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CD81 antibody [1.3.3.22]

Anti-CD81 antibody [1.3.3.22] used in IHC (Paraffin sections) (IHC-P). GTX34568
Anti-CD81 antibody [1.3.3.22] used in IHC (Paraffin sections) (IHC-P). GTX34568

Cat. No. GTX34568

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1.3.3.22

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, FACS

Reactivity

 Human, Mouse, Rat
Package
100 μg ($529)
See all CD81 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml for 2 hours at RT
ICC/IF 1-2μg/ml
IHC-P 2-4μg/ml for 30 minutes at RT
FACS 1-2μg/10⁶ cells

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human CD81 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD81 , CD81 molecule , CVID6 , S5.7 , TAPA1 , TSPAN28

Cellular Localization

Membrane

Background

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Database

Research Area

DATA IMAGES

Anti-CD81 antibody [1.3.3.22] used in IHC (Paraffin sections) (IHC-P). GTX34568

GTX34568 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX34568 CD81 antibody [1.3.3.22].

Anti-CD81 antibody [1.3.3.22] used in IHC (Paraffin sections) (IHC-P). GTX34568

GTX34568 IHC-P Image

IHC-P analysis of human lymph node tissue using GTX34568 CD81 antibody [1.3.3.22].

REFERENCE

Application Reference

Sara B York et al. mSphere 2021; : e0019221 Zika Virus Hijacks Extracellular Vesicle Tetraspanin Pathways for Cell-to-Cell Transmission.
Application : WB

Clone Reference

J Immunother Cancer 2023; 11 (7):e004043corr1 Exosomal CD73 from serum of patients with melanoma suppresses lymphocyte functions and is associated with therapy resistance to anti-PD-1 agents
Application : WB
Reactivity : Human
Sedik et al. BMC Musculoskeletal Disorders 2023; 24:205 Biological efect of bone marrow mesenchymal stem cell- derived extracellular vesicles on the structure of alveolar bone in rats with glucocorticoid-induced osteoporosis
Application : FACS
Reactivity : Rat
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529