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Choline Acetyltransferase antibody

Anti-Choline Acetyltransferase antibody used in IHC (Paraffin sections) (IHC-P). GTX85450
Anti-Choline Acetyltransferase antibody used in IHC (Paraffin sections) (IHC-P). GTX85450
Anti-Choline Acetyltransferase antibody used in IHC (Paraffin sections) (IHC-P). GTX85450

Cat No. GTX85450

Host

Chicken

Clonality

Polyclonal

Isotype

IgY

Application

ICC/IF, IHC-P, IHC

Reactivity

Human, Mouse, Rat
Package
50 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
IHC 1:1000-1:2000
Not tested in other applications.

Calculated MW

83 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS + sodium azide (0.02%, w/v)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

100 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. The peptide corresponded to a region of the Choline Acetyltransferase gene product shared between the human (P28329, NCBI) and mouse (Q03059, NCBI) sequences.

Purification

PBS, sodium azide (0.02%, w/v)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

choline O-acetyltransferase , CHOACTASE , CMS1A , CMS1A2 , CMS6

Background

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Choline Acetyltransferase antibody used in IHC (Paraffin sections) (IHC-P). GTX85450

GTX85450 IHC-P Image

IHC-P analysis of 4% PFA-fixed mouse caudate nucleus section using GTX85450 Choline Acetyltransferase antibody. The green staining is low-level GFP immunoreactivity in this transgenic animal.
Red : Primary antibody

Anti-Choline Acetyltransferase antibody used in IHC (Paraffin sections) (IHC-P). GTX85450

GTX85450 IHC-P Image

IHC-P analysis of 4% PFA-fixed mouse caudate nucleus section using GTX85450 Choline Acetyltransferase antibody. The green staining is low-level GFP immunoreactivity in this transgenic animal.
Red : Primary antibody

Anti-Choline Acetyltransferase antibody used in IHC (Paraffin sections) (IHC-P). GTX85450

GTX85450 IHC-P Image

IHC-P analysis of 4% PFA-fixed mouse caudate nucleus section using GTX85450 Choline Acetyltransferase antibody. The green staining is low-level GFP immunoreactivity in this transgenic animal.
Red : Primary antibody

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf