Sun X et al. Nat Commun 2020; 11 (1):2421 Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation.
Sun B et al. Orphanet J Rare Dis 2020; 15 (1):131 LIG4 syndrome: clinical and molecular characterization in a Chinese cohort.
Garner-Spitzer E et al. Front Immunol 2020; 11:860 Obesity and Sex Affect the Immune Responses to Tick-Borne Encephalitis Booster Vaccination.
Roschewski M et al. Sci Immunol 2020; 5 (48) Inhibition of Bruton tyrosine kinase in patients with severe COVID-19.
Ruiz-Aparicio PF et al. Int J Mol Sci 2020; 21 (10) Dual Targeting of Stromal Cell Support and Leukemic Cell Growth by a Peptidic PKC Inhibitor Shows Effectiveness against B-ALL.
Pearson FE et al. Clin Transl Immunology 2020; 9 (6):e1141 Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate na?ve and memory WT1-specific CD8+ T cells.
Gilmore W et al. J Neuroinflammation 2020; 17 (1):189 Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis.
Schwerd T et al. Bone Res 2020; 8:24 A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.
Yan H et al. ACS Appl Mater Interfaces 2020; 12 (17):19324-19336 Glyco-Modification of Mucin Hydrogels to Investigate Their Immune Activity.
Magatti M et al. Front Immunol 2020; 11:1156 B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells.
Wagstaffe HR et al. J Clin Invest 2020; 130 (7):3936-3946 Ebola virus glycoprotein stimulates IL-18-dependent natural killer cell responses.
Bennstein SB et al. Elife 2020; 9 Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells.
Li Z et al. Clin Transl Immunology 2020; 9 (7):e1156 Targeting CD83 in mantle cell lymphoma with anti-human CD83 antibody.
Scharf L et al. J Virol 2020; 94 (14) Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection.
Riese P et al. Vaccines (Basel) 2020; 8 (2) Responsiveness to Influenza Vaccination Correlates with NKG2C-Expression on NK Cells.
Garrido-Martin EM et al. J Immunother Cancer 2020; 8 (2) M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer.
Marzaioli V et al. Front Immunol 2020; 11:1406 Monocyte-Derived Dendritic Cell Differentiation in Inflammatory Arthritis Is Regulated by the JAK/STAT Axis via NADPH Oxidase Regulation.
Hood SP et al. Elife 2020; 9 Identifying prostate cancer and its clinical risk in asymptomatic men using machine learning of high dimensional peripheral blood flow cytometric natural killer cell subset phenotyping data.
Mendes-Frias A et al. J Transl Autoimmun 2020; 3:100056 Dysregulation of glycerophospholipid metabolism during Beh?et's disease contributes to a pro-inflammatory phenotype of circulating monocytes.
Gruber CN et al. Immunity 2020; Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function.
Zhou R et al. Immunity 2020; Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses.
Hu EY et al. JCI Insight 2020; 5 (12) LC-FACSeq is a method for detecting rare clones in leukemia.
Abu-Shahba AG et al. Tissue Eng Regen Med 2020; 17 (4):477-493 Proangiogenic Hypoxia-Mimicking Agents Attenuate Osteogenic Potential of Adipose Stem/Stromal Cells.
Li M et al. Nat Commun 2020; 11 (1):4051 Clearance of HIV infection by selective elimination of host cells capable of producing HIV.
Colomb F et al. Cell Rep 2020; 32 (5):107991 Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy.
Velasco-Hernandez T et al. J Immunother Cancer 2020; 8 (2) Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope.
Ye C et al. FASEB J 2020; A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome.
Kr?ger R et al. Front Immunol 2020; 11:1593 CD70 Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman.
Stoszko M et al. Sci Adv 2020; 6 (33):eaba6617 Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency.
B?zie S et al. Front Immunol 2020; 11:1496 IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection.
Cytlak U et al. Immunity 2020; 53 (2):353-370.e8 Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans.
Richards KA et al. NPJ Vaccines 2020; 5:77 Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans.
Giron LB et al. EBioMedicine 2020; 59:102945 Interferon-α alters host glycosylation machinery during treated HIV infection.
Pierini S et al. JCI Insight 2020; 5 (16) Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
Diedrich T et al. PLoS One 2020; 15 (3):e0230307 Characterization of the immune cell landscape of patients with NAFLD.
Wierzbinska JA et al. Genome Med 2020; 12 (1):29 Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.
Stebegg M et al. Elife 2020; 9 Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination.
Schorer M et al. Nat Commun 2020; 11 (1):1522 Rapid expansion of Treg cells protects from collateral colitis following a viral trigger.
Villazala-Merino S et al. J Allergy Clin Immunol 2020; 145 (3):958-967.e5 Allergen-specific IgE levels and the ability of IgE-allergen complexes to cross-link determine the extent of CD23-mediated T-cell activation.
Easterhoff D et al. JCI Insight 2020; 5 (2) HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
Ryu S et al. Arthritis Res Ther 2020; 22 (1):63 Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis.
Deal C et al. Front Immunol 2020; 11:415 Intact B-Cell Signaling and Function With Host B-Cells 47 Years After Transplantation for X-SCID.
Harris LD et al. Front Cell Infect Microbiol 2020; 10:120 Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions.
Gan H et al. Sci Adv 2020; 6 (14):eaay2793 B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response.
Okumura G et al. J Exp Med 2020; 217 (4) Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells.
Seng A et al. Blood Adv 2020; 4 (7):1325-1339 Coexpression of FOXP3 and a Helios isoform enhances the effectiveness of human engineered regulatory T cells.
H?usler D et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (3) Glatiramer acetate immune modulates B-cell antigen presentation in treatment of MS.
Tufa DM et al. Sci Rep 2020; 10 (1):6335 Prolactin Acts on Myeloid Progenitors to Modulate SMAD7 Expression and Enhance Hematopoietic Stem Cell Differentiation into the NK Cell Lineage.
Rosser EC et al. Cell Metab 2020; 31 (4):837-851.e10 Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells.
Marsh-Wakefield F et al. Clin Transl Immunology 2020; 9 (5):e01133 IgG3 + B cells are associated with the development of multiple sclerosis.
Pollara J et al. Front Immunol 2020; 11:713 Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART? Molecules.
Haschka D et al. Front Immunol 2020; 11:594 Expansion of Neutrophils and Classical and Nonclassical Monocytes as a Hallmark in Relapsing-Remitting Multiple Sclerosis.
Fox A et al. Sci Rep 2020; 10 (1):7651 Cyto-Feature Engineering: A Pipeline for Flow Cytometry Analysis to Uncover Immune Populations and Associations with Disease.
Hanna SJ et al. Diabetologia 2020; 63 (6):1174-1185 Slow progressors to type 1 diabetes lose islet autoantibodies over time, have few islet antigen-specific CD8+ T cells and exhibit a distinct CD95hi B cell phenotype.
Reyes M et al. Nat Med 2020; 26 (3):333-340 An immune-cell signature of bacterial sepsis.
Crawford LB et al. Microorganisms 2020; 8 (4) Human Cytomegalovirus Infection Suppresses CD34+ Progenitor Cell Engraftment in Humanized Mice.
Schulz-Kuhnt A et al. Front Immunol 2020; 11:691 ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure.
Salio M et al. Proc Natl Acad Sci U S A 2020; 117 (19):10465-10475 Ligand-dependent downregulation of MR1 cell surface expression.
Goodwin M et al. Sci Adv 2020; 6 (19):eaaz0571 CRISPR-based gene editing enables FOXP3 gene repair in IPEX patient cells.
Esaulova E et al. Neurol Neuroimmunol Neuroinflamm 2020; 7 (4) Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation.
Szentkereszty M et al. Pathol Oncol Res 2020; 26 (2):1117-1128 Effect of COPD on Inflammation, Lymphoid Functions and Progression-Free Survival during First-Line Chemotherapy in Advanced Non-small Cell Lung Cancer.
Mola S et al. PLoS One 2020; 15 (5):e0233543 A transcriptome-based approach to identify functional modules within and across primary human immune cells.
Jung J et al. Clin Transl Immunology 2020; 9 (6):e1140 Synovial fluid CD69+CD8+ T cells with tissue-resident phenotype mediate perforin-dependent citrullination in rheumatoid arthritis.
Durant L et al. Microbiome 2020; 8 (1):88 Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease.
Ahl PJ et al. Commun Biol 2020; 3 (1):305 Met-Flow, a strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations.
Loughland JR et al. Clin Transl Immunology 2020; 9 (6):e1144 Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection.
Lindesmith LC et al. Cell Mol Gastroenterol Hepatol 2020; 10 (2):245-267 Virus-Host Interactions Between Nonsecretors and Human Norovirus.
Cheng L et al. JCI Insight 2020; 5 (11) Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-Seq.
Aguilar-Brise?o JA et al. Nat Commun 2020; 11 (1):3177 TLR2 on blood monocytes senses dengue virus infection and its expression correlates with disease pathogenesis.
Mencarelli A et al. J Leukoc Biol 2020; 107 (5):797-807 A humanized mouse model to study mast cells mediated cutaneous adverse drug reactions.
Martin-Fernandez M et al. Cell Rep 2020; 31 (6):107633 Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions.
Arcangeli S et al. Front Immunol 2020; 11:1217 Next-Generation Manufacturing Protocols Enriching TSCM CAR T Cells Can Overcome Disease-Specific T Cell Defects in Cancer Patients.
Verstappen GM et al. J Autoimmun 2020; 109:102439 Gene expression profiling of epithelium-associated FcRL4+ B cells in primary Sj?gren's syndrome reveals a pathogenic signature.
Tanimura K et al. ERJ Open Res 2020; 6 (2) Low serum free light chain is associated with risk of COPD exacerbation.
Bowyer G et al. J Exp Med 2020; 217 (7) Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells.
Kim J et al. Arthritis Res Ther 2020; 22 (1):173 Clinical and histological significance of urinary CD11c+ macrophages in lupus nephritis.
Ratajczak MZ et al. Stem Cell Rev Rep 2020; SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45- Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein Activates the Nlrp3 Inflammasome.
Greenshields-Watson A et al. Cell Rep 2020; 32 (2):107885 CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Saxena S et al. Sci Rep 2020; 10 (1):12405 Identification of TNFAIP3 as relapse biomarker and potential therapeutic target for MOG antibody associated diseases.
Abraham J et al. Front Immunol 2020; 11:1430 Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner.
Badura R et al. Front Cell Infect Microbiol 2020; 10:347 Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment.
Schulte-Schrepping J et al. Cell 2020; Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.
Masterman KA et al. J Immunother Cancer 2020; 8 (2) Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate na?ve and memory NY-ESO-1-specific CD8+ T cells.
Johnson BZ et al. Front Immunol 2020; 11:1481 Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response.
Rivera-Correa J et al. PLoS Negl Trop Dis 2020; 14 (7):e0008466 Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections.
Reginia A et al. Brain Sci 2020; 10 (7) Markers of Regenerative Processes in Patients with Bipolar Disorder: A Case-control Study.
Kholodnyuk I et al. J Clin Med 2020; 9 (7) Chemokine Receptors CCR1 and CCR2 on Peripheral Blood Mononuclear Cells of Newly Diagnosed Patients with the CD38-Positive Chronic Lymphocytic Leukemia.
Sztein MB et al. Sci Rep 2020; 10 (1):13581 Salmonella enterica serovar Typhi exposure elicits ex vivo cell-type-specific epigenetic changes in human gut cells.
Kreye J et al. bioRxiv 2020; A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model.
Rai R et al. Nat Commun 2020; 11 (1):4034 Targeted gene correction of human hematopoietic stem cells for the treatment of Wiskott -?Aldrich Syndrome.
Wege AK et al. J Transl Med 2020; 18 (1):316 A novel rabbit derived anti-HER2 antibody with pronounced therapeutic effectiveness on HER2-positive breast cancer cells in vitro and in humanized tumor mice (HTM).
Meikle CK et al. PLoS One 2020; 15 (8):e0236966 Platelet-T cell aggregates in lung cancer patients: Implications for thrombosis.
Benjelloun F et al. Front Immunol 2020; 11:1655 Activation of Toll-Like Receptors Differentially Modulates Inflammation in the Human Reproductive Tract: Preliminary Findings.
Bourdely P et al. Immunity 2020; 53 (2):335-352.e8 Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells.
Salzer B et al. Nat Commun 2020; 11 (1):4166 Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function.
Imura Y et al. JCI Insight 2020; 5 (14) CD19-targeted CAR regulatory T cells suppress B cell pathology without GvHD.
Zhao NQ et al. PLoS One 2020; 15 (9):e0238347 Natural killer cell phenotype is altered in HIV-exposed seronegative women.
Guo N et al. Cell Mol Immunol 2019; 16 (6):568-579 A critical epitope in CD147 facilitates memory CD4+ T-cell hyper-activation in rheumatoid arthritis.
Perugino CA et al. J Allergy Clin Immunol 2019; 143 (2):736-745.e6 Identification of galectin-3 as an autoantigen in patients with IgG4-related disease.
Ratliff ML et al. J Autoimmun 2019; 96:158-167 ARID3a gene profiles are strongly associated with human interferon alpha production.
Loughland JR et al. J Infect Dis 2019; 219 (4):660-671 Plasmodium falciparum Activates CD16+ Dendritic Cells to Produce Tumor Necrosis Factor and Interleukin-10 in Subpatent Malaria.
Booth JS et al. Int Immunol 2019; 31 (2):101-116 Effect of the live oral attenuated typhoid vaccine, Ty21a, on systemic and terminal ileum mucosal CD4+ T memory responses in humans.
Rozmus J et al. Biol Blood Marrow Transplant 2019; 25 (3):451-458 Comprehensive B Cell Phenotyping Profile for Chronic Graft-versus-Host Disease Diagnosis.
Rataj F et al. Br J Cancer 2019; 120 (1):79-87 High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy.
Wiedemann GM et al. Transl Oncol 2019; 12 (2):350-360 Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma.
Fu J et al. Cell Stem Cell 2019; 24 (2):227-239.e8 Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool.
Senda T et al. Mucosal Immunol 2019; 12 (2):378-389 Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life.
Schlenner S et al. Ann Rheum Dis 2019; 78 (3):342-349 NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology.
Tan C et al. J Biol Chem 2019; 294 (7):2470-2485 A serine in the first transmembrane domain of the human E3 ubiquitin ligase MARCH9 is critical for down-regulation of its protein substrates.
Tong Y et al. MAbs 2019; 11 (2):401-410 De novo generation of specific human IgGs by in vitro immunization using autologous proteins containing immunogenic p-nitrophenylalanine.
Higdon LE et al. J Immunol Methods 2019; 466:17-23 Optimization of single-cell plate sorting for high throughput sequencing applications.
Ha D et al. Proc Natl Acad Sci U S A 2019; 116 (2):609-618 Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody.
Lundqvist S et al. Immunology 2019; 156 (3):259-269 Frequency and immunophenotype of IL10-producing regulatory B cells in optic neuritis.
Kuranda K et al. Mol Ther Methods Clin Dev 2019; 13:112-120 In?Vitro Expansion of Anti-viral T Cells from Cord Blood by Accelerated Co-cultured Dendritic Cells.
Nayak RC et al. Nat Commun 2019; 10 (1):46 The signaling axis atypical protein kinase C λ/ι-Satb2 mediates leukemic transformation of B-cell progenitors.
Koppejan H et al. Arthritis Res Ther 2019; 21 (1):3 Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis.
Lechner A et al. Oncoimmunology 2019; 8 (3):1535293 Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma.
Blijdorp ICJ et al. Arthritis Rheumatol 2019; 71 (3):392-402 Expansion of Interleukin-22- and Granulocyte-Macrophage Colony-Stimulating Factor-Expressing, but Not Interleukin-17A-Expressing, Group 3 Innate Lymphoid Cells in the Inflamed Joints of Patients With Spondyloarthritis.
Zhang X et al. JCI Insight 2019; 4 (2) A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity.
Gorman JA et al. Front Immunol 2019; 10:44 The TYK2-P1104A Autoimmune Protective Variant Limits Coordinate Signals Required to Generate Specialized T Cell Subsets.
Luo Z et al. AIDS 2019; 33 (1):33-44 Increased influenza-specific antibody avidity in HIV-infected women compared with HIV-infected men on antiretroviral therapy.
Shannon I et al. Sci Rep 2019; 9 (1):791 Differences in the influenza-specific CD4 T cell immunodominance hierarchy and functional potential between children and young adults.
Schmidl C et al. Nat Chem Biol 2019; 15 (3):232-240 Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL.
Sol?-Riera C et al. Sci Rep 2019; 9 (1):834 Orthohantaviruses belonging to three phylogroups all inhibit apoptosis in infected target cells.
Kriegsmann K et al. Blood Cancer J 2019; 9 (2):13 Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients.
Goodridge JP et al. Nat Commun 2019; 10 (1):514 Remodeling of secretory lysosomes during education tunes functional potential in NK cells.
Arrey F et al. Front Immunol 2019; 10:89 Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens.
Freitas GRR et al. Aging Dis 2019; 10 (1):49-61 Aging and End Stage Renal Disease Cause A Decrease in Absolute Circulating Lymphocyte Counts with A Shift to A Memory Profile and Diverge in Treg Population.
Kaur M et al. J Immunol 2019; 202 (6):1885-1894 Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice.
Cypris O et al. Clin Epigenetics 2019; 11 (1):19 Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells.
Faliti CE et al. J Exp Med 2019; 216 (2):317-336 P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus.
Franco LM et al. J Exp Med 2019; 216 (2):384-406 Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses.
Li Y et al. Front Immunol 2019; 10:63 Humanized Mice Reveal New Insights Into the Thymic Selection of Human Autoreactive CD8+ T Cells.
Bouafia A et al. J Clin Invest 2019; 129 (3):1047-1060 Loss of ARHGEF1 causes a human primary antibody deficiency.
Wen Z et al. Nat Immunol 2019; 20 (3):313-325 N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation.
Anzilotti C et al. Nat Immunol 2019; 20 (3):350-361 An essential role for the Zn2+ transporter ZIP7 in B cell development.
Smith MJ et al. JCI Insight 2019; 4 (3) Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity.
Gonnord P et al. Oncoimmunology 2019; 8 (4):e1570774 Multiparametric analysis of CD8+ T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy.
Papachristofilou A et al. J Immunother Cancer 2019; 7 (1):38 Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer.
G?rtner K et al. J Extracell Vesicles 2019; 8 (1):1573051 Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL.
R?destad E et al. Front Immunol 2019; 10:189 Individualization of Hematopoietic Stem Cell Transplantation Using Alpha/Beta T-Cell Depletion.
Shah NJ et al. Nat Biotechnol 2019; 37 (3):293-302 An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation.
Du H et al. Cancer Cell 2019; 35 (2):221-237.e8 Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells.
Lepzien R et al. J Leukoc Biol 2019; 105 (4):797-807 Mapping mononuclear phagocytes in blood, lungs, and lymph nodes of sarcoidosis patients.
Zhang L et al. Mol Pain 2019; 15:1744806919828921 ERK and p38 contribute to the regulation of nociceptin and the nociceptin receptor in human peripheral blood leukocytes.
Eken A et al. Front Immunol 2019; 10:217 Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells.
Luo Z et al. Microbiome 2019; 7 (1):25 Systemic translocation of Staphylococcus drives autoantibody production in HIV disease.
Murray D et al. Blood Adv 2019; 3 (4):519-530 Progression of mycosis fungoides occurs through divergence of tumor immunophenotype by differential expression of HLA-DR.
Tardif V et al. Nat Commun 2019; 10 (1):823 Adenosine deaminase-1 delineates human follicular helper T cell function and is altered with HIV.
Furie R et al. J Clin Invest 2019; 129 (3):1359-1371 Monoclonal antibody targeting BDCA2 ameliorates skin lesions in systemic lupus erythematosus.
Schulthess J et al. Immunity 2019; 50 (2):432-445.e7 The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.
Walk J et al. Nat Commun 2019; 10 (1):874 Outcomes of controlled human malaria infection after BCG vaccination.
G?mez-Ch?vez F et al. Front Immunol 2019; 10:285 Maternal Immune Response During Pregnancy and Vertical Transmission in Human Toxoplasmosis.
Huijbers MG et al. Neurol Neuroimmunol Neuroinflamm 2019; 6 (3):e547 MuSK myasthenia gravis monoclonal antibodies: Valency dictates pathogenicity.
Wiedemann A et al. PLoS One 2019; 14 (2):e0212525 B cell subset distribution in human bone marrow is stable and similar in left and right femur: An instructive case.
Kumar P et al. Blood Adv 2019; 3 (4):681-691 HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells.
Semple KM et al. Clin Transl Sci 2019; 12 (3):283-290 Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD20-Specific Cytotoxicity Induced by?Ofatumumab.
Sagebiel AF et al. Nat Commun 2019; 10 (1):975 Tissue-resident Eomes+ NK cells are the major innate lymphoid cell population in human infant intestine.
Foote JR et al. Front Immunol 2019; 10:188 Variations in the Phagosomal Environment of Human Neutrophils and Mononuclear Phagocyte Subsets.
Latour S et al. Cancers (Basel) 2019; 11 (3) Role of Calcium Signaling in GA101-Induced Cell Death in Malignant Human B Cells.
Tripathi T et al. Immunohorizons 2019; 3 (3):110-120 Central Roles of OX40L-OX40 Interaction in the Induction and Progression of Human T Cell-Driven Acute Graft-versus-Host Disease.
Wang K et al. Cell Rep 2019; 26 (10):2580-2592.e7 Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells.
Lu E et al. Nature 2019; 567 (7747):244-248 S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8.
Hussain K et al. Front Immunol 2019; 10:390 Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.
Nivarthi UK et al. EBioMedicine 2019; 41:465-478 Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection model.
Perdomo-Celis F et al. Pathogens 2019; 8 (1) HIV Replication in Humanized IL-3/GM-CSF-Transgenic NOG Mice.
Krebs SJ et al. Immunity 2019; 50 (3):677-691.e13 Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.
Galloway SAE et al. Front Immunol 2019; 10:319 Peptide Super-Agonist Enhances T-Cell Responses to Melanoma.
Maidji E et al. Viruses 2019; 11 (3) Cellular HIV Reservoirs and Viral Rebound from the Lymphoid Compartments of 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine (EFdA)-Suppressed Humanized Mice.
Ferreira CC et al. Arthritis Res Ther 2019; 21 (1):75 Impact of synthetic and biological immunomodulatory therapy on the duration of 17DD yellow fever vaccine-induced immunity in rheumatoid arthritis.
Booth JS et al. Front Immunol 2019; 10:424 Attenuated Oral Typhoid Vaccine Ty21a Elicits Lamina Propria and Intra-Epithelial Lymphocyte Tissue-Resident Effector Memory CD8 T Responses in the Human Terminal Ileum.
Jones D et al. PLoS Pathog 2019; 15 (3):e1007650 Varicella zoster virus productively infects human peripheral blood mononuclear cells to modulate expression of immunoinhibitory proteins and blocking PD-L1 enhances virus-specific CD8+ T cell effector function.
Mennan C et al. Stem Cell Res Ther 2019; 10 (1):99 A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells.
Russo MA et al. J Neuroinflammation 2019; 16 (1):63 Expansion and activation of distinct central memory T lymphocyte subsets in complex regional pain syndrome.
Oda H et al. Front Immunol 2019; 10:479 Second Case of HOIP Deficiency Expands Clinical Features and Defines Inflammatory Transcriptome Regulated by LUBAC.
Tomi? S et al. Front Immunol 2019; 10:475 Prostaglanin-E2 Potentiates the Suppressive Functions of Human Mononuclear Myeloid-Derived Suppressor Cells and Increases Their Capacity to Expand IL-10-Producing Regulatory T Cell Subsets.
Wanjalla CN et al. Front Immunol 2019; 10:408 Adipose Tissue in Persons With HIV Is Enriched for CD4+ T Effector Memory and T Effector Memory RA+ Cells, Which Show Higher CD69 Expression and CD57, CX3CR1, GPR56 Co-expression With Increasing Glucose Intolerance.
Felices M et al. Blood Adv 2019; 3 (6):897-907 Novel CD19-targeted TriKE restores NK cell function and proliferative capacity in CLL.
Hudspeth K et al. Clin Exp Immunol 2019; 196 (2):226-236 Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus.
Barba T et al. Front Immunol 2019; 10:513 Highly Variable Sialylation Status of Donor-Specific Antibodies Does Not Impact Humoral Rejection Outcomes.
Tufa DM et al. Front Immunol 2019; 10:510 Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation.
Karahan GE et al. Transplantation 2019; 103 (4):716-723 An Easy and Sensitive Method to Profile the Antibody Specificities of HLA-specific Memory B Cells.
Mannerstr?m B et al. Epigenetics 2019; 14 (4):352-364 Epigenetic alterations in mesenchymal stem cells by osteosarcoma-derived extracellular vesicles.
Do P et al. J Immunol 2019; 202 (9):2806-2816 Leukemic B Cell CTLA-4 Suppresses Costimulation of T Cells.
Rapp M et al. J Exp Med 2019; 216 (5):1170-1181 CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes.
von Essen MR et al. Cells 2019; 8 (3) IL-6, IL-12, and IL-23 STAT-Pathway Genetic Risk and Responsiveness of Lymphocytes in Patients with Multiple Sclerosis.
Jeong JH et al. Immune Netw 2019; 19 (3):e21 Prominent Inflammatory Features of Monocytes/Macrophages in Acute Calcium Pyrophosphate Crystal Arthritis: a Comparison with Acute Gouty Arthritis.
Hua P et al. Sci Rep 2019; 9 (1):5300 Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion.
Yap HY et al. Adv Virol 2019; 2019:6464521 Epstein-Barr Virus- (EBV-) Immortalized Lymphoblastoid Cell Lines (LCLs) Express High Level of CD23 but Low CD27 to Support Their Growth.
Cron MA et al. Front Immunol 2019; 10:539 Causes and Consequences of miR-150-5p Dysregulation in Myasthenia Gravis.
H?rd J et al. Genome Biol 2019; 20 (1):68 Conbase: a software for unsupervised discovery of clonal somatic mutations in single cells through read phasing.
Belizaire R et al. Blood Adv 2019; 3 (7):969-979 Efficacy and immunologic effects of extracorporeal photopheresis plus interleukin-2 in chronic graft-versus-host disease.
Guimar?es FTL et al. Front Pediatr 2019; 7:114 Pediatric Patients With Steroid-Sensitive Nephrotic Syndrome Have Higher Expression of T Regulatory Lymphocytes in Comparison to Steroid-Resistant Disease.
Booth JS et al. Hum Vaccin Immunother 2019; 15 (6):1409-1420 Association between S. Typhi-specific memory CD4+ and CD8+ T responses in the terminal ileum mucosa and in peripheral blood elicited by the live oral typhoid vaccine Ty21a in humans.
Zhou L et al. Nature 2019; 568 (7752):405-409 Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2.
Nienen M et al. Front Immunol 2019; 10:593 The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains.
Schiroli G et al. Cell Stem Cell 2019; 24 (4):551-565.e8 Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response.
Zimmerman KA et al. J Am Soc Nephrol 2019; 30 (5):767-781 Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species.
Easterbrook J et al. Stem Cell Reports 2019; 12 (5):1056-1068 Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo.
Pavel-Dinu M et al. Nat Commun 2019; 10 (1):1634 Gene correction for SCID-X1 in long-term hematopoietic stem cells.
Planchais C et al. Cell Rep 2019; 27 (2):572-585.e7 HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells.
Ye Y et al. Arthritis Res Ther 2019; 21 (1):92 Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis.
K?ksal H et al. Blood Adv 2019; 3 (8):1230-1243 Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma.
Wang H et al. Theranostics 2019; 9 (8):2315-2324 Human LAP+GARP+FOXP3+ regulatory T cells attenuate xenogeneic graft versus host disease.
Cassetta L et al. Cancer Cell 2019; 35 (4):588-602.e10 Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Zimmermann M et al. Front Immunol 2019; 10:829 Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells.
Medina BD et al. J Exp Med 2019; 216 (6):1359-1376 Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity.
Adhikary SR et al. Purinergic Signal 2019; 15 (2):177-192 Altered donor P2X7 activity in human leukocytes correlates with P2RX7 genotype but does not affect the development of graft-versus-host disease in humanised mice.
Ferdosi SR et al. Nat Commun 2019; 10 (1):1842 Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes.
Forlani G et al. Front Microbiol 2019; 10:819 HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients.
Jiang DM et al. Oncotarget 2019; 10 (31):2947-2958 Phase I study of local radiation and tremelimumab in patients with inoperable locally recurrent or metastatic breast cancer.
Terahara K et al. BMC Res Notes 2019; 12 (1):242 A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro.
Saucourt C et al. Stem Cells Transl Med 2019; 8 (8):822-832 Design and Validation of an Automated Process for the Expansion of Peripheral Blood-Derived CD34+ Cells for Clinical Use After Myocardial Infarction.
Staniek J et al. Front Immunol 2019; 10:951 TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.
Fernandez IZ et al. J Exp Med 2019; 216 (6):1255-1267 A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.
Zhang Z et al. J Exp Med 2019; 216 (6):1311-1327 Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance.
Lossos C et al. Cancer Discov 2019; 9 (7):944-961 Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents.
Karimzadeh H et al. Gastroenterology 2019; 156 (6):1820-1833 Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8+ T Cells and Evolve at the Population Level.
Xia Y et al. Gastroenterol Res Pract 2019; 2019:5436961 Optimizing the Method of Cell Separation from Bile of Patients with Cholangiocarcinoma for Flow Cytometry.
Suurmond J et al. JCI Insight 2019; 4 (9) Patterns of ANA+ B cells for SLE patient stratification.
Ghofrani J et al. Eur J Immunol 2019; 49 (8):1153-1166 Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells.
Zhang F et al. Nat Immunol 2019; 20 (7):928-942 Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.
Zhang W et al. Front Microbiol 2019; 10:977 Probiotic Lactobacillus rhamnosus GG Induces Alterations in Ileal Microbiota With Associated CD3-CD19-T-bet+IFNγ+/- Cell Subset Homeostasis in Pigs Challenged With Salmonella enterica Serovar 4,[5],12:i:.
Durand M et al. J Exp Med 2019; 216 (7):1561-1581 Human lymphoid organ cDC2 and macrophages play complementary roles in T follicular helper responses.
Lo TH et al. PLoS One 2019; 14 (5):e0216368 Examination of CD302 as a potential therapeutic target for acute myeloid leukemia.
Dieudonn? Y et al. J Autoimmun 2019; 102:150-158 Transitional B cells in quiescent SLE: An early checkpoint imprinted by IFN.
Lindestam Arlehamn CS et al. J Immunol 2019; 203 (1):84-92 Widespread Tau-Specific CD4 T Cell Reactivity in the General Population.
Adelman ER et al. Cancer Discov 2019; 9 (8):1080-1101 Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia.
Umeshappa CS et al. Nat Commun 2019; 10 (1):2150 Suppression of a broad spectrum of liver autoimmune pathologies by single peptide-MHC-based nanomedicines.
Golebski K et al. Nat Commun 2019; 10 (1):2162 IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation.
Kim ST et al. J Immunother Cancer 2019; 7 (1):126 Recurrent pseudogout after therapy with immune checkpoint inhibitors: a case report with immunoprofiling of synovial fluid at each flare.
Deng J et al. Cancer Immunol Res 2019; 7 (7):1079-1090 Hypoxia-Induced VISTA Promotes the Suppressive Function of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment.
Shea LK et al. Blood Cancer J 2019; 9 (6):47 Fc receptor-like 2 (FCRL2) is a novel marker of low-risk CLL and refines prognostication based on IGHV mutation status.
Juno JA et al. J Virol 2019; 93 (11) Modulation of the CCR5 Receptor/Ligand Axis by Seminal Plasma and the Utility of In Vitro versus In Vivo Models.
Zumaquero E et al. Elife 2019; 8 IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation.
Garcia-Perez JE et al. Front Immunol 2019; 10:998 CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade.
Watanabe A et al. JCI Insight 2019; 4 (10) Self-tolerance curtails the B cell repertoire to microbial epitopes.
Beaussant-Cohen S et al. J Allergy Clin Immunol 2019; 144 (2):606-608.e4 Combined immunodeficiency in a patient with c-Rel deficiency.
Watanabe A et al. Cell 2019; 177 (5):1124-1135.e16 Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism.
Scharenberg M et al. Front Immunol 2019; 10:1116 Influenza A Virus Infection Induces Hyperresponsiveness in Human Lung Tissue-Resident and Peripheral Blood NK Cells.
Gadalla R et al. Front Oncol 2019; 9:415 Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials.
Perrier-Groult E et al. PLoS One 2019; 14 (5):e0217183 Evaluation of the biocompatibility and stability of allogeneic tissue-engineered cartilage in humanized mice.
Jimenez Vera E et al. PLoS One 2019; 14 (5):e0217163 Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients.
Ritter M et al. PLoS Negl Trop Dis 2019; 13 (5):e0007436 Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment.
Finotello F et al. Genome Med 2019; 11 (1):34 Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data.
Lee EJ et al. Int J Mol Sci 2019; 20 (10) Immunoglobulin Binding Protein 1 as a Potential Urine Biomarker in Patients with Lupus Nephritis.
Fine N et al. Blood Adv 2019; 3 (10):1622-1637 Primed PMNs in healthy mouse and human circulation are first responders during acute inflammation.
Sebode M et al. Front Immunol 2019; 10:1065 Inflammatory Phenotype of Intrahepatic Sulfatide-Reactive Type II NKT Cells in Humans With Autoimmune Hepatitis.
Chatterjee B et al. PLoS Pathog 2019; 15 (5):e1007748 CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo.
Nienhaus F et al. Molecules 2019; 24 (11) Phagocytosis of a PFOB-Nanoemulsion for 19F Magnetic Resonance Imaging: First Results in Monocytes of Patients with Stable Coronary Artery Disease and ST-Elevation Myocardial Infarction.
Park SH et al. Nucleic Acids Res 2019; 47 (15):7955-7972 Highly efficient editing of the?β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease.
Agraz-Doblas A et al. Haematologica 2019; 104 (6):1176-1188 Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis.
Salomonsson M et al. Clin Exp Allergy 2019; 49 (6):874-882 Circulating mast cell progenitors correlate with reduced lung function in allergic asthma.
Oko LM et al. PLoS Pathog 2019; 15 (6):e1007849 Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression.
Ardain A et al. Nature 2019; 570 (7762):528-532 Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Hill DL et al. J Exp Med 2019; 216 (8):1857-1873 The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes.
Celis-Gutierrez J et al. Cell Rep 2019; 27 (11):3315-3330.e7 Quantitative Interactomics in Primary T Cells Provides a Rationale for Concomitant PD-1 and BTLA Coinhibitor Blockade in Cancer Immunotherapy.
Xiao S et al. Stem Cells Int 2019; 2019:9158016 IL-10 Gene-Modified Human Amniotic Mesenchymal Stem Cells Augment Regenerative Wound Healing by Multiple Synergistic Effects.
Palomares Cabeza V et al. Front Bioeng Biotechnol 2019; 7:142 Pediatric Mesenchymal Stem Cells Exhibit Immunomodulatory Properties Toward Allogeneic T and B Cells Under Inflammatory Conditions.
Grau-Vorster M et al. Stem Cell Res Ther 2019; 10 (1):164 HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site study.
Pollmann R et al. Front Immunol 2019; 10:1375 Identification of Autoreactive B Cell Subpopulations in Peripheral Blood of Autoimmune Patients With Pemphigus Vulgaris.
Haas JT et al. Nat Metab 2019; 1 (6):604-614 Transcriptional Network Analysis Implicates Altered Hepatic Immune Function in NASH development and resolution.
Ca?ete PF et al. J Exp Med 2019; 216 (8):1843-1856 Regulatory roles of IL-10-producing human follicular T cells.
Arazi A et al. Nat Immunol 2019; 20 (7):902-914 The immune cell landscape in kidneys of patients with lupus nephritis.
Schoofs T et al. Immunity 2019; 50 (6):1513-1529.e9 Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
van Langelaar J et al. Ann Neurol 2019; 86 (2):264-278 Induction of brain-infiltrating T-bet-expressing B cells in multiple sclerosis.
Lopes AP et al. Front Immunol 2019; 10:1335 MicroRNA-130a Contributes to Type-2 Classical DC-activation in Sj?gren's Syndrome by Targeting Mitogen- and Stress-Activated Protein Kinase-1.
Jiang M et al. Mediators Inflamm 2019; 2019:3140183 ILC2s Induce Adaptive Th2-Type Immunity in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
Liechti T et al. J Exp Med 2019; 216 (9):2071-2090 Widespread B cell perturbations in HIV-1 infection afflict naive and marginal zone B cells.
da Costa-Rocha IA et al. Front Immunol 2019; 10:1211 Duration of Humoral and Cellular Immunity 8 Years After Administration of Reduced Doses of the 17DD-Yellow Fever Vaccine.
Clarke J et al. J Exp Med 2019; 216 (9):2128-2149 Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer.
Chapuis AG et al. Nat Med 2019; 25 (7):1064-1072 T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant.
Ryzhov S et al. J Am Heart Assoc 2019; 8 (13):e010874 Number of Circulating CD 73-Expressing Lymphocytes Correlates With Survival After Cardiac Arrest.
Munteanu AN et al. Exp Ther Med 2019; 18 (3):1693-1700 Peripheral immune cell markers in children with recurrent respiratory infections in the absence of primary immunodeficiency.
Boileau M et al. Nat Commun 2019; 10 (1):2891 Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness.
Ma W et al. BMC Mol Cell Biol 2019; 20 (1):20 Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose.
Wang C et al. EBioMedicine 2019; 45:578-587 Sphingomyelin synthase 1 enhances BCR signaling to promote lupus-like autoimmune response.
Armand P et al. Blood 2019; 134 (1):22-29 PD-1 blockade with pembrolizumab for classical Hodgkin lymphoma after autologous stem cell transplantation.
Choi YH et al. J Immunother Cancer 2019; 7 (1):168 IL-27 enhances IL-15/IL-18-mediated activation of human natural killer cells.
Kurupati RK et al. Aging (Albany NY) 2019; 11 (13):4367-4381 Age-related changes in B cell metabolism.
Inagaki-Katashiba N et al. Eur J Immunol 2019; 49 (11):2051-2062 Statins can suppress DC-mediated Th2 responses through the repression of OX40-ligand and CCL17 expression.
Zhang J et al. Sci Rep 2019; 9 (1):10090 Circulating CXCR3+ Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients.
Kibata K et al. J Blood Med 2019; 10:217-226 The immunomodulatory-drug, lenalidomide, sustains and enhances interferon-α production by human plasmacytoid dendritic cells.
Bonaccorsi I et al. Front Immunol 2019; 10:1503 Symptomatic Carotid Atherosclerotic Plaques Are Associated With Increased Infiltration of Natural Killer (NK) Cells and Higher Serum Levels of NK Activating Receptor Ligands.
Kato R et al. Front Immunol 2019; 10:1619 CD4+CD25+LAG3+ T Cells With a Feature of Th17 Cells Associated With Systemic Lupus Erythematosus Disease Activity.
Serwas NK et al. Nat Commun 2019; 10 (1):3106 Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.
Allden SJ et al. Am J Respir Crit Care Med 2019; 200 (2):209-219 The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis.
Meckiff BJ et al. J Immunol 2019; 203 (5):1276-1287 Primary EBV Infection Induces an Acute Wave of Activated Antigen-Specific Cytotoxic CD4+ T Cells.
Hartmann FJ et al. Cell Rep 2019; 28 (3):819-831.e4 Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy.
Nowak WN et al. Mediators Inflamm 2019; 2019:1868170 Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo.
Kim JW et al. Immune Netw 2019; 19 (4):e26 Circulating CCR7loPD-1hi Follicular Helper T Cells Indicate Disease Activity and Glandular Inflammation in Patients with Primary Sj?gren's Syndrome.
Nerreter T et al. Nat Commun 2019; 10 (1):3137 Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T.
Wang H et al. Nat Commun 2019; 10 (1):3254 Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity.
Banga R et al. PLoS Pathog 2019; 15 (7):e1007918 Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.
Ackermann C et al. Sci Rep 2019; 9 (1):10624 HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules.
Shih T et al. Front Immunol 2019; 10:1652 RNAi Transfection Optimized in Primary Na?ve B Cells for the Targeted Analysis of Human Plasma Cell Differentiation.
Cho A et al. Cell Rep 2019; 28 (4):909-922.e6 Single-Cell Analysis Suggests that Ongoing Affinity Maturation Drives the Emergence of Pemphigus Vulgaris Autoimmune Disease.
Faleiro R et al. Clin Transl Immunology 2019; 8 (7):e01071 Crohn's disease is facilitated by a disturbance of programmed death-1 ligand 2 on blood dendritic cells.
Bancroft T et al. J Exp Med 2019; 216 (10):2331-2347 Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
Solimani F et al. Front Immunol 2019; 10:1808 Therapeutic Targeting of Th17/Tc17 Cells Leads to Clinical Improvement of Lichen Planus.
Campi-Azevedo AC et al. Emerg Infect Dis 2019; 25 (8):1511-1521 17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil.
Becker M et al. Mol Metab 2019; 28:73-82 Short-term cold exposure supports human Treg induction in?vivo.
Leite Pereira A et al. Front Immunol 2019; 10:1777 Characterization of Leukocytes From HIV-ART Patients Using Combined Cytometric Profiles of 72 Cell Markers.
Kildey K et al. Front Immunol 2019; 10:1877 Specialized Roles of Human Natural Killer Cell Subsets in Kidney Transplant Rejection.
Yun JW et al. Cancers (Basel) 2019; 11 (8) A Novel Type of Blood Biomarker: Distinct Changes of Cytokine-Induced STAT Phosphorylation in Blood T Cells Between Colorectal Cancer Patients and Healthy Individuals.
Nevalainen T et al. Immun Ageing 2019; 16:19 CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males.
Br?ker K et al. Front Bioeng Biotechnol 2019; 7:194 Mass Production of Highly Active NK Cells for Cancer Immunotherapy in a GMP Conform Perfusion Bioreactor.
Acquaviva M et al. Front Immunol 2019; 10:1922 Loss of Circulating CD8+ CD161high T Cells in Primary Progressive Multiple Sclerosis.
Yousefi Z et al. Leuk Res Rep 2019; 12:100181 Prognostic significance of Fc receptor-like 1 in patients with chronic lymphocytic leukemia, hairy cell leukemia, and various B-cell non-Hodgkin's lymphoma.
Fox JJ et al. Am J Clin Exp Urol 2019; 7 (4):281-296 Mass cytometry reveals species-specific differences and a new level of complexity for immune cells in the prostate.
Wagstaffe HR et al. J Immunol 2019; 203 (6):1609-1618 Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and NK Cell Function.
Crawford LB et al. mBio 2019; 10 (4) Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34+ Hematopoietic Progenitor Cells and Humanized NSG Mice.
Ormh?j M et al. Clin Cancer Res 2019; 25 (23):7046-7057 Chimeric Antigen Receptor T Cells Targeting CD79b Show Efficacy in Lymphoma with or without Cotargeting CD19.
DeWolfe D et al. Front Immunol 2019; 10:1890 NK Cells Contribute to the Immune Risk Profile in Kidney Transplant Candidates.
Marquardt N et al. Nat Commun 2019; 10 (1):3841 Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.
Conde CD et al. J Clin Invest 2019; 129 (10):4194-4206 Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress.
Rasoulouniriana D et al. J Clin Invest 2019; 129 (10):4151-4164 A distinct subset of FcγRI-expressing Th1 cells exert antibody-mediated cytotoxic activity.
Tauber C et al. Oncotarget 2019; 10 (50):5194-5206 Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma.
Apodaca MC et al. J Immunother Cancer 2019; 7 (1):230 Characterization of a whole blood assay for quantifying myeloid-derived suppressor cells.
Burbano C et al. Front Immunol 2019; 10:2058 Proinflammatory Differentiation of Macrophages Through Microparticles That Form Immune Complexes Leads to T- and B-Cell Activation in Systemic Autoimmune Diseases.
Yang C et al. Nat Commun 2019; 10 (1):3931 Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome.
Soon CF et al. Front Immunol 2019; 10:2076 Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy.
Gomez-Ospina N et al. Nat Commun 2019; 10 (1):4045 Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I.
Matsuyama H et al. Sci Rep 2019; 9 (1):13181 Activation of mucosal-associated invariant T cells in the lungs of sarcoidosis patients.
Enqvist M et al. Front Immunol 2019; 10:2085 Systemic and Intra-Nodal Activation of NK Cells After Rituximab Monotherapy for Follicular Lymphoma.
Hashwah H et al. EMBO Mol Med 2019; 11 (10):e10576 The IL-6 signaling complex is a critical driver, negative prognostic factor, and therapeutic target in diffuse large B-cell lymphoma.
