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DAND5 antibody [25D4]

Cat No. GTX53086

Host Mouse
Clonality Monoclonal
Clone Name 25D4
Isotype IgG1
Application ELISA
Reactivity Human
Package
100 μg ($329)
APPLICATION

Application Note

ELISA(1:1000-2000)

Calculated MW

20 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes human DAND5 by ELISA.
PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant Human DAND5.

Purification

The IgG fraction of culture supernatant was purified by Protein G affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dan Domain Bmp Antagonist Family Member 5 , Cer2 , Cerl2 , Cktsf1B3 , Coco , Crl2 , Dante , Grem3 , Sp1 , Dand5

Background

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]

Database

REFERENCE
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REVIEW
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SDS
PBS.pdf
Package List Price ($)
$ 329