The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 ºC. We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous
Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
C-X-C Motif Chemokine Ligand 2,Cinc-2A,Gro2,Grob,Mgsa-B,Mip-2A,Mip2,Mip2A,Scyb2,Cxcl2
MIP2 is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. MIP2 was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. MIP2 is an approximately 8 kD polypeptide of 73 amino acids. The precursor form of MIP2 consists of 100 amino acids. To generate the mature MIP2, the precursor cleaves its amino-terminal 27 amino acids. MIP2 shows 60% amino acid homology to human GRO beta and GRO gamma.