Naluyima P et al. J Immunol 2019; 203 (8):2210-2221 Terminal Effector CD8 T Cells Defined by an IKZF2+IL-7R- Transcriptional Signature Express FcγRIIIA, Expand in HIV Infection, and Mediate Potent HIV-Specific Antibody-Dependent Cellular Cytotoxicity.
Fajgenbaum DC et al. J Clin Invest 2019; 129 (10):4451-4463 Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease.
Banerjee P et al. Cancer Immunol Res 2019; 7 (12):2036-2051 Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia.
Rodriguez R et al. J Exp Med 2019; 216 (12):2800-2818 Concomitant PIK3CD and TNFRSF9 deficiencies cause chronic active Epstein-Barr virus infection of T cells.
Carvelli J et al. Front Immunol 2019; 10:2179 Imbalance of Circulating Innate Lymphoid Cell Subpopulations in Patients With Septic Shock.
Branco ACCC et al. Sci Rep 2019; 9 (1):13721 Proinflammatory profile of neonatal monocytes induced by microbial ligands is downmodulated by histamine.
McLeod B et al. Nat Commun 2019; 10 (1):4328 Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.
Kholodnyuk I et al. Medicina (Kaunas) 2019; 55 (10) Proportion of the CD19-Positive and CD19-Negative Lymphocytes and Monocytes within the Peripheral Blood Mononuclear Cell Set is Characteristic for Rheumatoid Arthritis.
Campi-Azevedo AC et al. Front Immunol 2019; 10:2192 Short-Lived Immunity After 17DD Yellow Fever Single Dose Indicates That Booster Vaccination May Be Required to Guarantee Protective Immunity in Children.
G?tzke H et al. Nat Commun 2019; 10 (1):4403 The ALFA-tag is a highly versatile tool for nanobody-based bioscience applications.
Beltr?n E et al. J Clin Invest 2019; 129 (11):4758-4768 Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis.
Bonne-Ann?e S et al. Sci Rep 2019; 9 (1):14305 Differential Modulation of Human Innate Lymphoid Cell (ILC) Subsets by IL-10 and TGF-β.
Caeser R et al. Nat Commun 2019; 10 (1):4543 Genetic modification of primary human B cells to model high-grade lymphoma.
Crisler WJ et al. Life Sci Alliance 2019; 2 (5) Ligand-induced IFNGR1 down-regulation calibrates myeloid cell IFNγ responsiveness.
Mastelic-Gavillet B et al. J Immunother Cancer 2019; 7 (1):257 Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8+ T cells.
Agarwal S et al. Oncoimmunology 2019; 8 (12):e1671761 In vivo generated human CAR T cells eradicate tumor cells.
Smith C et al. J Clin Invest 2019; 129 (11):5020-5032 T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response.
Winklmeier S et al. Neurol Neuroimmunol Neuroinflamm 2019; 6 (6):625 Identification of circulating MOG-specific B cells in patients with MOG antibodies.
Bruggeman CW et al. PLoS One 2019; 14 (10):e0223264 Tissue-specific expression of IgG receptors by human macrophages ex vivo.
Henry C et al. J Virol 2019; 93 (21) Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study.
Stowe CL et al. Elife 2019; 8 Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin.
Bocharnikov AV et al. JCI Insight 2019; 4 (20) PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
Cantero-P?rez J et al. Nat Commun 2019; 10 (1):4739 Resident memory T cells are a cellular reservoir for HIV in the cervical mucosa.
Wagenblast E et al. Nat Commun 2019; 10 (1):4730 Functional profiling of single CRISPR/Cas9-edited human long-term hematopoietic stem cells.
Meda Spaccamela V et al. Front Immunol 2019; 10:2236 High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease.
Swieboda D et al. Cytometry A 2019; 95 (12):1231-1235 OMIP-062: A 14-Color, 16-Antibody Panel for Immunophenotyping Human Innate Lymphoid, Myeloid and T Cells in Small Volumes of Whole Blood and Pediatric Airway Samples.
Le Gars M et al. Front Immunol 2019; 10:2469 Pregnancy-Induced Alterations in NK Cell Phenotype and Function.
Satta A et al. Front Immunol 2019; 10:2514 A Bispecific Antibody to Link a TRAIL-Based Antitumor Approach to Immunotherapy.
Ladinsky MS et al. Elife 2019; 8 Mechanisms of virus dissemination in bone marrow of HIV-1-infected humanized BLT mice.
Rivera-Mulia JC et al. Blood Adv 2019; 3 (21):3201-3213 Replication timing alterations in leukemia affect clinically relevant chromosome domains.
Mold JE et al. PLoS Biol 2019; 17 (10):e3000383 Cell generation dynamics underlying naive T-cell homeostasis in adult humans.
Burns DM et al. Front Immunol 2019; 10:2489 Non-uniform in vivo Expansion of Epstein-Barr Virus-Specific T-Cells Following Donor Lymphocyte Infusion for Post-transplant Lymphoproliferative Disease.
Giraldo-Villegas M et al. Future Sci OA 2019; 5 (10):FSO423 Polyacrylic acid-coated iron oxide nanoparticles could be a useful tool for tracking inflammatory monocytes.
Upasani V et al. Front Immunol 2019; 10:2500 Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection.
Brown CC et al. Cell 2019; 179 (4):846-863.e24 Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Chen YY et al. JHEP Rep 2019; 1 (5):369-376 Intrahepatic macrophage populations in the pathophysiology of primary sclerosing cholangitis.
Escudero-P?rez B et al. JCI Insight 2019; 4 (21) Comparative pathogenesis of Ebola virus and Reston virus infection in humanized mice.
Shinko D et al. Front Immunol 2019; 10:2584 Mass Cytometry Reveals a Sustained Reduction in CD16+ Natural Killer Cells Following Chemotherapy in Colorectal Cancer Patients.
Fuchs YF et al. Front Immunol 2019; 10:2568 Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level.
Tobin RP et al. Front Oncol 2019; 9:1223 IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients.
Onodera T et al. J Immunol 2019; 203 (12):3282-3292 Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses.
Rivera-Correa J et al. Elife 2019; 8 Atypical memory B-cells are associated with Plasmodium falciparum anemia through anti-phosphatidylserine antibodies.
Waugh KA et al. Cell Rep 2019; 29 (7):1893-1908.e4 Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome.
Hashimoto K et al. Proc Natl Acad Sci U S A 2019; 116 (48):24242-24251 Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.
Auladell M et al. Clin Transl Immunology 2019; 8 (11):e01090 Distinguishing naive- from memory-derived human B cells during acute responses.
Kiani Z et al. J Virol 2019; 93 (23) The Education of NK Cells Determines Their Responsiveness to Autologous HIV-Infected CD4 T Cells.
Pugh J et al. Life Sci Alliance 2019; 2 (6) In vitro education of human natural killer cells by KIR3DL1.
B?zie S et al. Blood Adv 2019; 3 (22):3522-3538 Human CD8+ Tregs expressing a MHC-specific CAR display enhanced suppression of human skin rejection and GVHD in NSG mice.
Carnero Contentti E et al. Front Immunol 2019; 10:2690 Mucosal-Associated Invariant T Cell Features and TCR Repertoire Characteristics During the Course of Multiple Sclerosis.
Sabatino JJ Jr et al. Proc Natl Acad Sci U S A 2019; 116 (51):25800-25807 Anti-CD20 therapy depletes activated myelin-specific CD8+ T cells in multiple sclerosis.
Messias CV et al. BMC Infect Dis 2019; 19 (1):986 Zika virus infects human blood mononuclear cells.
Hazenberg MD et al. Blood Adv 2019; 3 (22):3650-3660 Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease.
Gyurova IE et al. Front Immunol 2019; 10:2728 Dynamic Changes in Natural Killer Cell Subset Frequencies in the Absence of Cytomegalovirus Infection.
Koenig A et al. Nat Commun 2019; 10 (1):5350 Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants.
Polito R et al. Front Immunol 2019; 10:2812 Adiponectin Receptors and Pro-inflammatory Cytokines Are Modulated in Common Variable Immunodeficiency Patients: Correlation With Ig Replacement Therapy.
Batalha IL et al. J Control Release 2019; 314:116-124 Polymeric nanobiotics as a novel treatment for mycobacterial infections.
Wada H et al. Sci Rep 2019; 9 (1):17981 Flow cytometric identification and cell-line establishment of macrophages in naked mole-rats.
Pucino V et al. Cell Metab 2019; 30 (6):1055-1074.e8 Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring.
Heinze A et al. Front Immunol 2019; 10:2816 The Synergistic Use of IL-15 and IL-21 for the Generation of NK Cells From CD3/CD19-Depleted Grafts Improves Their ex vivo Expansion and Cytotoxic Potential Against Neuroblastoma: Perspective for Optimized Immunotherapy Post Haploidentical Stem Cell Transplantation.
M?ller J et al. JCI Insight 2019; 4 (23) Cytomegalovirus infection is a risk factor for tuberculosis disease in infants.
Kim KH et al. Front Immunol 2019; 10:2865 Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C.
Roper SI et al. Elife 2019; 8 B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments.
Herrera L et al. Sci Rep 2019; 9 (1):18729 Adult peripheral blood and umbilical cord blood NK cells are good sources for effective CAR therapy against CD19 positive leukemic cells.
Leylek R et al. Cell Rep 2019; 29 (11):3736-3750.e8 Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population.
Urlaub D et al. Arthritis Res Ther 2019; 21 (1):277 Activation of natural killer cells by rituximab in granulomatosis with polyangiitis.
Jimeno R et al. Elife 2019; 8 Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells.
Vaisman-Mentesh A et al. Front Immunol 2019; 10:2921 Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment With TNFα Antagonists.
Pilon C et al. Front Immunol 2019; 10:2908 Human Apoptotic Cells, Generated by Extracorporeal Photopheresis, Modulate Allogeneic Immune Response.
Lee WI et al. Front Immunol 2019; 10:2833 A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity-Analysis of all Genotypes and Phenotypes.
Hurrell BP et al. Cell Rep 2019; 29 (13):4509-4524.e5 TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity.
Tian Y et al. Cell Rep 2019; 29 (13):4482-4495.e4 Molecular Signatures of Dengue Virus-Specific IL-10/IFN-γ Co-producing CD4?T Cells and Their Association with Dengue Disease.
Jiang L et al. J Immunol Res 2019; 2019:7914326 Efficient Acquisition of Fully Human Antibody Genes against Self-Proteins by Sorting Single B Cells Stimulated with Vaccines Based on Nitrated T Helper Cell Epitopes.
M?ller S et al. Front Immunol 2019; 10:3123 High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia.
Meraz IM et al. Cancer Immunol Res 2019; 7 (8):1267-1279 An Improved Patient-Derived Xenograft Humanized Mouse Model for Evaluation of Lung Cancer Immune Responses.
Cossarizza A et al. Eur J Immunol 2019; 49 (10):1457-1973 Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Kinjyo I et al. J Leukoc Biol 2019; 105 (4):741-753 Leukemia-derived exosomes and cytokines pave the way for entry into the brain.
Nguyen S et al. Sci Transl Med 2019; 11 (523) Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells.
Calvanese V et al. Nature 2019; 576 (7786):281-286 MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment.
Aliprandini E et al. Toxicon X 2019; 2:100006 An oligoclonal combination of human monoclonal antibodies able to neutralize tetanus toxin in vivo.
Satpathy AT et al. Nat Biotechnol 2019; 37 (8):925-936 Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion.
Jordan S et al. Cell 2019; 178 (5):1102-1114.e17 Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool.
Zappasodi R et al. Nat Med 2019; 25 (5):759-766 Rational design of anti-GITR-based combination immunotherapy.
Schulten V et al. J Allergy Clin Immunol 2018; 141 (2):775-777.e6 Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells.
Bogaert DJ et al. J Allergy Clin Immunol 2018; 141 (1):432-435.e7 A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects.
den Hartog G et al. Eur J Immunol 2018; 48 (2):283-292 BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B?cells.
Moore T et al. Cancer Immunol Immunother 2018; 67 (2):311-325 Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.
Jenkins RW et al. Cancer Discov 2018; 8 (2):196-215 Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.
Renand A et al. J Allergy Clin Immunol 2018; 141 (5):1750-1760.e1 Synchronous immune alterations mirror clinical response during allergen immunotherapy.
Wang M et al. FASEB J 2018; 32 (3):1537-1549 Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
Yaguchi T et al. Cell Mol Immunol 2018; 15 (11):953-962 Human PBMC-transferred murine MHC class I/II-deficient NOG mice enable long-term evaluation of human immune responses.
Khamaikawin W et al. Mol Ther Methods Clin Dev 2018; 9:23-32 Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1.
Mayer RL et al. Mol Cell Proteomics 2018; 17 (2):290-303 Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemia.
Tsuda B et al. Breast Cancer 2018; 25 (3):284-291 B-cell populations are expanded in breast cancer patients compared with healthy controls.
Miller JS et al. Clin Cancer Res 2018; 24 (7):1525-1535 A First-in-Human Phase I Study of Subcutaneous Outpatient Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors.
Choi YS et al. Gastroenterology 2018; 154 (4):1047-1060 Tumor Necrosis Factor-producing T-regulatory Cells Are?Associated With Severe Liver Injury in Patients With Acute?Hepatitis A.
Keawvichit R et al. Immunology 2018; 153 (4):455-465 Differences in activation and tissue homing markers of natural killer cell subsets during acute dengue infection.
Amodio D et al. J Immunol 2018; 200 (2):538-550 Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination.
Han SS et al. Oncotarget 2018; 9 (3):3292-3302 BAFF and APRIL expression as an autoimmune signature of membranous nephropathy.
Chambers ES et al. Clin Exp Allergy 2018; 48 (1):13-22 Dendritic cell phenotype in severe asthma reflects clinical responsiveness to glucocorticoids.
Pugh JL et al. J Immunol 2018; 200 (3):1146-1158 Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage.
Hua S et al. Clin Infect Dis 2018; 66 (12):1910-1917 Pegylated Interferon-α-Induced Natural Killer Cell Activation Is Associated With Human Immunodeficiency Virus-1 DNA Decline in Antiretroviral Therapy-Treated HIV-1/Hepatitis C Virus-Coinfected Patients.
Rouha H et al. Virulence 2018; 9 (1):231-247 Disarming Staphylococcus aureus from destroying human cells by simultaneously neutralizing six cytotoxins with two human monoclonal antibodies.
Seang S et al. AIDS Res Hum Retroviruses 2018; 34 (1):39-45 Low Levels of Endothelial Progenitor Cells and Their Association with Systemic Inflammation and Monocyte Activation in Older HIV-Infected Men.
Fan Y et al. Biochem J 2018; 475 (1):23-44 Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.
Cao Q et al. J Am Soc Nephrol 2018; 29 (3):961-976 Potentiating Tissue-Resident Type 2 Innate Lymphoid Cells by IL-33 to Prevent Renal Ischemia-Reperfusion Injury.
Findlay JS et al. Viruses 2018; 10 (1) Blood Coagulation Factor X Exerts Differential Effects on Adenovirus Entry into Human Lymphocytes.
Wang B et al. Nat Biotechnol 2018; 36 (2):152-155 Functional interrogation and mining of natively paired human VH:VL antibody repertoires.
Winter S et al. EMBO Mol Med 2018; 10 (2):188-199 Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility.
Ritter M et al. PLoS Negl Trop Dis 2018; 12 (1):e0006184 Mansonella perstans microfilaremic individuals are characterized by enhanced type 2 helper T and regulatory T and B cell subsets and dampened systemic innate and adaptive immune responses.
Fink C et al. Sci Rep 2018; 8 (1):590 19F-perfluorocarbon-labeled human peripheral blood mononuclear cells can be detected in vivo using clinical MRI parameters in a therapeutic cell setting.
Li H et al. PLoS Genet 2018; 14 (1):e1007163 Identification of an elaborate NK-specific system regulating HLA-C expression.
Ng SS et al. Clin Transl Immunology 2018; 7 (1):e1003 Rapid loss of group 1 innate lymphoid cells during blood stage Plasmodium infection.
McCarthy KR et al. Immunity 2018; 48 (1):174-184.e9 Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires.
Hung CH et al. Sci Rep 2018; 8 (1):919 Altered pattern of monocyte differentiation and monocyte-derived TGF-β1 in severe asthma.
Arruda LCM et al. Blood Adv 2018; 2 (2):126-141 Immune rebound associates with a favorable clinical response to autologous HSCT in systemic sclerosis patients.
Kornilov R et al. J Extracell Vesicles 2018; 7 (1):1422674 Efficient ultrafiltration-based protocol to deplete extracellular vesicles from fetal bovine serum.
Noyan K et al. Front Immunol 2018; 9:19 Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells.
Xu SX et al. PLoS One 2018; 13 (1):e0191672 Neisseria gonorrhoeae co-infection exacerbates vaginal HIV shedding without affecting systemic viral loads in human CD34+ engrafted mice.
Warner WA et al. Blood Adv 2018; 2 (2):151-163 Expression profiling of snoRNAs in normal hematopoiesis and AML.
Kiener R et al. Sci Rep 2018; 8 (1):1474 Vaccine vectors based on Adenovirus 19a/64 exhibit broad cellular tropism and potently restimulate HCMV-specific T cell responses ex vivo.
Messlinger H et al. Front Immunol 2018; 9:24 Monocyte-Derived Signals Activate Human Natural Killer Cells in Response to Leishmania Parasites.
Johnston HE et al. Mol Cell Proteomics 2018; 17 (4):776-791 Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation.
Bak RO et al. Nat Protoc 2018; 13 (2):358-376 CRISPR/Cas9 genome editing in human hematopoietic stem cells.
Guo B et al. Nat Med 2018; 24 (3):360-367 Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis.
Cepeda S et al. Cell Rep 2018; 22 (5):1276-1287 Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens.
Zeng H et al. Sci Adv 2018; 4 (1):eaar5701 Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.
Wong TN et al. Nat Commun 2018; 9 (1):455 Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.
Bujko A et al. J Exp Med 2018; 215 (2):441-458 Transcriptional and functional profiling defines human small intestinal macrophage subsets.
Hulsmans M et al. J Exp Med 2018; 215 (2):423-440 Cardiac macrophages promote diastolic dysfunction.
B?iers C et al. Dev Cell 2018; 44 (3):362-377.e7 A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B?Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Kagoya Y et al. Nat Med 2018; 24 (3):352-359 A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects.
Mamedov MR et al. Immunity 2018; 48 (2):350-363.e7 A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.
Kilinc MO et al. Clin Transl Med 2018; 7 (1):5 The ratio of ADSCs to HSC-progenitors in adipose tissue derived SVF may provide the key to predict the outcome of stem-cell therapy.
Zhou J et al. Theranostics 2018; 8 (6):1575-1590 Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1.
Bill M et al. J Cell Mol Med 2018; 22 (4):2311-2318 Mapping the CLEC12A expression on myeloid progenitors in normal bone marrow; implications for understanding CLEC12A-related cancer stem cell biology.
Doi H et al. J Gastroenterol Hepatol 2018; Enhanced B-cell differentiation driven by advanced cirrhosis resulting in hyperglobulinemia.
Li C et al. Mol Ther Methods Clin Dev 2018; 9:142-152 Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies.
Zhou J et al. Toxicol Sci 2018; 163 (1):319-329 Suppression of the IgM Response by Aryl Hydrocarbon Receptor Activation in Human Primary B Cells Involves Impairment of Immunoglobulin Secretory Processes.
Patas K et al. Front Immunol 2018; 9:291 T Cell Phenotype and T Cell Receptor Repertoire in Patients with Major Depressive Disorder.
Lu N et al. Nat Commun 2018; 9 (1):742 Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4.
Zhang JQ et al. Cancer Immunol Res 2018; 6 (4):434-447 Macrophages and CD8+ T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors.
Blum LK et al. Eur J Immunol 2018; 48 (5):874-884 Circulating plasmablasts are elevated and produce pathogenic anti-endothelial cell autoantibodies in idiopathic pulmonary arterial hypertension.
Anderson J et al. Front Immunol 2018; 9:301 Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans.
Rius C et al. J Immunol 2018; 200 (7):2263-2279 Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations.
Hansen IS et al. Nat Commun 2018; 9 (1):863 FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming.
Oliveira ES et al. Viruses 2018; 10 (3) Increased Levels of Txa? Induced by Dengue Virus Infection in IgM Positive Individuals Is Related to the Mild Symptoms of Dengue.
Wagstaffe HR et al. J Immunol 2018; 200 (8):2738-2747 IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production.
Koreth J et al. Haematologica 2018; 103 (3):522-530 Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results.
Burbano C et al. Front Immunol 2018; 9:322 Potential Involvement of Platelet-Derived Microparticles and Microparticles Forming Immune Complexes during Monocyte Activation in Patients with Systemic Lupus Erythematosus.
Cerignoli F et al. PLoS One 2018; 13 (3):e0193498 In vitro immunotherapy potency assays using real-time cell analysis.
Gomez-Lopez N et al. Am J Reprod Immunol 2018; 79 (4):e12827 The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies.
Berin MC et al. J Allergy Clin Immunol 2018; 142 (1):149-158.e8 Egg-specific IgE and basophil activation but not egg-specific T-cell counts correlate with phenotypes of clinical egg allergy.
Subrahmanyam PB et al. J Immunother Cancer 2018; 6 (1):18 Distinct predictive biomarker candidates for response to anti-CTLA-4 and anti-PD-1 immunotherapy in melanoma patients.
Niu J et al. Clin Exp Immunol 2018; 192 (2):206-212 Dissection of a circulating CD3+ CD20+ T cell subpopulation in patients with psoriasis.
Wetzels S et al. J Vis Exp 2018; (133) Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry.
Gherardin NA et al. Sci Rep 2018; 8 (1):4159 Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma.
Duggal NA et al. Aging Cell 2018; 17 (2) Major features of immunesenescence, including reduced thymic output, are ameliorated by high levels of physical activity in adulthood.
Gies V et al. JCI Insight 2018; 3 (5) Impaired TLR9 responses in B cells from patients with systemic lupus erythematosus.
Vanshylla K et al. Sci Rep 2018; 8 (1):4244 Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells.
Wun KS et al. Nat Immunol 2018; 19 (4):397-406 T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids.
Toapanta FR et al. J Transl Med 2018; 16 (1):61 T cell mediated immunity induced by the live-attenuated Shigella flexneri 2a vaccine candidate CVD 1208S in humans.
Germeshausen M et al. Blood Adv 2018; 2 (6):586-596 MECOM-associated syndrome: a heterogeneous inherited bone marrow failure syndrome with amegakaryocytic thrombocytopenia.
