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CEA antibody [CEA31]

Cat. No. GTX01652

Reference 5

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 CEA31

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all CEA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

Positive Control

Colon carcinoma

Product Note

Clone CEA31 has a high affinity for CEA and shows no detectable reactivity to nonspecific cross-reacting antigen (NCA), biliary glycoprotein (BGP) and human polymorphonuclear leucocytes.

PROPERTIES

Form

Liquid

Buffer

Tris-HCl buffer, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human colon carcinoma extract

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

carcinoembryonic antigen related cell adhesion molecule 3 , CD66D , CEA , CGM1 , W264 , W282

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]

Database

Research Area

REFERENCE

Clone Reference

2020; High Grade Transformation in Mucoepidermoid Carcinoma of the Minor Salivary Gland with Polyploidy of the Rearranged MAML2 Gene
Application : IHC-P
Reactivity : Human
2019; Coping with formalin banning in pathology: under vacuum long-term tissue storage with no added formalin
Application : IHC-P
Reactivity : Human
2019; Glypican-3 and Hep Par-1 are Useful Biomarkers in the Cytologic Assessment of Ascites
Application : IHC-P
Reactivity : Human
2018; Co-localisation of Glandular and Squamous Cell Markers in Non-small Cell Lung Cancer
Application : IHC-P
Reactivity : Human
2017; Clinical and pathological characteristic of metastatic malignant mesothelioma initially diagnosed by lymph node biopsy
Application : IHC-P
Reactivity : Human
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Package List Price ($)
$ 399