United States (US)

CD44v6 antibody [CD44v6/1246]

Anti-CD44v6 antibody [CD44v6/1246] used in IHC (Paraffin sections) (IHC-P). GTX34522
Anti-CD44v6 antibody [CD44v6/1246] used in IHC (Paraffin sections) (IHC-P). GTX34522

Cat No. GTX34522

Host Mouse
Clonality Monoclonal
Clone Name CD44v6/1246
Isotype IgG2a
Application ICC/IF, IHC-P
Reactivity Human

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 0.5-1ug/ml
IHC-P 0.5-1ug/ml for 30 minutes at RT

Note :

Boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

82 kDa. ( Note )


This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.




Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.


Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species



Recombinant fragment corresponding to the v6 domain of human CD44 (exact sequence is proprietary)


Ab purified from Bioreactor Concentrate by Protein A/G




For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.


Cd44 Molecule (Indian Blood Group),Cdw44,Cspg8,Ecmr-Iii,Hcell,Hutch-I,In,Lhr,Mc56,Mdu2,Mdu3,Mic4,Pgp1,Cd44


The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]


Research Area

Anti-CD44v6 antibody [CD44v6/1246] used in IHC (Paraffin sections) (IHC-P). GTX34522

GTX34522 IHC-P Image

Formalin-paraffin human Tongue Carcinoma stained with CD44v6 Monoclonal Antibody (CD44v6/1246)

Anti-CD44v6 antibody [CD44v6/1246] used in IHC (Paraffin sections) (IHC-P). GTX34522

GTX34522 IHC-P Image

Formalin-paraffin human Cervical Carcinoma stained with CD44v6 Monoclonal Antibody (CD44v6/1246)

Package List Price ($)
$ 329