Satheesan S et al. J Virol 2018; 92 (7) HIV Replication and Latency in a Humanized NSG Mouse Model during Suppressive Oral Combinational Antiretroviral Therapy.
Cole C et al. Nucleic Acids Res 2018; 46 (10):e62 Tn5Prime, a Tn5 based 5' capture method for single cell RNA-seq.
Zheng S et al. Mol Syst Biol 2018; 14 (3):e8041 Molecular transitions in early progenitors during human cord blood hematopoiesis.
Ravens S et al. Front Immunol 2018; 9:510 Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy.
Publicover J et al. Sci Transl Med 2018; 10 (433) An OX40/OX40L interaction directs successful immunity to hepatitis B virus.
Motwani MP et al. JCI Insight 2018; 3 (6) Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation.
Otta DA et al. Antimicrob Agents Chemother 2018; 62 (4) Identification of Anti-Trypanosoma cruzi Lead Compounds with Putative Immunomodulatory Activity.
Utzschneider DT et al. Cell Rep 2018; 22 (13):3454-3467 Active Maintenance of T Cell Memory in Acute and Chronic Viral Infection Depends on Continuous Expression of FOXO1.
Garc?a-Salum T et al. Oncotarget 2018; 9 (24):17014-17027 Molecular signatures associated with tumor-specific immune response in melanoma patients treated with dendritic cell-based immunotherapy.
Butler A et al. Nat Biotechnol 2018; 36 (5):411-420 Integrating single-cell transcriptomic data across different conditions, technologies, and species.
Hung CH et al. BMC Cancer 2018; 18 (1):366 Altered monocyte differentiation and macrophage polarization patterns in patients with breast cancer.
Panda SK et al. J Clin Invest 2018; 128 (5):1873-1887 Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.
Chen Q et al. Front Immunol 2018; 9:599 Human Vγ9Vδ2-T Cells Synergize CD4+ T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody.
Asano T et al. Front Immunol 2018; 9:568 Enhanced AKT Phosphorylation of Circulating B Cells in Patients With Activated PI3Kδ Syndrome.
Maehara T et al. Life Sci Alliance 2018; 1 (1) The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo.
Arce Vargas F et al. Cancer Cell 2018; 33 (4):649-663.e4 Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.
Kebir H et al. J Clin Invest 2018; 128 (5):2000-2009 Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis.
Gardner JK et al. PLoS One 2018; 13 (4):e0195313 Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.
Buggert M et al. PLoS Pathog 2018; 14 (4):e1006973 Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease.
He X et al. EMBO J 2018; 37 (11) Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
Surendran N et al. Innate Immun 2018; 24 (4):240-251 TLR agonist combinations that stimulate Th type I polarizing responses from human neonates.
Crawford LB et al. mBio 2018; 9 (2) Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation.
Roders N et al. Front Immunol 2018; 9:787 SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production.
Frascoli M et al. Sci Transl Med 2018; 10 (438) Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α.
Cheung P et al. Cell 2018; 173 (6):1385-1397.e14 Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging.
Heger L et al. Front Immunol 2018; 9:744 CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion.
Lemarquis AL et al. Front Immunol 2018; 9:909 Transitional B Cells and TLR9 Responses Are Defective in Selective IgA Deficiency.
Van Nieuwenhove E et al. J Allergy Clin Immunol 2018; 142 (2):699-702.e12 A kindred with mutant IKAROS and autoimmunity.
Alhakeem SS et al. J Immunol 2018; 200 (12):4180-4189 Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity.
Li C et al. Mol Ther Methods Clin Dev 2018; 9:390-401 HDAd5/35++ Adenovirus Vector Expressing Anti-CRISPR Peptides Decreases CRISPR/Cas9 Toxicity in Human Hematopoietic Stem Cells.
Mielle J et al. Front Immunol 2018; 9:961 IL-10 Producing B Cells Ability to Induce Regulatory T Cells Is Maintained in Rheumatoid Arthritis.
Charlesworth CT et al. Mol Ther Nucleic Acids 2018; 12:89-104 Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting.
Verney A et al. Oncotarget 2018; 9 (34):23589-23598 Toll-like receptor expression and function differ between splenic marginal zone B cell lymphoma and splenic diffuse red pulp B cell lymphoma.
Murray LW et al. J Infect Dis 2018; 217 (11):1782-1792 Human Immunodeficiency Virus Infection Impairs Th1 and Th17 Mycobacterium tuberculosis-Specific T-Cell Responses.
Rajasekhar M et al. Sci Rep 2018; 8 (1):7264 Identifying microRNA determinants of human myelopoiesis.
Cooles FAH et al. Front Immunol 2018; 9:755 Phenotypic and Transcriptomic Analysis of Peripheral Blood Plasmacytoid and Conventional Dendritic Cells in Early Drug Na?ve Rheumatoid Arthritis.
Huang H et al. Clin Immunol 2018; 193:1-9 23-valent pneumococcal polysaccharide vaccine elicits hierarchical antibody and cellular responses in healthy and tuberculosis-cured elderly, and HIV-1-infected subjects.
Heukels P et al. Respir Res 2018; 19 (1):90 Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis.
Shinde R et al. Nat Immunol 2018; 19 (6):571-582 Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans.
Risnes LF et al. J Clin Invest 2018; 128 (6):2642-2650 Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease.
Hill DA et al. Proc Natl Acad Sci U S A 2018; 115 (22):E5096-E5105 Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue.
Kagoya Y et al. Nat Commun 2018; 9 (1):1915 DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models.
Bengsch B et al. Immunity 2018; 48 (5):1029-1045.e5 Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8?T Cells.
Zhong J et al. Sci Adv 2018; 4 (5):eaas9864 Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes.
Vogt MB et al. PLoS Negl Trop Dis 2018; 12 (5):e0006439 Mosquito saliva alone has profound effects on the human immune system.
Garc?a-Peydr? M et al. J Clin Invest 2018; 128 (7):2802-2818 The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model.
Frobel J et al. Clin Epigenetics 2018; 10:67 Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice.
Kaur S et al. Front Physiol 2018; 9:556 Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in Patients With Alcoholic Liver Cirrhosis.
Abolhalaj M et al. Sci Rep 2018; 8 (1):8030 Profiling dendritic cell subsets in head and neck squamous cell tonsillar cancer and benign tonsils.
Iwabuchi R et al. Front Immunol 2018; 9:1042 Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells.
Wallin EF et al. Front Immunol 2018; 9:1184 The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells.
Young PA et al. J Interferon Cytokine Res 2018; 38 (6):239-254 Activity of Anti-CD19 Chimeric Antigen Receptor T Cells Against B Cell Lymphoma Is Enhanced by Antibody-Targeted Interferon-Alpha.
Antonarakis ES et al. Clin Cancer Res 2018; 24 (19):4662-4671 Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival.
Balasubramaniam S et al. Anticancer Drugs 2018; 29 (5):457-465
Lingblom CMD et al. J Transl Med 2018; 16 (1):153 Baseline immune profile by CyTOF can predict response to an investigational adjuvanted vaccine in elderly adults.
Laverdi?re I et al. Blood Cancer J 2018; 8 (6):52 Leukemic stem cell signatures identify novel therapeutics targeting acute myeloid leukemia.
Costa-Pereira C et al. PLoS Negl Trop Dis 2018; 12 (6):e0006462 Multi-parameter approach to evaluate the timing of memory status after 17DD-YF primary vaccination.
Waight JD et al. Cancer Cell 2018; 33 (6):1033-1047.e5 Selective FcγR Co-engagement on APCs Modulates the Activity of Therapeutic Antibodies Targeting T?Cell Antigens.
Zappasodi R et al. Cancer Cell 2018; 33 (6):1017-1032.e7 Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.
Setliff I et al. Cell Host Microbe 2018; 23 (6):845-854.e6 Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection.
Perico N et al. Front Immunol 2018; 9:1359 Long-Term Clinical and Immunological Profile of Kidney Transplant Patients Given Mesenchymal Stromal Cell Immunotherapy.
Frey-Jakobs S et al. Sci Immunol 2018; 3 (24) ZNF341 controls STAT3 expression and thereby immunocompetence.
Haltaufderhyde K et al. J Infect Dis 2018; 218 (10):1675-1685 Activation of Peripheral T Follicular Helper Cells During Acute Dengue Virus Infection.
Moysi E et al. J Clin Invest 2018; 128 (7):3171-3185 Altered immune cell follicular dynamics in HIV infection following influenza vaccination.
Bluhm J et al. Mol Ther 2018; 26 (8):1906-1920 CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma.
Hirota K et al. Immunity 2018; 48 (6):1220-1232.e5 Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Kirkling ME et al. Cell Rep 2018; 23 (12):3658-3672.e6 Notch Signaling Facilitates In?Vitro Generation of Cross-Presenting Classical Dendritic Cells.
Friedensohn S et al. Front Immunol 2018; 9:1401 Synthetic Standards Combined With Error and Bias Correction Improve the Accuracy and Quantitative Resolution of Antibody Repertoire Sequencing in Human Na?ve and Memory B Cells.
Piper CJM et al. Front Immunol 2018; 9:1372 CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α.
Zhang Y et al. Front Cell Neurosci 2018; 12:170 Association Between Programed Cell Death-1 and CD4+ T Cell Alterations in Different Phases of Ischemic Stroke Patients.
Porichis F et al. J Immunol 2018; 201 (3):971-981 Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells.
Renand A et al. Front Immunol 2018; 9:1408 Heterogeneity of Ara h Component-Specific CD4 T Cell Responses in Peanut-Allergic Subjects.
Chu C et al. Cell Rep 2018; 23 (13):3750-3758 Anti-microbial Functions of Group 3 Innate Lymphoid Cells in Gut-Associated Lymphoid Tissues Are Regulated by G-Protein-Coupled Receptor 183.
Miggelbrink AM et al. Blood 2018; 131 (26):2967-2977 B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation.
Dolton G et al. Front Immunol 2018; 9:1378 Optimized Peptide-MHC Multimer Protocols for Detection and Isolation of Autoimmune T-Cells.
Rosenfeld AM et al. Front Immunol 2018; 9:1472 Computational Evaluation of B-Cell Clone Sizes in Bulk Populations.
Lawless D et al. Front Immunol 2018; 9:1527 A Case of Adult-Onset Still's Disease Caused by a Novel Splicing Mutation in TNFAIP3 Successfully Treated With Tocilizumab.
Rossetti RAM et al. PLoS One 2018; 13 (7):e0199034 B lymphocytes can be activated to act as antigen presenting cells to promote anti-tumor responses.
Duggal NA et al. Sci Rep 2018; 8 (1):10186 Innate and adaptive immune dysregulation in critically ill ICU patients.
Ngom M et al. Mol Ther Methods Clin Dev 2018; 10:156-164 UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells.
Zhao M et al. Nat Commun 2018; 9 (1):2627 Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70.
Yarzabek B et al. Elife 2018; 7 Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity.
Amici SA et al. Front Immunol 2018; 9:1593 CD38 Is Robustly Induced in Human Macrophages and Monocytes in Inflammatory Conditions.
Donlin LT et al. Arthritis Res Ther 2018; 20 (1):139 Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
Lertjuthaporn S et al. PLoS One 2018; 13 (7):e0200564 Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection.
Hu Y et al. Arthritis Rheumatol 2018; 70 (8):1331-1342 Development of a Molecular Signature to Monitor Pharmacodynamic Responses Mediated by In Vivo Administration of Glucocorticoids.
Kim L et al. JCI Insight 2018; 3 (13) Safety and immunogenicity of an oral tablet norovirus vaccine, a phase I randomized, placebo-controlled trial.
Tasaki S et al. Nat Commun 2018; 9 (1):2755 Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission.
Huang X et al. Nat Commun 2018; 9 (1):2741 Neutralizing negative epigenetic regulation by HDAC5 enhances human haematopoietic stem cell homing and engraftment.
Yeo L et al. J Clin Invest 2018; 128 (8):3460-3474 Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes.
Kiener R et al. J Virol 2018; 92 (15) Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors.
Tanaka K et al. Oncotarget 2018; 9 (55):30587-30593 Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade.
Blum LK et al. Front Immunol 2018; 9:1634 Robust B Cell Responses Predict Rapid Resolution of Lyme Disease.
Hirata F et al. Ann Gastroenterol Surg 2018; 2 (5):383-393 Effect of bevacizumab plus XELOX (CapeOX) chemotherapy on liver natural killer cell activity in colorectal cancer with resectable liver metastasis.
Salzberger W et al. PLoS One 2018; 13 (7):e0201170 Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71.
Stein J et al. Front Neurol 2018; 9:554 Intrathecal B Cells in MS Have Significantly Greater Lymphangiogenic Potential Compared to B Cells Derived From Non-MS Subjects.
Kim ST et al. J Immunol 2018; 201 (5):1359-1372 Human Extrafollicular CD4+ Th Cells Help Memory B Cells Produce Igs.
Tarique M et al. Front Immunol 2018; 9:1636 Interleukin-10 Producing Regulatory B Cells Transformed CD4+CD25- Into Tregs and Enhanced Regulatory T Cells Function in Human Leprosy.
Li M et al. PLoS One 2018; 13 (7):e0200478 Dengue immune sera enhance Zika virus infection in human peripheral blood monocytes through Fc gamma receptors.
Heshmati Y et al. Sci Rep 2018; 8 (1):11202 The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation.
Margolin K et al. Clin Cancer Res 2018; 24 (22):5552-5561 Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors.
Mieczkowska A et al. Sci Rep 2018; 8 (1):11339 Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells.
Achita P et al. Clin Exp Immunol 2018; 193 (3):386-399 Infusion of ex-vivo expanded human TCR-αβ+ double-negative regulatory T cells delays onset of xenogeneic graft-versus-host disease.
Bowyer G et al. Vaccines (Basel) 2018; 6 (3) Activation-induced Markers Detect Vaccine-Specific CD4? T Cell Responses Not Measured by Assays Conventionally Used in Clinical Trials.
Robinson HR et al. Blood 2018; 132 (5):521-532 A CD19/CD3 bispecific antibody for effective immunotherapy of chronic lymphocytic leukemia in the ibrutinib era.
Seo GY et al. Cell Host Microbe 2018; 24 (2):249-260.e4 LIGHT-HVEM Signaling in Innate Lymphoid Cell Subsets Protects Against Enteric Bacterial Infection.
Otsuki N et al. PLoS One 2018; 13 (8):e0201764 A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein.
Psatha N et al. Mol Ther Methods Clin Dev 2018; 10:313-326 Disruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia Major.
Tobin RP et al. Int Immunopharmacol 2018; 63:282-291 Targeting myeloid-derived suppressor cells using all-trans retinoic acid in melanoma patients treated with Ipilimumab.
Kong XF et al. Nat Immunol 2018; 19 (9):973-985 Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.
Bajor DL et al. Oncoimmunology 2018; 7 (10):e1468956 Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma.
Salter AI et al. Sci Signal 2018; 11 (544) Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.
Zhu YP et al. Cell Rep 2018; 24 (9):2329-2341.e8 Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow.
Agarwal D et al. Immun Ageing 2018; 15:19 Immune response to influenza vaccination in the elderly is altered by chronic medication use.
Yamaguchi K et al. Cancer Sci 2018; 109 (10):3032-3042 Activation of central/effector memory T cells and T-helper 1 polarization in malignant melanoma patients treated with anti-programmed death-1 antibody.
Dam EM et al. Front Immunol 2018; 9:1978 Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis.
Backes CS et al. J Biol Chem 2018; 293 (42):16348-16363 Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms.
Habets THPM et al. PLoS One 2018; 13 (9):e0203381 The prevalence of antibodies against the HLA-DRB3 protein in kidney transplantation and the correlation with HLA expression.
Hamilton JA et al. J Immunol 2018; 201 (8):2203-2208 Cutting Edge: Intracellular IFN-β and Distinct Type I IFN Expression Patterns in Circulating Systemic Lupus Erythematosus B Cells.
Aschenbrenner D et al. Nat Immunol 2018; 19 (10):1126-1136 An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells.
Nam HW et al. Clin Exp Immunol 2018; 194 (1):125-136 Functional status of immune cells in patients with long-lasting type 2 diabetes mellitus.
Lundy SK et al. Front Med (Lausanne) 2018; 5:249 T Helper 1 Cellular Immunity Toward Recoverin Is Enhanced in Patients With Active Autoimmune Retinopathy.
Jelcic I et al. Cell 2018; 175 (1):85-100.e23 Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis.
Chan CKF et al. Cell 2018; 175 (1):43-56.e21 Identification of the Human Skeletal Stem Cell.
James NE et al. Clin Exp Immunol 2018; 193 (3):327-340 HE4 suppresses the expression of osteopontin in mononuclear cells and compromises their cytotoxicity against ovarian cancer cells.
Sung JA et al. Mol Ther 2018; 26 (10):2496-2506 HIV-Specific, Ex?Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals.
Noto A et al. J Virol 2018; 92 (20) CD32+ and PD-1+ Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals.
Nakano M et al. Cancer Sci 2018; 109 (11):3461-3470 Epithelial-mesenchymal transition is activated in CD44-positive malignant ascites tumor cells of gastrointestinal cancer.
Zacca ER et al. Front Immunol 2018; 9:2241 PD-L1+ Regulatory B Cells Are Significantly Decreased in Rheumatoid Arthritis Patients and Increase After Successful Treatment.
Ruella M et al. Nat Med 2018; 24 (10):1499-1503 Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell.
Smith CC et al. J Clin Invest 2018; 128 (11):4804-4820 Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma.
Shan M et al. Immunity 2018; 49 (4):709-724.e8 Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.
Bradley T et al. Cell 2018; 175 (2):387-399.e17 RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.
Poe JC et al. JCI Insight 2018; 3 (19) SYK inhibitor entospletinib prevents ocular and skin GVHD in mice.
Belluschi S et al. Nat Commun 2018; 9 (1):4100 Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors.
Zhang W et al. Drug Des Devel Ther 2018; 12:3343-3356 Characterization of clinical grade CD19 chimeric antigen receptor T cells produced using automated CliniMACS Prodigy system.
Meurer T et al. Front Immunol 2018; 9:2236 Dissecting Genetic Control of HLA-DPB1 Expression and Its Relation to Structural Mismatch Models in Hematopoietic Stem Cell Transplantation.
Rotolo A et al. Cancer Cell 2018; 34 (4):596-610.e11 Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting.
Chow KT et al. J Immunol 2018; 201 (10):3036-3050 Differential and Overlapping Immune Programs Regulated by IRF3 and IRF5 in Plasmacytoid Dendritic Cells.
Zissler UM et al. EBioMedicine 2018; 36:475-488 Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT.
Garc?a-Rubio J et al. Sci Rep 2018; 8 (1):15203 Cytometric analysis of adipose tissue reveals increments of adipocyte progenitor cells after weight loss induced by bariatric surgery.
Otsuka Y et al. J Immunol 2018; 201 (10):3006-3016 Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells.
Lagou V et al. Cell Rep 2018; 25 (3):798-810.e6 Genetic Architecture of Adaptive Immune System Identifies Key Immune Regulators.
Deng M et al. Nature 2018; 562 (7728):605-609 LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.
Annunziata P et al. Sci Rep 2018; 8 (1):15371 Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients.
Moreira D et al. Clin Cancer Res 2018; 24 (23):5948-5962 STAT3 Inhibition Combined with CpG Immunostimulation Activates Antitumor Immunity to Eradicate Genetically Distinct Castration-Resistant Prostate Cancers.
Kaur S et al. Sci Rep 2018; 8 (1):15503 Small non-coding RNA landscape of extracellular vesicles from human stem cells.
Skovdahl HK et al. Int J Mol Sci 2018; 19 (10) C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release.
Elliott SE et al. Arthritis Rheumatol 2018; 70 (12):1946-1958 Affinity Maturation Drives Epitope Spreading and Generation of Proinflammatory Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis.
Cheng WC et al. Clin Exp Immunol 2018; 194 (3):380-390 Comparative analysis of immune cell subsets in peripheral blood from patients with periodontal disease and healthy controls.
Harms RZ et al. Front Immunol 2018; 9:2332 Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes.
Agrawal N et al. Front Immunol 2018; 9:2417 Human Monocytic Suppressive Cells Promote Replication of Mycobacterium tuberculosis and Alter Stability of in vitro Generated Granulomas.
Belarif L et al. Nat Commun 2018; 9 (1):4483 IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.
Summerauer AM et al. Malar J 2018; 17 (1):395 High purity high yield tandem B and T helper cell isolation for qRT-PCR analysis suitable for basically equipped laboratories.
Knier B et al. Nat Immunol 2018; 19 (12):1341-1351 Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity.
Yen J et al. Sci Rep 2018; 8 (1):16304 TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells.
Shastri A et al. J Clin Invest 2018; 128 (12):5479-5488 Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells.
Olson GS et al. Sci Rep 2018; 8 (1):16471 Increased frequency of systemic pro-inflammatory Vδ1+ γδ T cells in HIV elite controllers correlates with gut viral load.
Rodrigues-Santos P et al. Front Immunol 2018; 9:2587 Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors.
Leibler C et al. J Clin Med 2018; 7 (11) Rituximab and Fibrillary Glomerulonephritis: Interest of B Cell Reconstitution Monitoring.
Saraiva DP et al. Front Immunol 2018; 9:2605 HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy.
Savage TM et al. JCI Insight 2018; 3 (22) Early expansion of donor-specific Tregs in tolerant kidney transplant recipients.
Barruet E et al. JCI Insight 2018; 3 (22) NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification.
Rathore DK et al. PLoS One 2018; 13 (11):e0207297 Differences in multiple immune parameters between Indian and U.S. infants.
Delcroix M et al. Pathog Dis 2018; 76 (8) Flow-cytometric analysis of human monocyte subsets targeted by Mycobacterium bovis BCG before granuloma formation.
Joo EJ et al. Sci Rep 2018; 8 (1):17174 Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein.
Kuri-Maga?a H et al. Front Immunol 2018; 9:2679 Non-coding Class Switch Recombination-Related Transcription in Human Normal and Pathological Immune Responses.
Mukherjee N et al. Oncotarget 2018; 9 (92):36492-36502 Intratumoral CD56bright natural killer cells are associated with improved survival in bladder cancer.
Pu X et al. J Transl Med 2018; 16 (1):328 Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer.
Osorio FG et al. Cell Rep 2018; 25 (9):2308-2316.e4 Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis.
Douam F et al. Nat Commun 2018; 9 (1):5031 Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses.
Baglaenko Y et al. Arthritis Res Ther 2018; 20 (1):264 The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease.
Ott CJ et al. Cancer Cell 2018; 34 (6):982-995.e7 Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia.
Chee J et al. BMC Res Notes 2018; 11 (1):864 Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors.
Magill L et al. Front Immunol 2018; 9:2865 Low Percentage of Signal Regulatory Protein α/β+ Memory B Cells in Blood Predicts Development of Anti-drug Antibodies (ADA) in Adalimumab-Treated Rheumatoid Arthritis Patients.
van Zyl DG et al. PLoS Pathog 2018; 14 (12):e1007464 Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.
Tran HTT et al. Front Immunol 2018; 9:2949 Human T2R38 Bitter Taste Receptor Expression in Resting and Activated Lymphocytes.
Castellanos JG et al. Immunity 2018; 49 (6):1077-1089.e5 Microbiota-Induced TNF-like Ligand 1A Drives Group 3 Innate Lymphoid Cell-Mediated Barrier Protection and Intestinal T Cell Activation during Colitis.
Lee SY et al. Front Immunol 2018; 9:2881 The Therapeutic Effect of STAT3 Signaling-Suppressed MSC on Pain and Articular Cartilage Damage in a Rat Model of Monosodium Iodoacetate-Induced Osteoarthritis.
Burbano C et al. Sci Rep 2018; 8 (1):17917 Extracellular vesicles are associated with the systemic inflammation of patients with seropositive rheumatoid arthritis.
He W et al. Immunity 2018; 49 (6):1175-1190.e7 Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues.
Kwon M et al. Immune Netw 2018; 18 (6):e45 Two-Round Mixed Lymphocyte Reaction for Evaluation of the Functional Activities of Anti-PD-1 and Immunomodulators.
Skibinski DAG et al. Sci Rep 2018; 8 (1):18007 Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine.
Bhaumik SK et al. Viruses 2018; 11 (1) Pre-Existing Dengue Immunity Drives a DENV-Biased Plasmablast Response in ZIKV-Infected Patient.
Passos LSA et al. Front Immunol 2018; 9:3015 Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease.
Fergusson JR et al. Front Immunol 2018; 9:2902 Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens.
Hood SP et al. Front Immunol 2018; 9:3169 Phenotype and Function of Activated Natural Killer Cells From Patients With Prostate Cancer: Patient-Dependent Responses to Priming and IL-2 Activation.
Tomiyama T et al. Cell Mol Immunol 2017; 14 (3):276-284 The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis.
Selb R et al. J Allergy Clin Immunol 2017; 139 (1):290-299.e4 CD23 surface density on B?cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T?cells.
Burton OT et al. J Allergy Clin Immunol 2017; 139 (1):314-322.e9 A humanized mouse model of anaphylactic peanut allergy.
Bharadwaj AS et al. Ocul Immunol Inflamm 2017; 25 (6):811-819 Molecular Signals Involved in Human B Cell Migration into the Retina: In Vitro Investigation of ICAM-1, VCAM-1, and CXCL13.
Wege AK et al. Oncotarget 2017; 8 (2):2731-2744 IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM).
Svoronos N et al. Cancer Discov 2017; 7 (1):72-85 Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.
Peperzak V et al. Cell Death Differ 2017; 24 (1):111-119 Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling.
Svensson A et al. J Neurooncol 2017; 131 (2):245-254 Identification of two distinct mesenchymal stromal cell populations in human malignant glioma.
Sierzega M et al. Ann Surg Oncol 2017; 24 (3):808-815 Preoperative Neutrophil-Lymphocyte and Lymphocyte-Monocyte Ratios Reflect Immune Cell Population Rearrangement in Resectable Pancreatic Cancer.
Fenton TM et al. Mucosal Immunol 2017; 10 (3):624-634 Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8.
Li X et al. Expert Rev Vaccines 2017; 16 (1):73-80 A potent adjuvant effect of a CD1d-binding NKT cell ligand in human immune system mice.
Achard C et al. Oncoimmunology 2017; 6 (1):e1261240 Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells.
Gosselin A et al. AIDS 2017; 31 (1):35-48 HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy.
Jab?o?ski M et al. Stem Cell Rev Rep 2017; 13 (2):217-225 Mobilization of Peripheral Blood Stem Cells and Changes in the Concentration of Plasma Factors Influencing their Movement in Patients with Panic Disorder.
Michels AW et al. Diabetes 2017; 66 (3):722-734 Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
Spitsin S et al. J Leukoc Biol 2017; 101 (4):967-973 Substance P-mediated chemokine production promotes monocyte migration.
Huang B et al. Nat Med 2017; 23 (1):128-135 Interleukin-33-induced expression of PIBF1 by decidual B cells protects against preterm labor.
Lu Z et al. Nat Med 2017; 23 (1):79-90 Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.
Cheeseman HM et al. J Virol 2017; 91 (1) Broadly Neutralizing Antibodies Display Potential for Prevention of HIV-1 Infection of Mucosal Tissue Superior to That of Nonneutralizing Antibodies.
Baughn LB et al. Leuk Lymphoma 2017; 58 (8):1931-1940 Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry.
Hasan S et al. Am J Physiol Cell Physiol 2017; 312 (3):C286-C301 Myelo-erythroid commitment after burn injury is under β-adrenergic control via MafB regulation.
Rodr?guez-Carrio J et al. Arthritis Rheumatol 2017; 69 (1):70-76 Brief Report: Altered Innate Lymphoid Cell Subsets in Human Lymph Node Biopsy Specimens Obtained During the At-Risk and Earliest Phases of Rheumatoid Arthritis.
Li J et al. Toxicology 2017; 378:17-24 Aryl hydrocarbon receptor activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs human B lymphopoiesis.
Nicholas KJ et al. J Acquir Immune Defic Syndr 2017; 74 (1):72-80 Chronic HIV-1 Infection Impairs Superantigen-Induced Activation of Peripheral CD4+CXCR5+PD-1+ Cells, With Relative Preservation of Recall Antigen-Specific Responses.
Kalampokis I et al. Arthritis Rheumatol 2017; 69 (1):225-238 The Regulatory B Cell Compartment Expands Transiently During Childhood and Is Contracted in Children With Autoimmunity.
Izawa K et al. J Exp Med 2017; 214 (1):73-89 Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection.
Tsuchida Y et al. PLoS One 2017; 12 (1):e0169646 TGF-β3 Inhibits Antibody Production by Human B Cells.
Dalli J et al. Immunity 2017; 46 (1):92-105 Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution.
Maetzig T et al. Mol Ther 2017; 25 (3):606-620 A Lentiviral Fluorescent Genetic Barcoding System for Flow Cytometry-Based Multiplex Tracking.
Guo A et al. Oncotarget 2017; 8 (8):12953-12967 Dual SYK/JAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia: Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment.
Hale M et al. Mol Ther Methods Clin Dev 2017; 4:192-203 Homology-Directed Recombination for Enhanced Engineering of Chimeric Antigen Receptor T Cells.
Chao MP et al. Cell Stem Cell 2017; 20 (3):329-344.e7 Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.
Tauriainen J et al. Sci Rep 2017; 7:40354 Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.
Vander Heiden JA et al. J Immunol 2017; 198 (4):1460-1473 Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.
Beyer AI et al. Stem Cells Dev 2017; 26 (2):102-112 Comparison of Human Hematopoietic Reconstitution in Different Strains of Immunodeficient Mice.
Aw Yeang HX et al. J Immunol 2017; 198 (4):1417-1422 Cutting Edge: Human CD49e- NK Cells Are Tissue Resident in the Liver.
Williams CR et al. BMC Bioinformatics 2017; 18 (1):38 Empirical assessment of analysis workflows for differential expression analysis of human samples using RNA-Seq.
Hector SM et al. Clin Ophthalmol 2017; 11:179-184 Circulating monocytes and B-lymphocytes in neovascular age-related macular degeneration.
Baratella M et al. PLoS Negl Trop Dis 2017; 11 (1):e0005285 Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
Liu X et al. Genome Biol 2017; 18 (1):4 Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus.
Aravena O et al. Arthritis Res Ther 2017; 19 (1):8 TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients.
Aagaard KM et al. Sci Rep 2017; 7:41389 Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication.
Calderon TM et al. J Neuroimmune Pharmacol 2017; 12 (2):353-370 Dopamine Increases CD14+CD16+ Monocyte Transmigration across the Blood Brain Barrier: Implications for Substance Abuse and HIV Neuropathogenesis.
O'Connor D et al. Genome Med 2017; 9 (1):11 High-dimensional assessment of B-cell responses to quadrivalent meningococcal conjugate and plain polysaccharide vaccine.
Thobakgale C et al. J Acquir Immune Defic Syndr 2017; 74 (2):213-220 Interleukin 1-Beta (IL-1β) Production by Innate Cells Following TLR Stimulation Correlates With TB Recurrence in ART-Treated HIV-Infected Patients.
Rao DA et al. Nature 2017; 542 (7639):110-114 Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Sharma M et al. Indian J Med Res 2017; 145 (2):215-221 Haematological profile of patients with mixed-phenotype acute leukaemia from a tertiary care centre of north India.
Kadi? E et al. BMC Immunol 2017; 18 (1):6 Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determinated by multiparametric single cell mass cytometry analysis.
Riedel JH et al. J Am Soc Nephrol 2017; 28 (7):2068-2080 IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis.
Crome SQ et al. Nat Med 2017; 23 (3):368-375 A distinct innate lymphoid cell population regulates tumor-associated T cells.
Picarda E et al. JCI Insight 2017; 2 (3):e90088 Transient antibody targeting of CD45RC induces transplant tolerance and potent antigen-specific regulatory T cells.
Smulski CR et al. Cell Death Dis 2017; 8 (2):e2601 Hetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signalling.
Yi JS et al. Front Neurol 2017; 8:34 B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity.
Pereira I et al. Front Pharmacol 2017; 8:53 Transient Receptor Potential Ankyrin 1 Channel Expression on Peripheral Blood Leukocytes from Rheumatoid Arthritic Patients and Correlation with Pain and Disability.
Angelo MA et al. J Virol 2017; 91 (5) Human CD4+ T Cell Responses to an Attenuated Tetravalent Dengue Vaccine Parallel Those Induced by Natural Infection in Magnitude, HLA Restriction, and Antigen Specificity.
Shikhagaie MM et al. Cell Rep 2017; 18 (7):1761-1773 Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates.
Moy RH et al. Blood 2017; 129 (7):906-916 Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis.
Spencer DH et al. Cell 2017; 168 (5):801-816.e13 CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.
Requena P et al. Front Immunol 2017; 8:163 Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study.
Ryzhov S et al. Am J Physiol Heart Circ Physiol 2017; 312 (5):H907-H918 ERBB signaling attenuates proinflammatory activation of nonclassical monocytes.
Chaturvedi A et al. Leukemia 2017; 31 (10):2020-2028 Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.
Flerin NC et al. J Virol 2017; 91 (6) T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone.
Fresnay S et al. Front Immunol 2017; 8:208 Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model.
Corleis B et al. PLoS One 2017; 12 (3):e0173161 Early type I Interferon response induces upregulation of human β-defensin 1 during acute HIV-1 infection.
Guo B et al. Nat Med 2017; 23 (4):424-428 Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment.
Esteve-Sol? A et al. Front Immunol 2017; 8:201 Characterization of the Highly Prevalent Regulatory CD24hiCD38hi B-Cell Population in Human Cord Blood.
Fischer K et al. Front Immunol 2017; 8:202 The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells.
Hoff P et al. Int J Mol Sci 2017; 18 (3) A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients.
Collins A et al. JCI Insight 2017; 2 (5):e90063 Eomesodermin and T-bet mark developmentally distinct human natural killer cells.
Singh AK et al. Front Immunol 2017; 8:260 High Interferon-γ Uniquely in Vδ1 T Cells Correlates with Markers of Inflammation and Axonal Damage in Early Multiple Sclerosis.
Effner R et al. Sci Rep 2017; 7:44005 Cytochrome P450s in human immune cells regulate IL-22 and c-Kit via an AHR feedback loop.
Souza-Fonseca-Guimaraes P et al. Int J Mol Sci 2017; 18 (3) Natural Killer Cell Assessment in Peripheral Circulation and Bronchoalveolar Lavage Fluid of Patients with Severe Sepsis: A Case Control Study.
Higdon LE et al. Am J Transplant 2017; 17 (8):2045-2054 Cytomegalovirus-Responsive CD8+ T Cells Expand After Solid Organ Transplantation in the Absence of CMV Disease.
Paris RM et al. Pathog Immun 2017; 2 (1):66-88 Lower Baseline Germinal Center Activity and Preserved Th1 Immunity Are Associated With Hepatitis B Vaccine Response in Treated HIV Infection.
Fuchs YF et al. Sci Rep 2017; 7:44661 CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage.
Lu X et al. Nature 2017; 543 (7647):728-732 Effective combinatorial immunotherapy for castration-resistant prostate cancer.
Tsoneva D et al. Mol Ther Oncolytics 2017; 5:41-61 Humanized Mice with Subcutaneous Human Solid Tumors for Immune Response Analysis of Vaccinia Virus-Mediated Oncolysis.
Seong Y et al. JCI Insight 2017; 2 (6):e90233 Trafficking receptor signatures define blood plasmablasts responding to tissue-specific immune challenge.
Nouri-Shirazi M et al. BMC Vet Res 2017; 13 (1):78 Phenotyping and comparing the immune cell populations of free-ranging Atlantic bottlenose dolphins (Tursiops truncatus) and dolphins under human care.
Hamada S et al. Open J Immunol 2017; 7 (1):1-17 Soluble MICB in Plasma and Urine Explains Population Expansions of NKG2D+CD4 T Cells Inpatients with Juvenile-Onset Systemic Lupus Erythematosus.
Collins PJ et al. FASEB J 2017; 31 (7):3084-3097 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.
Camelo A et al. Blood Adv 2017; 1 (10):577-589 IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells.
Lopes FB et al. J Cell Biol 2017; 216 (4):1123-1141 Membrane nanoclusters of FcγRI segregate from inhibitory SIRPα upon activation of human macrophages.
Dallari S et al. Nat Commun 2017; 8:14830 Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses.
West NR et al. Nat Med 2017; 23 (5):579-589 Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease.
Seet CS et al. Nat Methods 2017; 14 (5):521-530 Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids.
Lima JF et al. Sci Rep 2017; 7 (1):524 Polyfunctional natural killer cells with a low activation profile in response to Toll-like receptor 3 activation in HIV-1-exposed seronegative subjects.
Bruce DW et al. J Clin Invest 2017; 127 (5):1813-1825 Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease.
Gies V et al. Sci Rep 2017; 7 (1):602 Identification of autoreactive B cells with labeled nucleosomes.
Zheng Q et al. Mol Oncol 2017; 11 (5):584-594 Diphtheria toxin-based anti-human CD19 immunotoxin for targeting human CD19+ tumors.
Nevala WK et al. Sci Rep 2017; 7:45682
Salerno-Goncalves R et al. Front Immunol 2017; 8:398 Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells.
Rupp LJ et al. Sci Rep 2017; 7 (1):737 CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.
M?ller MM et al. Sci Rep 2017; 7 (1):838 Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression.
Chassaing B et al. Cell Mol Gastroenterol Hepatol 2017; 4 (2):205-221 Colonic Microbiota Encroachment Correlates With Dysglycemia in Humans.
Deng C et al. J Diabetes Res 2017; 2017:5052812 The Imbalance of B-Lymphocyte Subsets in Subjects with Different Glucose Tolerance: Relationship with Metabolic Parameter and Disease Status.
Cottineau J et al. J Clin Invest 2017; 127 (5):1991-2006 Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.
Linedale R et al. PLoS One 2017; 12 (4):e0175755 Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients.
Knox JJ et al. JCI Insight 2017; 2 (8) T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response.
Adamczyk A et al. JCI Insight 2017; 2 (8) Differential expression of GPR15 on T cells during ulcerative colitis.
Crawford LB et al. Sci Rep 2017; 7 (1):937 Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.
Xu Y et al. Front Immunol 2017; 8:376 HIV-1 and SIV Predominantly Use CCR5 Expressed on a Precursor Population to Establish Infection in T Follicular Helper Cells.
Vladimer GI et al. Nat Chem Biol 2017; 13 (6):681-690 Global survey of the immunomodulatory potential of common drugs.
Darboe A et al. Eur J Immunol 2017; 47 (6):1040-1050 Enhancement of cytokine-driven NK cell IFN-γ production after vaccination of HCMV infected Africans.
Yang D et al. Sci Rep 2017; 7 (1):1288 NKG2D+CD4+ T Cells Kill Regulatory T Cells in a NKG2D-NKG2D Ligand- Dependent Manner in Systemic Lupus Erythematosus.
Manion M et al. PLoS One 2017; 12 (5):e0175517 Vitamin D deficiency is associated with IL-6 levels and monocyte activation in HIV-infected persons.
Pryke KM et al. mBio 2017; 8 (3) A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses.
Eitan E et al. Sci Rep 2017; 7 (1):1342 Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes.
Schoenhals M et al. Cell Cycle 2017; 16 (11):1104-1117 Hypoxia favors the generation of human plasma cells.
Wieland D et al. Nat Commun 2017; 8:15050 TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation.
Budde H et al. Cent Eur J Immunol 2017; 42 (1):1-9 In vitro effects of different 8-methoxypsoralen treatment protocols for extracorporeal photopheresis on mononuclear cells.
Lord JD et al. World J Gastroenterol 2017; 23 (18):3240-3251 Thiopurine use associated with reduced B and natural killer cells in inflammatory bowel disease.
Nakachi S et al. Arthritis Res Ther 2017; 19 (1):97 Interleukin-10-producing LAG3+ regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis.
Cale EM et al. Immunity 2017; 46 (5):777-791.e10 Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop.
Euteneuer F et al. Transl Psychiatry 2017; 7 (5):e1132 Immunological effects of behavioral activation with exercise in major depression: an exploratory randomized controlled trial.
Xu L et al. Mol Ther 2017; 25 (8):1782-1789 CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In?Vivo.
Sugimura R et al. Nature 2017; 545 (7655):432-438 Haematopoietic stem and progenitor cells from human pluripotent stem cells.
Sharma M et al. Sci Rep 2017; 7 (1):2085 Inhibition of endocytic lipid antigen presentation by common lipophilic environmental pollutants.
Penatti A et al. Arthritis Res Ther 2017; 19 (1):103 Differences in serum and synovial CD4+ T cells and cytokine profiles to stratify patients with inflammatory osteoarthritis and rheumatoid arthritis.
Afzali B et al. Nat Immunol 2017; 18 (7):813-823 BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.
Sandri S et al. Oncotarget 2017; 8 (50):86987-87001 Effective control of acute myeloid leukaemia and acute lymphoblastic leukaemia progression by telomerase specific adoptive T-cell therapy.
Chapel A et al. Sci Rep 2017; 7 (1):2414 Peptide-specific engagement of the activating NK cell receptor KIR2DS1.
Vujkovic-Cvijin I et al. Gut Microbes 2017; 8 (5):440-450 Limited engraftment of donor microbiome via one-time fecal microbial transplantation in treated HIV-infected individuals.
Jones AP et al. Clin Transl Immunology 2017; 6 (5):e143 Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis.
Shoda H et al. Arthritis Res Ther 2017; 19 (1):111 Increased serum concentrations of IL-1 beta, IL-21 and Th17 cells in overweight patients with rheumatoid arthritis.
Cerosaletti K et al. J Immunol 2017; 199 (1):323-335 Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+ T Cells in Peripheral Blood of Subjects with Type 1 Diabetes.
Vo TT et al. Mol Cancer Ther 2017; 16 (9):1942-1953 mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph+ and Ph-like B-ALL.
Loughland JR et al. Sci Rep 2017; 7 (1):2596 Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation.
Matsuoka Y et al. Cell Transplant 2017; 26 (6):1043-1058 CD34 Antigen and the MPL Receptor Expression Defines a Novel Class of Human Cord Blood-Derived Primitive Hematopoietic Stem Cells.
Cerboni S et al. J Exp Med 2017; 214 (6):1769-1785 Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes.
Karnell FG et al. Clin Exp Immunol 2017; 189 (3):268-278 Reconstitution of immune cell populations in multiple sclerosis patients after autologous stem cell transplantation.
Marcial GE et al. Front Immunol 2017; 8:655 Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults.
Wagner J et al. Front Immunol 2017; 8:676 A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma.
Rolland DCM et al. Proc Natl Acad Sci U S A 2017; 114 (25):6581-6586 Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas.
Yu M et al. Sci Rep 2017; 7 (1):3350 Fibroblastic reticular cells of the lymphoid tissues modulate T cell activation threshold during homeostasis via hyperactive cyclooxygenase-2/prostaglandin E2 axis.
Moguche AO et al. Cell Host Microbe 2017; 21 (6):695-706.e5 Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis.
Cho A et al. JCI Insight 2017; 2 (12) Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximab.
McDonnell AM et al. BMC Cancer 2017; 17 (1):417 Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters.
Trend S et al. Int J Mol Sci 2017; 18 (6) Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI.
M?tayer LE et al. Oncotarget 2017; 8 (37):60892-60903 Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis.
Ganesan AP et al. Nat Immunol 2017; 18 (8):940-950 Tissue-resident memory features are linked to the magnitude of cytotoxic T cell responses in human lung cancer.
Jourdan M et al. PLoS One 2017; 12 (6):e0179793 Characterization of human FCRL4-positive B cells.
Sulzer D et al. Nature 2017; 546 (7660):656-661 T cells from patients with Parkinson's disease recognize α-synuclein peptides.
Buranapraditkun S et al. J Virol 2017; 91 (14) Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers.
Lee J et al. Nat Immunol 2017; 18 (8):877-888 Lineage specification of human dendritic cells is marked by IRF8 expression in hematopoietic stem cells and multipotent progenitors.
Jiang X et al. Front Immunol 2017; 8:765 Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation.
Rutishauser RL et al. AIDS Res Hum Retroviruses 2017; 33 (7):658-667 Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression.
Patel AA et al. J Exp Med 2017; 214 (7):1913-1923 The fate and lifespan of human monocyte subsets in steady state and systemic inflammation.
Ott PA et al. Nature 2017; 547 (7662):217-221 An immunogenic personal neoantigen vaccine for patients with melanoma.
Zumwalde NA et al. JCI Insight 2017; 2 (13) Adoptively transferred Vγ9Vδ2 T cells show potent antitumor effects in a preclinical B cell lymphomagenesis model.
Fasbender F et al. Front Immunol 2017; 8:789 Differential Requirements for Src-Family Kinases in SYK or ZAP70-Mediated SLP-76 Phosphorylation in Lymphocytes.
Mou W et al. BMC Immunol 2017; 18 (1):36 γδTFH cells promote B cell maturation and antibody production in neuroblastoma.
