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CYP3A4 antibody

Anti-CYP3A4 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53947
Anti-CYP3A4 antibody used in Western Blot (WB). GTX53947
Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947
Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947
Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947
Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947

Cat No. GTX53947

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
ICC/IF 1:20-1:100
IHC-P 1:20-1:50
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cytochrome P450 family 3 subfamily A member 4 , CP33 , CP34 , CYP3A , CYP3A3 , CYPIIIA3 , CYPIIIA4 , HLP , NF-25 , P450C3 , P450PCN1

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]

Database

Research Area

DATA IMAGES

Anti-CYP3A4 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53947

GTX53947 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX53947 CYP3A4 antibody.
Blue : DAPI
Dilution : 1:100

Anti-CYP3A4 antibody used in Western Blot (WB). GTX53947

GTX53947 WB Image

WB analysis of various sample lysates using GTX53947 CYP3A4 antibody.
Loading : 25ug per lane
Dilution : 1:1000

Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947

GTX53947 IHC-P Image

IHC-P analysis of human liver tissue using GTX53947 CYP3A4 antibody.
Dilution : 1:100

Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947

GTX53947 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX53947 CYP3A4 antibody.
Blue : DAPI
Dilution : 1:100

Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947

GTX53947 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX53947 CYP3A4 antibody.
Dilution : 1:100

Anti-CYP3A4 antibody used in IHC (Paraffin sections) (IHC-P). GTX53947

GTX53947 IHC-P Image

IHC-P analysis of rat ovary tissue using GTX53947 CYP3A4 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for CYP3A4 antibody (GTX53947). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for CYP3A4 antibody (GTX53947). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf