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Cofilin 1 antibody

Anti-Cofilin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX02271
Anti-Cofilin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX02271
Anti-Cofilin 1 antibody used in Western Blot (WB). GTX02271

Cat No. GTX02271

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
IHC-P 1:10000-1:20000
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2 μm filtered PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human CFL1 / cofilin protein

Purification

Purified by Protein A and Antigen Affinity

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

cofilin 1 , CFL , HEL-S-15 , cofilin

Cellular Localization

Cytoplasm, cytoskeleton

Background

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Database

Research Area

DATA IMAGES

Anti-Cofilin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX02271

GTX02271 IHC-P Image

IHC-P analysis of human breast carcinoma tissue section using GTX02271 Cofilin 1 antibody.
Dilution : 1:20000

Anti-Cofilin 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX02271

GTX02271 IHC-P Image

IHC-P analysis of human hepatoma tissue section using GTX02271 Cofilin 1 antibody.
Dilution : 1:20000

Anti-Cofilin 1 antibody used in Western Blot (WB). GTX02271

GTX02271 WB Image

WB analysis of various samples using GTX02271 Cofilin 1 antibody.
Lane A : Jurkat whole cell lysate
Lane B : A431 whole cell lysate
Lane C : MCF-7 whole cell lysate
Dilution : 1:500
Loading : 30 μg

REFERENCE

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REVIEW

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