Cant R et al. Front Immunol 2017; 8:809 Naltrexone Inhibits IL-6 and TNFα Production in Human Immune Cell Subsets following Stimulation with Ligands for Intracellular Toll-Like Receptors.
Wing JB et al. Proc Natl Acad Sci U S A 2017; 114 (31):E6400-E6409 A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers.
Cabrera CP et al. PLoS Med 2017; 14 (7):e1002352 Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study.
Johnson LE et al. J Immunother Cancer 2017; 5 (1):56 Pretreatment antigen-specific immunity and regulation - association with subsequent immune response to anti-tumor DNA vaccination.
Hazeldine J et al. PLoS Med 2017; 14 (7):e1002338 Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study.
Just SA et al. Respir Res 2017; 18 (1):141 Fibrocyte measurement in peripheral blood correlates with number of cultured mature fibrocytes in vitro and is a potential biomarker for interstitial lung disease in Rheumatoid Arthritis.
Magri G et al. Immunity 2017; 47 (1):118-134.e8 Human Secretory IgM Emerges from Plasma Cells Clonally Related to Gut Memory B Cells and Targets Highly Diverse Commensals.
Dai HS et al. Immunity 2017; 47 (1):159-170.e10 The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells.
Lirussi D et al. EBioMedicine 2017; 22:100-111 Type I IFN and not TNF, is Essential for Cyclic Di-nucleotide-elicited CTL by a Cytosolic Cross-presentation Pathway.
Guo Q et al. Sci Rep 2017; 7 (1):6627 Deformability based Cell Sorting using Microfluidic Ratchets Enabling Phenotypic Separation of Leukocytes Directly from Whole Blood.
Martinez-Varea A et al. J Perinat Med 2017; 45 (5):523-538 Clinical chorioamnionitis at term VII: the amniotic fluid cellular immune response.
Lunemann S et al. Sci Rep 2017; 7 (1):6676 Hobit expression by a subset of human liver-resident CD56bright Natural Killer cells.
Costa VV et al. mBio 2017; 8 (4) Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules.
Winkler MS et al. PLoS One 2017; 12 (8):e0182427 Human leucocyte antigen (HLA-DR) gene expression is reduced in sepsis and correlates with impaired TNFα response: A diagnostic tool for immunosuppression?
Burel JG et al. JCI Insight 2017; 2 (15) Dichotomous miR expression and immune responses following primary blood-stage malaria.
Ogunjimi B et al. J Clin Invest 2017; 127 (9):3543-3556 Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections.
Chitadze G et al. Oncoimmunology 2017; 6 (11):e1358839 In-depth immunophenotyping of patients with glioblastoma multiforme: Impact of steroid treatment.
Martrus G et al. PLoS One 2017; 12 (8):e0182532 Proliferative capacity exhibited by human liver-resident CD49a+CD25+ NK cells.
Rusconi M et al. Sci Rep 2017; 7 (1):7853 Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood.
Metzler G et al. J Immunol 2017; 199 (7):2249-2260 The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Yang M et al. Exp Ther Med 2017; 14 (4):3887-3893 CD19+CD24hiCD38hi regulatory B cells are associated with insulin resistance in type I Hashimoto's thyroiditis in Chinese females.
Booth JS et al. Cell Mol Gastroenterol Hepatol 2017; 4 (3):419-437 Systemic and Terminal Ileum Mucosal Immunity Elicited by Oral Immunization With the Ty21a Typhoid Vaccine in Humans.
Crespo J et al. Oncoimmunology 2017; 6 (12):e1362529 Phenotype and tissue distribution of CD28H+ immune cell subsets.
Leal Rojas IM et al. Front Immunol 2017; 8:971 Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells.
Gall VA et al. Cancer Res 2017; 77 (19):5374-5383 Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells.
Sanderson SL et al. Aging Cell 2017; 16 (6):1234-1243 In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay.
Ubillos I et al. Front Immunol 2017; 8:966 Chronic Exposure to Malaria Is Associated with Inhibitory and Activation Markers on Atypical Memory B Cells and Marginal Zone-Like B Cells.
Foo SS et al. Nat Microbiol 2017; 2 (11):1558-1570 Asian Zika virus strains target CD14+ blood monocytes and induce M2-skewed immunosuppression during pregnancy.
Hashwah H et al. Proc Natl Acad Sci U S A 2017; 114 (36):9701-9706 Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
Wang WF et al. Nat Commun 2017; 8 (1):363 HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.
Berggren O et al. PLoS One 2017; 12 (8):e0183946 Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype.
Luk F et al. Front Immunol 2017; 8:1042 Inflammatory Conditions Dictate the Effect of Mesenchymal Stem or Stromal Cells on B Cell Function.
Bruno TC et al. Cancer Immunol Res 2017; 5 (10):898-907 Antigen-Presenting Intratumoral B Cells Affect CD4+ TIL Phenotypes in Non-Small Cell Lung Cancer Patients.
Rechtien A et al. Cell Rep 2017; 20 (9):2251-2261 Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV.
Sielatycka K et al. Stem Cell Rev Rep 2017; 13 (6):774-780 Novel View on Umbilical Cord Blood and Maternal Peripheral Blood-an Evidence for an Increase in the Number of Circulating Stem Cells on Both Sides of the Fetal-Maternal Circulation Barrier.
Nagasawa M et al. Front Immunol 2017; 8:1047 Human CD5+ Innate Lymphoid Cells Are Functionally Immature and Their Development from CD34+ Progenitor Cells Is Regulated by Id2.
Ake JA et al. J Infect Dis 2017; 216 (9):1080-1090 Safety and Immunogenicity of PENNVAX-G DNA Prime Administered by Biojector 2000 or CELLECTRA Electroporation Device With Modified Vaccinia Ankara-CMDR Boost.
Mettananda S et al. Nat Commun 2017; 8 (1):424 Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.
Schwerd T et al. J Exp Med 2017; 214 (9):2547-2562 A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis.
Rai AK et al. Clin Exp Immunol 2017; 190 (3):340-350 Exonal switch down-regulates the expression of CD5 on blasts of acute T cell leukaemia.
Salio M et al. J Immunol 2017; 199 (8):2631-2638 Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells.
Cardoso V et al. Nature 2017; 549 (7671):277-281 Neuronal regulation of type 2 innate lymphoid cells via neuromedin U.
Klose CSN et al. Nature 2017; 549 (7671):282-286 The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation.
Snir O et al. JCI Insight 2017; 2 (17) Stereotyped antibody responses target posttranslationally modified gluten in celiac disease.
Meeuwsen JAL et al. J Am Heart Assoc 2017; 6 (9) High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease.
Kyoizumi S et al. J Immunol 2017; 199 (8):2777-2793 Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors.
Kaiser Y et al. Front Immunol 2017; 8:1130 Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in L?fgren's Syndrome and Non-L?fgren's Syndrome Sarcoidosis.
Jagannathan P et al. Sci Rep 2017; 7 (1):11487 Vδ2+ T cell response to malaria correlates with protection from infection but is attenuated with repeated exposure.
ManfrereC KCG et al. Oncotarget 2017; 8 (54):92183-92194 Profile of differentially expressed Toll-like receptor signaling genes in the natural killer cells of patients with S?zary syndrome.
Marcq E et al. Oncotarget 2017; 8 (52):89722-89735 Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients.
Reinisch A et al. Nat Protoc 2017; 12 (10):2169-2188 Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.
Bak RO et al. Elife 2017; 6 Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.
Choi YJ et al. Exp Mol Med 2017; 49 (9):e382 Impaired polyfunctionality of CD8+ T cells in severe sepsis patients with human cytomegalovirus reactivation.
Weiner J et al. Transplantation 2017; 101 (10):2449-2454 Long-term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation.
M?rklin M et al. Nat Commun 2017; 8 (1):755 NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.
Arthur Huang KY et al. Nat Commun 2017; 8 (1):762 Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children.
Ucar D et al. J Exp Med 2017; 214 (10):3123-3144 The chromatin accessibility signature of human immune aging stems from CD8+ T cells.
Abana CO et al. J Immunol 2017; 199 (9):3187-3201 Cytomegalovirus (CMV) Epitope-Specific CD4+ T Cells Are Inflated in HIV+ CMV+ Subjects.
Catalan-Dibene J et al. J Immunol 2017; 199 (9):3326-3335 Identification of IL-40, a Novel B Cell-Associated Cytokine.
Li J et al. J Immunol 2017; 199 (10):3504-3515 Aryl Hydrocarbon Receptor Activation Suppresses EBF1 and PAX5 and Impairs Human B Lymphopoiesis.
Tothova Z et al. Cell Stem Cell 2017; 21 (4):547-555.e8 Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia.
Jeong JH et al. Front Immunol 2017; 8:1260 CD14+ Cells with the Phenotype of Infiltrated Monocytes Consist of Distinct Populations Characterized by Anti-inflammatory as well as Pro-inflammatory Activity in Gouty Arthritis.
Espinosa V et al. Sci Immunol 2017; 2 (16) Type III interferon is a critical regulator of innate antifungal immunity.
Karampetsou MP et al. PLoS One 2017; 12 (10):e0186073 Expression patterns of signaling lymphocytic activation molecule family members in peripheral blood mononuclear cell subsets in patients with systemic lupus erythematosus.
Garz AK et al. Oncotarget 2017; 8 (65):108738-108759 Azacitidine combined with the selective FLT3 kinase inhibitor crenolanib disrupts stromal protection and inhibits expansion of residual leukemia-initiating cells in FLT3-ITD AML with concurrent epigenetic mutations.
Boyle MJ et al. Front Immunol 2017; 8:1329 The Development of Plasmodium falciparum-Specific IL10 CD4 T Cells and Protection from Malaria in Children in an Area of High Malaria Transmission.
Dahlin JS et al. Blood 2017; 130 (16):1785-1794 KIT signaling is dispensable for human mast cell progenitor development.
McFarlin BK et al. Front Physiol 2017; 8:786 Oral Supplementation with Baker's Yeast Beta Glucan Is Associated with Altered Monocytes, T Cells and Cytokines following a Bout of Strenuous Exercise.
Alroqi FJ et al. J Clin Immunol 2017; 37 (8):811-819 DOCK8 Deficiency Presenting as an IPEX-Like Disorder.
Smith AR et al. Blood Adv 2017; 1 (23):2083-2087 Cadherin 17 mutation associated with leaky severe combined immune deficiency is corrected by HSCT.
Herndler-Brandstetter D et al. Proc Natl Acad Sci U S A 2017; 114 (45):E9626-E9634 Humanized mouse model supports development, function, and tissue residency of human natural killer cells.
Keustermans G et al. PLoS One 2017; 12 (10):e0187068 Differential adipokine receptor expression on circulating leukocyte subsets in lean and obese children.
Duyen HTL et al. Sci Rep 2017; 7 (1):14224 Skin dendritic cell and T cell activation associated with dengue shock syndrome.
Speir M et al. Sci Rep 2017; 7 (1):14273 Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins.
Fumey W et al. Sci Rep 2017; 7 (1):14289 Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo.
Zhou Y et al. Front Cell Infect Microbiol 2017; 7:457 Application of ImmunoScore Model for the Differentiation between Active Tuberculosis and Latent Tuberculosis Infection as Well as Monitoring Anti-tuberculosis Therapy.
Rivera-Correa J et al. Nat Commun 2017; 8 (1):1282 Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria.
He Y et al. Front Immunol 2017; 8:1435 Interferon-α-Enhanced CD100/Plexin-B1/B2 Interactions Promote Natural Killer Cell Functions in Patients with Chronic Hepatitis C Virus Infection.
Arkatkar T et al. J Exp Med 2017; 214 (11):3207-3217 B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.
Duchartre Y et al. PLoS One 2017; 12 (11):e0187684 Effects of CD49d-targeted antisense-oligonucleotide on α4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies.
Pinder CL et al. J Immunol 2017; 199 (12):4180-4188 Isolation and Characterization of Antigen-Specific Plasmablasts Using a Novel Flow Cytometry-Based Ig Capture Assay.
Gladkikh AA et al. Cancer Med 2017; 6 (12):2984-2997 Comparison of the mRNA expression profile of B-cell receptor components in normal CD5-high B-lymphocytes and chronic lymphocytic leukemia: a key role of ZAP70.
Qin J et al. Biomed Res Int 2017; 2017:8431838 Increased Circulating Th17 but Decreased CD4+Foxp3+ Treg and CD19+CD1dhiCD5+ Breg Subsets in New-Onset Graves' Disease.
Marras F et al. J Virol 2017; 91 (23) Control of the HIV-1 DNA Reservoir Is Associated In Vivo and In Vitro with NKp46/NKp30 (CD335 CD337) Inducibility and Interferon Gamma Production by Transcriptionally Unique NK Cells.
Snijder B et al. Lancet Haematol 2017; 4 (12):e595-e606 Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study.
Basnett J et al. PLoS One 2017; 12 (11):e0188042 Regulation of the bone marrow microenvironment by G-CSF: Effects of G-CSF on acute lymphoblastic leukaemia.
Taurozzi AJ et al. PLoS One 2017; 12 (11):e0188228 Spontaneous development of Epstein-Barr Virus associated human lymphomas in a prostate cancer xenograft program.
Eggers EL et al. JCI Insight 2017; 2 (22) Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients.
Hu D et al. Nat Commun 2017; 8 (1):1600 Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis.
Santos RLA et al. Nat Commun 2017; 8 (1):1692 Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
Euteneuer F et al. Front Psychiatry 2017; 8:250 Peripheral Immune Alterations in Major Depression: The Role of Subtypes and Pathogenetic Characteristics.
Gomez-Tourino I et al. Nat Commun 2017; 8 (1):1792 T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes.
Paivandy A et al. Front Immunol 2017; 8:1645 Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells.
Strasser L et al. Sci Rep 2017; 7 (1):16638 Unbiased Quantitative Proteomics Reveals a Crucial Role of the Allergen Context for the Activation of Human Dendritic Cells.
Grifoni A et al. J Virol 2017; 91 (24) Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans.
Walker JA et al. Stem Cells Dev 2017; 26 (23):1715-1723 Humoral Immunity in Mice Transplanted with Hematopoietic Stem Cells Derived from Human Umbilical Cord Blood Recapitulates That of Human Infants.
Alc?ntara-Hern?ndez M et al. Immunity 2017; 47 (6):1037-1050.e6 High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.
Lee HJ et al. Oncotarget 2017; 8 (69):113345-113359 Expansion of tumor-infiltrating lymphocytes and their potential for application as adoptive cell transfer therapy in human breast cancer.
Urbansky A et al. Sci Rep 2017; 7 (1):17161 Rapid and effective enrichment of mononuclear cells from blood using acoustophoresis.
Pedros C et al. JCI Insight 2017; 2 (23) Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity.
Turaj AH et al. Cancer Cell 2017; 32 (6):777-791.e6 Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.
Sathe P et al. Int J Mol Sci 2017; 18 (12) Identification of Novel Human NK Cell Progenitor Subsets.
Soslow JH et al. Front Pharmacol 2017; 8:914 Increased Number of Circulating CD8/CD26 T Cells in the Blood of Duchenne Muscular Dystrophy Patients Is Associated with Augmented Binding of Adenosine Deaminase and Higher Muscular Strength Scores.
Cosma G et al. Front Immunol 2017; 8:1771 Identifying the Presence of Prostate Cancer in Individuals with PSA Levels <20?ng ml-1 Using Computational Data Extraction Analysis of High Dimensional Peripheral Blood Flow Cytometric Phenotyping Data.
Canter RJ et al. J Immunother Cancer 2017; 5 (1):98 Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial.
Sander J et al. Immunity 2017; 47 (6):1051-1066.e12 Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2.
Gavegnano C et al. PLoS Pathog 2017; 13 (12):e1006740 Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Panagoulias I et al. Front Immunol 2017; 8:1924 Ets-2 Acts As a Transcriptional Repressor of the Human Immunodeficiency Virus Type 1 through Binding to a Repressor-Activator Target Sequence of 5'-LTR.
Weinberg A et al. Front Immunol 2017; 8:2002 B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine.
B?zie S et al. Front Immunol 2017; 8:2014 Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/- Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice.
Anderson AE et al. Ann Rheum Dis 2016; 75 (2):466-73 IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis.
Yong KS et al. Cell Mol Immunol 2016; 13 (5):605-14 Human CD34(lo)CD133(lo) fetal liver cells support the expansion of human CD34(hi)CD133(hi) hematopoietic stem cells.
Duggal NA et al. Biogerontology 2016; 17 (1):229-39 Development of depressive symptoms post hip fracture is associated with altered immunosuppressive phenotype in regulatory T and B lymphocytes.
Saulep-Easton D et al. Leukemia 2016; 30 (1):163-72 The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells.
Huang X et al. Leukemia 2016; 30 (1):144-53 Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression.
Wright PB et al. Rheumatology (Oxford) 2016; 55 (1):120-32 Ankylosing spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation.
Lim TS et al. Oncoimmunology 2016; 5 (3):e1085146 PD-1 expression on dendritic cells suppresses CD8+ T cell function and antitumor immunity.
Bernardo D et al. Cell Mol Gastroenterol Hepatol 2016; 2 (1):22-39.e5 Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell?Recruitment to the Human Colon but Is Not Responsible?for?Differences Observed in Dendritic Cell?Subsets,?Phenotype, and Function Between the Proximal?and?Distal Colon.
Jindra PT et al. Biol Blood Marrow Transplant 2016; 22 (1):27-36 Analysis of a Genetic Polymorphism in the Costimulatory?Molecule TNFSF4 with Hematopoietic Stem?Cell?Transplant Outcomes.
Campi-Azevedo AC et al. Hum Vaccin Immunother 2016; 12 (2):491-502 Booster dose after 10 years is recommended following 17DD-YF primary vaccination.
Cook AM et al. Oncoimmunology 2016; 5 (3):e1066062 Dexamethasone co-medication in cancer patients undergoing chemotherapy causes substantial immunomodulatory effects with implications for chemo-immunotherapy strategies.
Yee CS et al. J Allergy Clin Immunol 2016; 137 (3):879-88.e2 Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association.
Marycz K et al. Stem Cells Int 2016; 2016:5756901 Endurance Exercise Mobilizes Developmentally Early Stem Cells into Peripheral Blood and Increases Their Number in Bone Marrow: Implications for Tissue Regeneration.
Venkatasubramanian S et al. Eur J Immunol 2016; 46 (2):464-79 Tissue factor expression by myeloid cells contributes to protective immune response against Mycobacterium tuberculosis infection.
Verron?se E et al. Oncoimmunology 2016; 5 (3):e1100791 Immune cell dysfunctions in breast cancer patients detected through whole blood multi-parametric flow cytometry assay.
Gavin KM et al. FASEB J 2016; 30 (3):1096-108 De novo generation of adipocytes from circulating progenitor cells in mouse and human adipose tissue.
Slingluff CL Jr et al. Cancer Immunol Immunother 2016; 65 (1):25-36 A randomized pilot trial testing the safety and immunologic effects of a MAGE-A3 protein plus AS15 immunostimulant administered into muscle or into dermal/subcutaneous sites.
Tosh KW et al. J Immunol 2016; 196 (1):345-56 The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion.
Kobayashi S et al. Eur J Immunol 2016; 46 (2):360-71 TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells.
Jabara HH et al. Nat Genet 2016; 48 (1):74-8 A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Chamberlain N et al. J Clin Invest 2016; 126 (1):282-7 Rituximab does not reset defective early B cell tolerance checkpoints.
Adamiak M et al. Leukemia 2016; 30 (4):919-28 Evidence that a lipolytic enzyme--hematopoietic-specific phospholipase C-β2--promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes.
Thome JJ et al. Nat Med 2016; 22 (1):72-7 Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues.
Nalivaiko K et al. Mol Ther 2016; 24 (2):298-305 A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells.
Henault J et al. Nat Immunol 2016; 17 (2):196-203 Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
Guo A et al. Oncotarget 2016; 7 (4):4598-610 Heightened BTK-dependent cell proliferation in unmutated chronic lymphocytic leukemia confers increased sensitivity to ibrutinib.
Williams LR et al. J Virol 2016; 90 (2):947-58 Induction of the Lytic Cycle Sensitizes Epstein-Barr Virus-Infected B Cells to NK Cell Killing That Is Counteracted by Virus-Mediated NK Cell Evasion Mechanisms in the Late Lytic Cycle.
Deng C et al. Diabetes Care 2016; 39 (3):434-40 Altered Peripheral B-Lymphocyte Subsets in Type 1 Diabetes and Latent Autoimmune Diabetes in Adults.
Kyoizumi S et al. Radiat Res 2016; 185 (1):69-76 Circulating Hematopoietic Stem and Progenitor Cells in Aging Atomic Bomb Survivors.
De Grove KC et al. PLoS One 2016; 11 (1):e0145961 Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung.
Lewis MJ et al. Arthritis Res Ther 2016; 18:5 Improved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1.
Joly-Battaglini A et al. F1000Res 2016; 5:38 Rituximab efficiently depletes B cells in lung tumors?and normal lung tissue.
Greco SH et al. J Leukoc Biol 2016; 100 (1):185-94 Mincle suppresses Toll-like receptor 4 activation.
Lang J et al. J Exp Med 2016; 213 (1):93-108 Receptor editing and genetic variability in human autoreactive B cells.
Nielsen CH et al. PLoS One 2016; 11 (1):e0146971 Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis.
Baglio SR et al. Proc Natl Acad Sci U S A 2016; 113 (5):E587-96 Sensing of latent EBV infection through exosomal transfer of 5'pppRNA.
Macal M et al. J Immunol 2016; 196 (4):1900-9 CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells.
Pearson C et al. Elife 2016; 5:e10066 ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
Frei AP et al. Nat Methods 2016; 13 (3):269-75 Highly multiplexed simultaneous detection of RNAs and proteins in single cells.
Guo XZ et al. Mol Ther Methods Clin Dev 2016; 3:15054 Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis.
Lin YC et al. Neurol Neuroimmunol Neuroinflamm 2016; 3 (1):e196 Patients with MS under daclizumab therapy mount normal immune responses to influenza vaccination.
Dahlin JS et al. Blood 2016; 127 (4):383-91 Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors.
Roan F et al. J Immunol 2016; 196 (5):2051-2062 CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.
Llibre A et al. J Immunol 2016; 196 (5):2085-94 LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation.
Parente-Ribes A et al. Haematologica 2016; 101 (2):e59-62 Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells.
Geherin SA et al. J Immunol 2016; 196 (6):2514-2525 IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require α4β1 Integrin To Migrate between the Peritoneum and Inflamed Skin.
Ludigs K et al. Nat Commun 2016; 7:10554 NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions.
Le Nours J et al. Nat Commun 2016; 7:10570 Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Fresnay S et al. J Transl Med 2016; 14:62 Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans.
Sullivan RT et al. Malar J 2016; 15:139 B cell sub-types following acute malaria and associations with clinical immunity.
Edvardsen K et al. J Transl Med 2016; 14:68 Analysis of cellular and humoral immune responses against cytomegalovirus in patients with autoimmune Addison's disease.
Wei?m?ller S et al. PLoS One 2016; 11 (3):e0149093 TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model.
Mattoo H et al. J Allergy Clin Immunol 2016; 138 (3):825-838 Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease.
Norstr?m MM et al. Oncotarget 2016; 7 (17):23581-93 Progression of benign prostatic hyperplasia is associated with pro-inflammatory mediators and chronic activation of prostate-infiltrating lymphocytes.
Serr I et al. Nat Commun 2016; 7:10991 Type 1 diabetes vaccine candidates promote human Foxp3(+)Treg induction in humanized mice.
Liou LB et al. PLoS One 2016; 11 (3):e0151669 Sialyltransferase and Neuraminidase Levels/Ratios and Sialic Acid Levels in Peripheral Blood B Cells Correlate with Measures of Disease Activity in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Pilot Study.
Hromadnikova I et al. PLoS One 2016; 11 (3):e0151535 Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B Cells and NKT Cells.
Coraglia A et al. J Immunol Res 2016; 2016:4951587 Common Variable Immunodeficiency and Circulating TFH.
Lee-Chang C et al. J Immunol 2016; 196 (8):3385-97 Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers.
Meffre E et al. JCI Insight 2016; 1 (3) Maturational characteristics of HIV-specific antibodies in viremic individuals.
Barsotti NS et al. PLoS One 2016; 11 (3):e0151761 IL-10-Producing Regulatory B Cells Are Decreased in Patients with Common Variable Immunodeficiency.
Leone DA et al. PLoS One 2016; 11 (3):e0151674 The Phenotypic Characterization of the Human Renal Mononuclear Phagocytes Reveal a Co-Ordinated Response to Injury.
Monticelli LA et al. Nat Immunol 2016; 17 (6):656-65 Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.
Jourdan M et al. Oncotarget 2016; 7 (19):28096-111 Differential effects of lenalidomide during plasma cell differentiation.
Tebbe B et al. PLoS One 2016; 11 (4):e0153170 Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19+CD24hiCD38hi Regulatory B-Lymphocytes.
du Plessis WJ et al. PLoS One 2016; 11 (4):e0152710 The Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis.
Fletcher HA et al. Nat Commun 2016; 7:11290 T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Garcia J et al. Sci Rep 2016; 6:24295 Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus.
Belov L et al. J Extracell Vesicles 2016; 5:25355 Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples.
Park JK et al. Arthritis Res Ther 2016; 18:91 HM71224, a novel Bruton's tyrosine kinase inhibitor, suppresses B cell and monocyte activation and ameliorates arthritis in a mouse model: a potential drug for rheumatoid arthritis.
Pugholm LH et al. J Immunol Res 2016; 2016:6391264 Phenotyping of Leukocytes and Leukocyte-Derived Extracellular Vesicles.
Zhang C et al. Immunity 2016; 44 (4):913-923 CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer.
Kajimura J et al. Mutat Res Genet Toxicol Environ Mutagen 2016; 802:59-65 Relationship between spontaneous γH2AX foci formation and progenitor functions in circulating hematopoietic stem and progenitor cells among atomic-bomb survivors.
Tossige-Gomes R et al. PLoS One 2016; 11 (4):e0153647 Lymphocyte Redox Imbalance and Reduced Proliferation after a Single Session of High Intensity Interval Exercise.
Rufener GA et al. Cancer Immunol Res 2016; 4 (6):509-19 Preserved Activity of CD20-Specific Chimeric Antigen Receptor-Expressing T Cells in the Presence of Rituximab.
Clement M et al. Front Immunol 2016; 7:158 Tertiary Lymphoid Organs in Takayasu Arteritis.
Loughland JR et al. Infect Immun 2016; 84 (5):1403-1412 Profoundly Reduced CD1c+ Myeloid Dendritic Cell HLA-DR and CD86 Expression and Increased Tumor Necrosis Factor Production in Experimental Human Blood-Stage Malaria Infection.
Lisenko K et al. Cancer Med 2016; 5 (7):1464-72 Flow cytometry-based characterization of underlying clonal B and plasma cells in patients with light chain amyloidosis.
Qualai J et al. PLoS One 2016; 11 (4):e0154253 Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential.
Rentas S et al. Nature 2016; 532 (7600):508-511 Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.
Jackson SW et al. J Exp Med 2016; 213 (5):733-50 B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.
Lee SC et al. Nat Med 2016; 22 (6):672-8 Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.
Pedros C et al. Nat Immunol 2016; 17 (7):825-33 A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.
Fromm PD et al. Oncoimmunology 2016; 5 (6):e1168555 CMRF-56(+) blood dendritic cells loaded with mRNA induce effective antigen-specific cytotoxic T-lymphocyte responses.
Stikvoort A et al. PLoS One 2016; 11 (5):e0154737 Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant?
Perdomo-Celis F et al. Clin Vaccine Immunol 2016; 23 (5):417-426 Viability and Functionality of Cryopreserved Peripheral Blood Mononuclear Cells in Pediatric Dengue.
Gross CC et al. Proc Natl Acad Sci U S A 2016; 113 (21):E2973-82 Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.
Cheeseman HM et al. PLoS One 2016; 11 (5):e0154656 Expression Profile of Human Fc Receptors in Mucosal Tissue: Implications for Antibody-Dependent Cellular Effector Functions Targeting HIV-1 Transmission.
Fletcher HA et al. BMC Med 2016; 14:76 Human newborn bacille Calmette-Gu?rin vaccination and risk of tuberculosis disease: a case-control study.
Dou DR et al. Nat Cell Biol 2016; 18 (6):595-606 Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Ma SD et al. PLoS Pathog 2016; 12 (5):e1005642 PD-1/CTLA-4 Blockade Inhibits Epstein-Barr Virus-Induced Lymphoma Growth in a Cord Blood Humanized-Mouse Model.
G?bel K et al. Nat Commun 2016; 7:11626 Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Pennington LF et al. Nat Commun 2016; 7:11610 Structural basis of omalizumab therapy and omalizumab-mediated IgE exchange.
Forcade E et al. Blood 2016; 127 (20):2489-97 Circulating T follicular helper cells with increased function during chronic graft-versus-host disease.
Tullett KM et al. JCI Insight 2016; 1 (7):e87102 Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell recognition.
Albertini MR et al. Cancer Immunol Immunother 2016; 65 (8):897-907 Phase I study to evaluate toxicity and feasibility of intratumoral injection of α-gal glycolipids in patients with advanced melanoma.
Park D et al. Histopathology 2016; 69 (3):516-21 Novel insights into the early histopathogenesis of immunodeficiency-associated Burkitt lymphoma: a case report of Burkitt microlymphoma arising within HIV lymphadenitis.
Reinisch A et al. Nat Med 2016; 22 (7):812-21 A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.
Schoenhals M et al. Cell Cycle 2016; 15 (14):1919-28 Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage.
Vaccari M et al. Nat Med 2016; 22 (7):762-70 Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
Lima J et al. BMC Pregnancy Childbirth 2016; 16 (1):139 Characterization of B cells in healthy pregnant women from late pregnancy to post-partum: a prospective observational study.
Kim JH et al. Sci Rep 2016; 6:27615 Natural killer cells regulate eosinophilic inflammation in chronic rhinosinusitis.
Lee KS et al. PLoS One 2016; 11 (6):e0156979 Local Immune Responses in Children and Adults with Allergic and Nonallergic Rhinitis.
Urbansky A et al. Micromachines (Basel) 2016; 7 (6) Affinity-Bead-Mediated Enrichment of CD8+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Acoustophoresis.
Magnani CF et al. Oncotarget 2016; 7 (32):51581-51597 Immunotherapy of acute leukemia by chimeric antigen receptor-modified lymphocytes using an improved Sleeping Beauty transposon platform.
Joosten SA et al. PLoS Pathog 2016; 12 (6):e1005687 Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment.
Schr?der M et al. PLoS One 2016; 11 (6):e0157387 CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits.
Menard LC et al. JCI Insight 2016; 1 (9):e87310 B cells from African American lupus patients exhibit an activated phenotype.
O'Connor KS et al. Genes Immun 2016; 17 (6):328-34 IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection.
Tschan-Plessl A et al. Transplant Direct 2016; 2 (7):e89 Human Cytomegalovirus Infection Enhances NK Cell Activity In Vitro.
Li S et al. Nat Med 2016; 22 (7):792-9 Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Dan JM et al. J Immunol 2016; 197 (3):983-93 A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.
Wittmann A et al. J Biol Chem 2016; 291 (34):17629-38 Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells.
Rundberg Nilsson A et al. PLoS One 2016; 11 (7):e0158369 Human and Murine Hematopoietic Stem Cell Aging Is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.
Zhang W et al. Oncotarget 2016; 7 (37):59098-59114 Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases.
Nagafuchi Y et al. Sci Rep 2016; 6:29338 Immunophenotyping of rheumatoid arthritis reveals a linkage between HLA-DRB1 genotype, CXCR4 expression on memory CD4(+) T cells, and disease activity.
Koreth J et al. Blood 2016; 128 (1):130-7 Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease.
Saito A et al. J Virol 2016; 90 (15):6918-6935 Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.
Lindestam Arlehamn CS et al. PLoS Pathog 2016; 12 (7):e1005760 A Quantitative Analysis of Complexity of Human Pathogen-Specific CD4 T Cell Responses in Healthy M. tuberculosis Infected South Africans.
Akiyama M et al. Arthritis Res Ther 2016; 18:167 Enhanced IgG4 production by follicular helper 2?T cells and the involvement of follicular helper 1?T cells in the pathogenesis of IgG4-related disease.
Paroni M et al. Clin Transl Gastroenterol 2016; 7 (7):e182 Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy.
Jonas BA et al. PLoS One 2016; 11 (7):e0159189 Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.
Schickel JN et al. Sci Immunol 2016; 1 (1) PTPN22 inhibition resets defective human central B cell tolerance.
Neumann L et al. J Immunol 2016; 197 (5):1801-8 Mucosal Inducible NO Synthase-Producing IgA+ Plasma Cells in Helicobacter pylori-Infected Patients.
Muir R et al. PLoS Pathog 2016; 12 (7):e1005777 Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
Jacoby E et al. Nat Commun 2016; 7:12320 CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.
du Plessis WJ et al. J Inflamm (Lond) 2016; 13:23 Phenotypic analysis of peripheral B cell populations during Mycobacterium tuberculosis infection and disease.
Sullivan KD et al. Elife 2016; 5 Trisomy 21 consistently activates the interferon response.
Jasek M et al. Tumour Biol 2016; 37 (10):13617-13626 Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia.
Comte D et al. Proc Natl Acad Sci U S A 2016; 113 (33):9321-6 Engagement of SLAMF3 enhances CD4+ T-cell sensitivity to IL-2 and favors regulatory T-cell polarization in systemic lupus erythematosus.
Cheng WC et al. Eur J Immunol 2016; 46 (9):2211-21 Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses.
Demers KR et al. PLoS Pathog 2016; 12 (8):e1005805 Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.
Cartellieri M et al. Blood Cancer J 2016; 6 (8):e458 Switching CAR T cells on and off: a novel modular platform for retargeting of T cells to AML blasts.
Zhong H et al. Hepat Mon 2016; 16 (9):e36068 Interleukin-7 in Patients With Chronic Hepatitis B May Have Effect on T Follicular Helper Cells and Specific Cellular Immunity.
van der Aa E et al. PLoS One 2016; 11 (8):e0161235 The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.
Ten Hacken E et al. J Immunol 2016; 197 (6):2522-31 Functional Differences between IgM and IgD Signaling in Chronic Lymphocytic Leukemia.
Lizotte PH et al. Sci Rep 2016; 6:31745 Fine needle aspirate flow cytometric phenotyping characterizes immunosuppressive nature of the mesothelioma microenvironment.
Loh L et al. Proc Natl Acad Sci U S A 2016; 113 (36):10133-8 Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation.
Henry EK et al. J Exp Med 2016; 213 (9):1663-73 Carbonic anhydrase enzymes regulate mast cell-mediated inflammation.
Huynh L et al. Sci Rep 2016; 6:31959 Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages.
Toro JF et al. PLoS One 2016; 11 (8):e0161795 Total and Envelope Protein-Specific Antibody-Secreting Cell Response in Pediatric Dengue Is Highly Modulated by Age and Subsequent Infections.
Beschel LM et al. Oncotarget 2016; 7 (40):65902-65915 T cell abundance in blood predicts acute organ toxicity in chemoradiotherapy for head and neck cancer.
Kurupati R et al. Oncotarget 2016; 7 (39):62898-62911 Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood.
Kleinsteuber K et al. Cytometry A 2016; 89 (10):903-913 Standardization and quality control for high-dimensional mass cytometry studies of human samples.
Chaves YO et al. Malar J 2016; 15 (1):445 Immune response pattern in recurrent Plasmodium vivax malaria.
Tomita Y et al. Oncoimmunology 2016; 5 (11):e1219008 The interplay of epigenetic therapy and immunity in locally recurrent or metastatic estrogen receptor-positive breast cancer: Correlative analysis of ENCORE 301, a randomized, placebo-controlled phase II trial of exemestane with or without entinostat.
Fontana MF et al. PLoS One 2016; 11 (9):e0162132 A Novel Model of Asymptomatic Plasmodium Parasitemia That Recapitulates Elements of the Human Immune Response to Chronic Infection.
Sch?tz C et al. Oncotarget 2016; 7 (42):68503-68512 Antigen-specific T cell Redirectors: a nanoparticle based approach for redirecting T cells.
Malkiel S et al. Arthritis Rheumatol 2016; 68 (9):2210-20 Checkpoints for Autoreactive B Cells in the Peripheral Blood of Lupus Patients Assessed by Flow Cytometry.
Cooke RE et al. J Transl Med 2016; 14:259 Spontaneous onset and transplant models of the Vk*MYC mouse show immunological sequelae comparable to human multiple myeloma.
Lu XJ et al. Nat Commun 2016; 7:12719 LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells.
Price AA et al. Proc Natl Acad Sci U S A 2016; 113 (38):10678-83 Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotype.
Lizotte PH et al. JCI Insight 2016; 1 (14):e89014 Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes.
Lai J et al. Blood 2016; 128 (10):1396-407 Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificities.
Prabhu SB et al. PLoS One 2016; 11 (9):e0162242 Comparison of Human Neonatal and Adult Blood Leukocyte Subset Composition Phenotypes.
Williams GS et al. Oncotarget 2016; 7 (42):68278-68291 Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.
Wahid R et al. Clin Immunol 2016; 173:87-95 Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a.
Kalams SA et al. Eur J Contracept Reprod Health Care 2016; 21 (6):436-442 Neither vaginal nor buccal administration of 800?μg misoprostol alters mucosal and systemic immune activation or the cervicovaginal microbiome: a pilot study.
Guo H et al. J Exp Med 2016; 213 (10):2187-207 Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.
Andrews FH et al. Cell Rep 2016; 16 (12):3195-3207 Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.
Colluru VT et al. Oncotarget 2016; 7 (42):67901-67918 B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines.
Lake JE et al. HIV Clin Trials 2016; 17 (6):225-232 Telmisartan increases vascular reparative capacity in older HIV-infected adults: a pilot study.
Reinius B et al. Nat Genet 2016; 48 (11):1430-1435 Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA-seq.
Townsend CL et al. Front Immunol 2016; 7:388 Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions.
Su LF et al. Proc Natl Acad Sci U S A 2016; 113 (41):E6192-E6198 Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood.
Ho TC et al. Blood 2016; 128 (13):1671-8 Evolution of acute myelogenous leukemia stem cell properties after treatment and progression.
Kinslow JD et al. Arthritis Rheumatol 2016; 68 (10):2372-83 Elevated IgA Plasmablast Levels in Subjects at Risk of Developing Rheumatoid Arthritis.
Garcia J et al. Stem Cells Int 2016; 2016:6969726 Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat.
Albanese M et al. Proc Natl Acad Sci U S A 2016; 113 (42):E6467-E6475 Epstein-Barr virus microRNAs reduce immune surveillance by virus-specific CD8+ T cells.
Cantaert T et al. J Clin Invest 2016; 126 (11):4289-4302 Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
Serr I et al. Proc Natl Acad Sci U S A 2016; 113 (43):E6659-E6668 miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity.
Su KY et al. J Immunol 2016; 197 (10):4163-4176 Efficient Culture of Human Naive and Memory B Cells for Use as APCs.
Chong SZ et al. J Exp Med 2016; 213 (11):2293-2314 CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
Massaad MJ et al. J Clin Invest 2016; 126 (11):4219-4236 Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.
Ferreira-Teixeira M et al. BMC Med 2016; 14 (1):163 Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells.
Cuff AO et al. J Immunol 2016; 197 (11):4283-4291 Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation.
Yiwen Z et al. Oncotarget 2016; 7 (47):77732-77748 Efficient generation of antigen-specific CTLs by the BAFF-activated human B Lymphocytes as APCs: a novel approach for immunotherapy.
Carroll VA et al. Proc Natl Acad Sci U S A 2016; 113 (46):13168-13173 Expression of HIV-1 matrix protein p17 and association with B-cell lymphoma in HIV-1 transgenic mice.
Mackroth MS et al. PLoS Pathog 2016; 12 (11):e1005909 Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function.
Dam EM et al. Clin Immunol 2016; 173:171-180 The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.
Dendrou CA et al. Sci Transl Med 2016; 8 (363):363ra149 Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Seibert E et al. BMC Cardiovasc Disord 2016; 16 (1):210 Association between autonomic nervous dysfunction and cellular inflammation in end-stage renal disease.
Dever DP et al. Nature 2016; 539 (7629):384-389 CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells.
DiGiusto DL et al. Mol Ther Methods Clin Dev 2016; 3:16067 Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells.
Sairafi D et al. J Immunol Res 2016; 2016:5601204 Donor Cell Composition and Reactivity Predict Risk of Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.
Sherbenou DW et al. J Clin Invest 2016; 126 (12):4640-4653 Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.
Boisvert M et al. J Immunol 2016; 197 (12):4848-4858 Novel E2 Glycoprotein Tetramer Detects Hepatitis C Virus-Specific Memory B Cells.
Tarunina M et al. Stem Cells Dev 2016; 25 (22):1709-1720 A Novel High-Throughput Screening Platform Reveals an Optimized Cytokine Formulation for Human Hematopoietic Progenitor Cell Expansion.
Yeung YA et al. Nat Commun 2016; 7:13376 Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Kim L et al. Sci Rep 2016; 6:37295 Systemic and mucosal immune responses following oral adenoviral delivery of influenza vaccine to the human intestine by radio controlled capsule.
Skauli N et al. Genes (Basel) 2016; 7 (12) Novel PIGT Variant in Two Brothers: Expansion of the Multiple Congenital Anomalies-Hypotonia Seizures Syndrome 3 Phenotype.
Tomi? A et al. PLoS Pathog 2016; 12 (12):e1006015 Activation of Innate and Adaptive Immunity by a Recombinant Human Cytomegalovirus Strain Expressing an NKG2D Ligand.
Bar-Ephraim YE et al. PLoS One 2016; 11 (12):e0167555 A Reproducible Method for Isolation and In Vitro Culture of Functional Human Lymphoid Stromal Cells from Tonsils.
Joshua V et al. Arthritis Res Ther 2016; 18 (1):284 Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells.
Cerny D et al. J Allergy Clin Immunol 2016; 138 (6):1709-1712.e11 Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence.
Kelly A et al. J Interferon Cytokine Res 2016; 36 (12):671-680 Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway.
Martin VG et al. Front Immunol 2016; 7:546 Transitional B Cells in Early Human B Cell Development - Time to Revisit the Paradigm?
Seay HR et al. JCI Insight 2016; 1 (20):e88242 Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes.
Lubaki NM et al. PLoS Pathog 2016; 12 (12):e1006031 The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses.
Tzeng SJ et al. J Vis Exp 2016; (118) The Isolation, Differentiation, and Quantification of Human Antibody-secreting B Cells from Blood: ELISpot as a Functional Readout of Humoral Immunity.
Bergerson RJ et al. Blood Adv 2016; 1 (3):208-218 Fewer Circulating Natural Killer Cells 28 Days After Double Cord Blood Transplantation Predicts Inferior Survival and IL-15 Response.
Kinstrie R et al. Blood Adv 2016; 1 (3):160-169 Heterogeneous leukemia stem cells in myeloid blast phase chronic myeloid leukemia.
Wu GC et al. Nat Commun 2016; 7:13838 Temporal stability and molecular persistence of the bone marrow plasma cell antibody repertoire.
Llibre A et al. F1000Res 2016; 5:2929 Expression of lectin-like transcript-1 in human tissues.
Balandr?n JC et al. Front Immunol 2016; 7:666 Pro-inflammatory-Related Loss of CXCL12 Niche Promotes Acute Lymphoblastic Leukemic Progression at the Expense of Normal Lymphopoiesis.
Jiang Z et al. Front Immunol 2016; 7:690 Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma.
Raine T et al. Gut 2015; 64 (2):250-9 Generation of primary human intestinal T cell transcriptomes reveals differential expression at genetic risk loci for immune-mediated disease.
Della-Torre E et al. Ann Rheum Dis 2015; 74 (12):2236-43 B-cell depletion attenuates serological biomarkers of fibrosis and myofibroblast activation in IgG4-related disease.
Platzer B et al. Mucosal Immunol 2015; 8 (3):516-32 Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites.
Doores KJ et al. J Virol 2015; 89 (2):1105-18 Two classes of broadly neutralizing antibodies within a single lineage directed to the high-mannose patch of HIV envelope.
Hoff P et al. Cell Mol Immunol 2015; 12 (4):483-92 Effects of 60-day bed rest with and without exercise on cellular and humoral immunological parameters.
Williams DW et al. J Leukoc Biol 2015; 97 (2):401-12 JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV-infected individuals.
Tungatt K et al. J Immunol 2015; 194 (1):463-74 Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs.
Nunes-Caba?o H et al. J Virol 2015; 89 (4):2201-8 Thymic HIV-2 infection uncovers posttranscriptional control of viral replication in human thymocytes.
Damuzzo V et al. Cytometry B Clin Cytom 2015; 88 (2):77-91 Complexity and challenges in defining myeloid-derived suppressor cells.
Brestoff JR et al. Nature 2015; 519 (7542):242-6 Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.
Van Eyck L Jr et al. J Allergy Clin Immunol 2015; 135 (1):283-7.e5 Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.
Katawa G et al. PLoS Negl Trop Dis 2015; 9 (1):e3414 Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.
Schinnerling K et al. Infect Immun 2015; 83 (2):482-91 Role of dendritic cells in the pathogenesis of Whipple's disease.
Otomo T et al. J Cell Biol 2015; 208 (2):171-80 Mannose 6 phosphorylation of lysosomal enzymes controls B cell functions.
Spencer DH et al. Leukemia 2015; 29 (6):1279-89 Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.
Scheuplein VA et al. J Virol 2015; 89 (7):3859-69 High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus.
Botta Gordon-Smith S et al. Arthritis Rheumatol 2015; 67 (2):545-54 Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis.
Velazquez VM et al. Hepatology 2015; 61 (3):843-56 Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.
Poposki JA et al. Clin Exp Allergy 2015; 45 (2):384-93 Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis.
Boyle MJ et al. J Infect Dis 2015; 212 (3):416-25 Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations.
Lewis MJ et al. Am J Hum Genet 2015; 96 (2):221-34 UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.
Fischbach H et al. Nat Commun 2015; 6:6199 Ultrasensitive quantification of TAP-dependent antigen compartmentalization in scarce primary immune cell subsets.
Okamura T et al. Nat Commun 2015; 6:6329 TGF-β3-expressing CD4+CD25(-)LAG3+ regulatory T cells control humoral immune responses.
Hoek KL et al. PLoS One 2015; 10 (2):e0118528 A cell-based systems biology assessment of human blood to monitor immune responses after influenza vaccination.
Simchoni N et al. J Immunol 2015; 194 (7):3035-44 TLR7- and TLR9-responsive human B cells share phenotypic and genetic characteristics.
Breton G et al. J Exp Med 2015; 212 (3):401-13 Circulating precursors of human CD1c+ and CD141+ dendritic cells.
Lee J et al. J Exp Med 2015; 212 (3):385-99 Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow.
Cuthbert RJ et al. PLoS One 2015; 10 (3):e0117855 Examining the feasibility of clinical grade CD271+ enrichment of mesenchymal stromal cells for bone regeneration.
Garcia-Carmona Y et al. Blood 2015; 125 (11):1749-58 Differential induction of plasma cells by isoforms of human TACI.
Ohnuma K et al. J Immunol 2015; 194 (8):3697-712 Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.
Schilbach K et al. Oncoimmunology 2015; 4 (7):e1014760 Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation.
Misra R et al. Hum Immunol 2015; 76 (5):329-338 Preterm cord blood CD4? T cells exhibit increased IL-6 production in chorioamnionitis and decreased CD4? T cells in bronchopulmonary dysplasia.
Hong M et al. Nat Commun 2015; 6:6588 Trained immunity in newborn infants of HBV-infected mothers.
McCracken MN et al. J Clin Invest 2015; 125 (5):1815-26 Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.
Hatzi K et al. J Exp Med 2015; 212 (4):539-53 BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms.
Lin YC et al. Ann Clin Transl Neurol 2015; 2 (5):445-55 Daclizumab reverses intrathecal immune cell abnormalities in multiple sclerosis.
Wojno ED et al. Mucosal Immunol 2015; 8 (6):1313-23 The prostaglandin D? receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung.
Weinberg A et al. PLoS One 2015; 10 (4):e0122431 Determinants of vaccine immunogenicity in HIV-infected pregnant women: analysis of B and T cell responses to pandemic H1N1 monovalent vaccine.
Aybar LT et al. Clin Exp Immunol 2015; 180 (2):178-88 Reduced CD5(+) CD24(hi) CD38(hi) and interleukin-10(+) regulatory B cells in active anti-neutrophil cytoplasmic autoantibody-associated vasculitis permit increased circulating autoantibodies.
Gey A et al. Clin Exp Immunol 2015; 180 (2):280-8 Granulocytic myeloid-derived suppressor cells inversely correlate with plasma arginine and overall survival in critically ill patients.
Wahid R et al. Mucosal Immunol 2015; 8 (6):1349-59 Immunization with Ty21a live oral typhoid vaccine elicits crossreactive multifunctional CD8+ T-cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A, and S. Paratyphi B in humans.
Chimen M et al. Nat Med 2015; 21 (5):467-475 Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.
Pertovaara M et al. Clin Exp Immunol 2015; 181 (1):29-38 STAT-5 is activated constitutively in T cells, B cells and monocytes from patients with primary Sj?gren's syndrome.
Berent-Maoz B et al. PLoS One 2015; 10 (5):e0125414 The expansion of thymopoiesis in neonatal mice is dependent on expression of high mobility group a 2 protein (Hmga2).
Li XX et al. Infect Dis Poverty 2015; 4:20 Profiling B and T cell immune responses to co-infection of Mycobacterium tuberculosis and hookworm in humans.
Mirza RE et al. J Pathol 2015; 236 (4):433-44 Macrophage PPARγ and impaired wound healing in type 2 diabetes.
Schinke C et al. Blood 2015; 125 (20):3144-52 IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.
Crompot E et al. PLoS One 2015; 10 (5):e0127209 Avoiding false positive antigen detection by flow cytometry on blood cell derived microparticles: the importance of an appropriate negative control.
Weiskopf D et al. J Infect Dis 2015; 212 (11):1743-51 Human CD8+ T-Cell Responses Against the 4 Dengue Virus Serotypes Are Associated With Distinct Patterns of Protein Targets.
Elong Ngono A et al. J Immunol Res 2015; 2015:673503 Decreased Frequency of Circulating Myelin Oligodendrocyte Glycoprotein B Lymphocytes in Patients with Relapsing-Remitting Multiple Sclerosis.
Zuber J et al. Am J Transplant 2015; 15 (10):2691-703 Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD.
Sullivan RT et al. PLoS Pathog 2015; 11 (5):e1004894 FCRL5 Delineates Functionally Impaired Memory B Cells Associated with Plasmodium falciparum Exposure.
Samsonraj RM et al. Stem Cells 2015; 33 (6):1878-91 Establishing criteria for human mesenchymal stem cell potency.
McArthur MA et al. PLoS Pathog 2015; 11 (5):e1004914 Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
Yousef S et al. Hum Vaccin Immunother 2015; 11 (7):1606-11 CD229 is expressed on the surface of plasma cells carrying an aberrant phenotype and chemotherapy-resistant precursor cells in multiple myeloma.
Zhu D et al. Nat Med 2015; 21 (6):572-80 The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.
Yoshida Y et al. Arthritis Rheumatol 2015; 67 (6):1481-90 Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.
Salvatore G et al. J Lipid Res 2015; 56 (6):1110-22 Human monocyte-derived dendritic cells turn into foamy dendritic cells with IL-17A.
Boisson B et al. J Exp Med 2015; 212 (6):939-51 Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
Pusic I et al. Biol Blood Marrow Transplant 2015; 21 (10):1761-9 Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome.
Koreth J et al. Biol Blood Marrow Transplant 2015; 21 (11):1907-13 A Bortezomib-Based Regimen Offers Promising Survival and Graft-versus-Host Disease Prophylaxis in Myeloablative HLA-Mismatched and Unrelated Donor Transplantation: A Phase II Trial.
Rasmussen TK et al. Arthritis Res Ther 2015; 17:154 Overexpression of microRNA-155 increases IL-21 mediated STAT3 signaling and IL-21 production in systemic lupus erythematosus.
Rancan C et al. PLoS Pathog 2015; 11 (6):e1004906 Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells.
Chiappini N et al. PLoS One 2015; 10 (6):e0129879 Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro.
Perriard G et al. J Neuroinflammation 2015; 12:119 Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Kuebler PJ et al. Proc Natl Acad Sci U S A 2015; 112 (27):8379-84 Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial.
Boer MC et al. Clin Vaccine Immunol 2015; 22 (7):778-88 Mycobacterium bovis BCG Vaccination Induces Divergent Proinflammatory or Regulatory T Cell Responses in Adults.
Vaeth M et al. J Immunol 2015; 195 (3):1202-17 Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells.
Ruiter B et al. Clin Exp Allergy 2015; 45 (7):1214-25 Vitamins A and D have antagonistic effects on expression of effector cytokines and gut-homing integrin in human innate lymphoid cells.
Raval GU et al. Retrovirology 2015; 12:59 Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL.
Bekele Y et al. Medicine (Baltimore) 2015; 94 (27):e1125 Impaired Phenotype and Function of T Follicular Helper Cells in HIV-1-Infected Children Receiving ART.
Halliley JL et al. Immunity 2015; 43 (1):132-45 Long-Lived Plasma Cells Are Contained within the CD19(-)CD38(hi)CD138(+) Subset in Human Bone Marrow.
Fujii H et al. PLoS One 2015; 10 (7):e0133216 Humanized Chronic Graft-versus-Host Disease in NOD-SCID il2rγ-/- (NSG) Mice with G-CSF-Mobilized Peripheral Blood Mononuclear Cells following Cyclophosphamide and Total Body Irradiation.
Bodogai M et al. Cancer Res 2015; 75 (17):3456-65 Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells.
Trinschek B et al. Int J Mol Sci 2015; 16 (7):16330-46 Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.
Jones N et al. Clin Exp Immunol 2015; 182 (1):69-80 Bioenergetic analysis of human peripheral blood mononuclear cells.
Mende N et al. J Exp Med 2015; 212 (8):1171-83 CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo.
Fischer U et al. Nat Genet 2015; 47 (9):1020-1029 Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options.
Olesen R et al. J Virol 2015; 89 (20):10176-89 Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat.
Chukwuma VU et al. PLoS One 2015; 10 (7):e0133509 Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein.
Dolton G et al. Immunology 2015; 146 (1):11-22 More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers.
Teirlinck AC et al. Infect Immun 2015; 83 (9):3732-9 Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression.
Chen X et al. PLoS Negl Trop Dis 2015; 9 (8):e0004015 Distribution of Peripheral Memory T Follicular Helper Cells in Patients with Schistosomiasis Japonica.
Trend S et al. PLoS One 2015; 10 (8):e0135580 Leukocyte Populations in Human Preterm and Term Breast Milk Identified by Multicolour Flow Cytometry.
Muthumani K et al. Sci Transl Med 2015; 7 (301):301ra132 A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates.
Quast I et al. Neurol Neuroimmunol Neuroinflamm 2015; 2 (5):e148 Deregulated Fcγ receptor expression in patients with CIDP.
Corkum CP et al. BMC Immunol 2015; 16:48 Immune cell subsets and their gene expression profiles from human PBMC isolated by Vacutainer Cell Preparation Tube (CPT?) and standard density gradient.
Roskin KM et al. Sci Transl Med 2015; 7 (302):302ra135 IgH sequences in common variable immune deficiency reveal altered B cell development and selection.
Mikosik A et al. PLoS One 2015; 10 (8):e0136615 Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.
Wostradowski T et al. Clin Exp Immunol 2015; 182 (2):162-72 Effect of interferon-β1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients.
Chambers ES et al. J Allergy Clin Immunol 2015; 136 (3):628-637.e4 Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-γ(high) immunophenotypes: Potential benefits of calcitriol.
Catelas I et al. Clin Orthop Relat Res 2015; 473 (12):3903-14 Do patients with a failed metal-on-metal hip implant with a pseudotumor present differences in their peripheral blood lymphocyte subpopulations?
Matsui K et al. PLoS One 2015; 10 (9):e0137195 Circulating CXCR5?CD4? T Follicular-Like Helper Cell and Memory B Cell Responses to Human Papillomavirus Vaccines.
Gregorovic G et al. J Virol 2015; 89 (22):11711-4 Epstein-Barr Viruses (EBVs) Deficient in EBV-Encoded RNAs Have Higher Levels of Latent Membrane Protein 2 RNA Expression in Lymphoblastoid Cell Lines and Efficiently Establish Persistent Infections in Humanized Mice.
Alshevskaya AA et al. Mediators Inflamm 2015; 2015:948393 Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis.
Tian YF et al. Biomaterials 2015; 73:110-9 Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells.
Doisne JM et al. J Immunol 2015; 195 (8):3937-45 Composition, Development, and Function of Uterine Innate Lymphoid Cells.
Pala F et al. J Clin Invest 2015; 125 (10):3941-51 Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.
Booth JS et al. Front Immunol 2015; 6:466 Mucosal-Associated Invariant T Cells in the Human Gastric Mucosa and Blood: Role in Helicobacter pylori Infection.
Kolhatkar NS et al. J Exp Med 2015; 212 (10):1663-77 Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome.
Basha S et al. Clin Exp Immunol 2015; 182 (3):314-22 Poor memory B cell generation contributes to non-protective responses to DTaP vaccine antigens in otitis-prone children.
Uy GL et al. Leuk Res 2015; 39 (12):1437-42 Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia.
Ryotokuji K et al. Laser Ther 2015; 24 (3):179-88 Effect of Stress-Free Therapy on immune system: Induction of Interleukin 10 expression in lymphocytes through activation of CD19(+) CD24(hi) CD38(hi) regulatory B Cells.
Spel L et al. Oncotarget 2015; 6 (34):35770-81 Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma.
Tzeng SJ et al. J Biomed Sci 2015; 22:87 FcγRIIB mediates antigen-independent inhibition on human B lymphocytes through Btk and p38 MAPK.
Tsidulko AY et al. Oncotarget 2015; 6 (41):43529-39 Proteoglycan expression correlates with the phenotype of malignant and non-malignant EBV-positive B-cell lines.
Miles B et al. Nat Commun 2015; 6:8608 Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection.
Lakhal-Naouar I et al. PLoS Negl Trop Dis 2015; 9 (10):e0004178 The Immunology of a Healing Response in Cutaneous Leishmaniasis Treated with Localized Heat or Systemic Antimonial Therapy.
Sohlberg E et al. Oncotarget 2015; 6 (33):34178-90 Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome.
Liu X et al. Onco Targets Ther 2015; 8:3095-104 Potential therapeutic strategy for gastric cancer peritoneal metastasis by NKG2D ligands-specific T cells.
Kim KW et al. Stem Cell Res Ther 2015; 6:202 Optimization of adipose tissue-derived mesenchymal stem cells by rapamycin in a murine model of acute graft-versus-host disease.
Colineau L et al. PLoS One 2015; 10 (10):e0140978 HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation.
Duan Z et al. Oncotarget 2015; 6 (42):44239-53 Phenotype and function of CXCR5+CD45RA-CD4+ T cells were altered in HBV-related hepatocellular carcinoma and elevated serum CXCL13 predicted better prognosis.
Macauley MS et al. J Biol Chem 2015; 290 (50):30066-77 Unmasking of CD22 Co-receptor on Germinal Center B-cells Occurs by Alternative Mechanisms in Mouse and Man.
Dubois E et al. Neurol Neuroimmunol Neuroinflamm 2015; 2 (6):e177 Low frequencies of central memory CD4 T cells in progressive multifocal leukoencephalopathy.
Dutmer CM et al. J Clin Immunol 2015; 35 (8):754-60 Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection.
Moore JK et al. Cytotherapy 2015; 17 (11):1604-16 Phenotypic and functional characterization of macrophages with therapeutic potential generated from human cirrhotic monocytes in a cohort study.
Qamar N et al. Clin Exp Allergy 2015; 45 (11):1663-72 Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells.
Arriaga-Pizano L et al. Arch Med Res 2015; 46 (8):651-8 Differential Immune Profiles in Two Pandemic Influenza A(H1N1)pdm09 Virus Waves at Pandemic Epicenter.
Gunther S et al. Front Immunol 2015; 6:556 Correlation of Hsp70 Serum Levels with Gross Tumor Volume and Composition of Lymphocyte Subpopulations in Patients with Squamous Cell and Adeno Non-Small Cell Lung Cancer.
Cubas R et al. J Immunol 2015; 195 (12):5625-36 Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.
Stockklausner C et al. Aging (Albany NY) 2015; 7 (11):911-27 A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition.
Wang J et al. Nat Biotechnol 2015; 33 (12):1256-1263 Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.
Omilusik KD et al. J Exp Med 2015; 212 (12):2027-39 Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection.
Dunmire SK et al. PLoS Pathog 2015; 11 (12):e1005286 The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events.
Andrews SF et al. Sci Transl Med 2015; 7 (316):316ra192 Immune history profoundly affects broadly protective B cell responses to influenza.
Yamagishi M et al. Sci Rep 2015; 5:17868 Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma.
Westman J et al. PLoS Pathog 2015; 11 (12):e1005319 Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo.
Reyes-Avil?s E et al. PLoS One 2015; 10 (12):e0144629 Presence of Rheumatoid Factor during Chronic HCV Infection Is Associated with Expansion of Mature Activated Memory B-Cells that Are Hypo-Responsive to B-Cell Receptor Stimulation and Persist during the Early Stage of IFN Free Therapy.
Yin J et al. Proc Natl Acad Sci U S A 2015; 112 (52):15988-93 Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity.
Drummond RA et al. PLoS Pathog 2015; 11 (12):e1005293 CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.
Bigler MB et al. PLoS One 2015; 10 (12):e0145635 Stress-Induced In Vivo Recruitment of Human Cytotoxic Natural Killer Cells Favors Subsets with Distinct Receptor Profiles and Associates with Increased Epinephrine Levels.
Lee SJ et al. BMC Cancer 2015; 15:1011 Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain.
Nowak WN et al. J Diabetes Investig 2014; 5 (1):99-107 Number of circulating pro-angiogenic cells, growth factor and anti-oxidative gene profiles might be altered in type 2 diabetes with and without diabetic foot syndrome.
Beliakova-Bethell N et al. Cytometry A 2014; 85 (1):94-104 The effect of cell subset isolation method on gene expression in leukocytes.
Lozza L et al. Eur J Immunol 2014; 44 (1):80-92 Crosstalk between human DC subsets promotes antibacterial activity and CD8+ T-cell stimulation in response to bacille Calmette-Gu?rin.
Krishnan S et al. J Infect Dis 2014; 209 (6):931-9 Evidence for innate immune system activation in HIV type 1-infected elite controllers.
Compeer EB et al. J Biol Chem 2014; 289 (1):520-8 Tubulation of endosomal structures in human dendritic cells by Toll-like receptor ligation and lymphocyte contact accompanies antigen cross-presentation.
Trifonova RT et al. Am J Reprod Immunol 2014; 71 (3):252-64 Distribution of immune cells in the human cervix and implications for HIV transmission.
Chen Q et al. Proc Natl Acad Sci U S A 2014; 111 (4):1479-84 Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.
Beckwith KA et al. Leukemia 2014; 28 (7):1501-10 The CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model.
Sereti I et al. PLoS Pathog 2014; 10 (1):e1003890 Decreases in colonic and systemic inflammation in chronic HIV infection after IL-7 administration.
Ramon S et al. Eur J Immunol 2014; 44 (2):357-69 Lipoxin A? modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism.
Schweingruber N et al. Acta Neuropathol 2014; 127 (5):713-29 Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses.
Mavropoulos A et al. J Immunol Res 2014; 2014:671431 Flow cytometric detection of p38 MAPK phosphorylation and intracellular cytokine expression in peripheral blood subpopulations from patients with autoimmune rheumatic diseases.
Huang J et al. PLoS One 2014; 9 (2):e88205 An AAV vector-mediated gene delivery approach facilitates reconstitution of functional human CD8+ T cells in mice.
Itoua Ma?ga R et al. Biomed Res Int 2014; 2014:536482 Flow cytometry assessment of in vitro generated CD138+ human plasma cells.
Mirza RE et al. Diabetes 2014; 63 (3):1103-14 Sustained inflammasome activity in macrophages impairs wound healing in type 2 diabetic humans and mice.
Yamahara K et al. PLoS One 2014; 9 (2):e88319 Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells.
H?nniger K et al. PLoS Comput Biol 2014; 10 (2):e1003479 A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood.
Chognard G et al. PLoS One 2014; 9 (2):e89092 The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.
Greer AM et al. J Clin Invest 2014; 124 (3):1187-98 Serum IgE clearance is facilitated by human FcεRI internalization.
Dutertre CA et al. PLoS One 2014; 9 (2):e89983 Deciphering the stromal and hematopoietic cell network of the adventitia from non-aneurysmal and aneurysmal human aorta.
Krummey SM et al. Am J Transplant 2014; 14 (3):607-14 High CTLA-4 expression on Th17 cells results in increased sensitivity to CTLA-4 coinhibition and resistance to belatacept.
Klco JM et al. Cancer Cell 2014; 25 (3):379-92 Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.
Baravalle G et al. J Immunol 2014; 192 (7):3280-8 Antigen-conjugated human IgE induces antigen-specific T cell tolerance in a humanized mouse model.
Walkowski S et al. PLoS One 2014; 9 (3):e90132 Osteopathic manipulative therapy induces early plasma cytokine release and mobilization of a population of blood dendritic cells.
Glauzy S et al. PLoS One 2014; 9 (3):e91492 CXCR4-related increase of circulating human lymphoid progenitors after allogeneic hematopoietic stem cell transplantation.
Imam S et al. Endocr Relat Cancer 2014; 21 (3):505-16 Lymphocytic profiling in thyroid cancer provides clues for failure of tumor immunity.
Nguyen KD et al. Mol Immunol 2014; 59 (2):172-9 Serum amyloid A induces mitogenic signals in regulatory T cells via monocyte activation.
Rongvaux A et al. Nat Biotechnol 2014; 32 (4):364-72 Development and function of human innate immune cells in a humanized mouse model.
Pa?no T et al. PLoS One 2014; 9 (3):e92378 Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines.
Sennikov SV et al. Mediators Inflamm 2014; 2014:745909 Polymorphisms in the tumor necrosis factor receptor genes affect the expression levels of membrane-bound type I and type II receptors.
Abramowski P et al. PLoS One 2014; 9 (3):e91970 The orally available, synthetic ether lipid edelfosine inhibits T cell proliferation and induces a type I interferon response.
Mukthavaram R et al. J Control Release 2014; 183:146-53 Targeting and depletion of circulating leukocytes and cancer cells by lipophilic antibody-modified erythrocytes.
Cartellieri M et al. PLoS One 2014; 9 (4):e93745 A novel ex vivo isolation and expansion procedure for chimeric antigen receptor engrafted human T cells.
Todd SK et al. Rheumatology (Oxford) 2014; 53 (9):1693-703 Regulatory B cells are numerically but not functionally deficient in anti-neutrophil cytoplasm antibody-associated vasculitis.